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Öğe Fasciola hepatica egg-induced granuloma in a bovine liver: A case report(2007) Kaya, Galip; Atesoglu, Emine Ozlem; Akca, AtilaThe trematode parasite Fasciola hepatica infects a wide variety of mammals, causing considerable economical losses in domestic animals. It is also an important zoonosis. The major pathology of fasciolosis is caused by immature flukes migrating in the liver parenchyma and later by adult flukes in the bile ducts. Egg related immunopathology, commonly observed in the closely related parasite Schistosoma sp., is not normally expected in fasciolosis because the parasite matures and produces eggs in the bile ducts. However, the paper reports a case of Fasciola hepatica-egg induced granuloma in a bovine liver parenchyma and discusses its significance in the pathogenesis of fasciolosis.Öğe Hatay yöresinde kene kaynaklı Lyme Borelyozu Seroprevalansı(2012) Özeren, Gül Sultan; Kaya, Galip; Önlen, YusufAmaç: Kene tutunması vakalarına son yıllarda artan sıklıkla rastlanan Hatay yöresinde kene kaynaklı Lyme borelyozu varlığının saptanması amaçlanmıştır.Yöntemler: Kenelerin aktif olduğu Nisan-Ekim ayları arasında Hatay il merkezinde ve ilçelerinde yaşayan ve kene tutunması öyküsü olan 65 bireyden, kene temasının üzerinden en az 6 hafta geçmiş olması göz önünde bulundurularak alınan kan örneklerinde ELISA yöntemiyle Borrelia burgdorferi IgG ve IgM antikorları araştırılmıştır. Daha önce keneyle hiç karşılaşmamış olduğunu belirten 105 birey, kontrol grubunu oluşturmuştur. Bulgular: IgM antikorları, kene tutunması öyküsü olan 65 bireyin 45 (%69.2)'inde pozitif ve 5 (%7.7)'inde negatifken, kene tutunması öyküsü olmayan 105 bireyin 1 (%0.95)'inde pozitif bulunmuştur. Ayrıca, kene tutunması olanlardan 15 (%23.1)'inin, olmayanlarınsa 70 (%66.7)'inin gri zonda oldukları saptanmıştır. Sonuçlar: Hatay yöresinde farklı sağlık birimlerine başvuran risk altındaki her birey için yapılacak tanısal testler aşamasında, Lyme hastalığının da düşünülmesi gerekmektedir. Kene tutunması öyküsü olan kişilerin akut/kronik Lyme hastalığı olgularına dönüşüp dönüşmedikleri izlenmeli ve Lyme hastalığının prevalans ve insidansının gerek ülkemizde gerekse bölgemizde kesin olarak belirlenmesini sağlayacak çalışmalar yapılmalıdır. Klimik Dergisi 2012; 25(2): 58-62.Öğe Occurrence of Trypanosoma sp in wild African sharptooth catfish (Clarias gariepinus Burchell, 1822) in the River Asi (north-eastern Mediterranean), Turkey(Tubitak Scientific & Technological Research Council Turkey, 2010) Konas, Egemen; Genc, Ercuement; Kaya, Galip; Erol, CavitFifteen African sharptooth catfish (Clarias gariepinus Burchell, 1822) were collected from the River Asi (River Orontes) in Antakya (Hatay, Turkey) in November 2007, and fish blood samples were examined for the presence of blood parasites. The existence of infection with Trypanosoma (hemoparasite) was identified in 13 out of the 15 fish specimens. Currently there are no records of the presence of any species of Trypanosoma infecting Clarias gariepinus in Anatolia. Thus this study is the first report of Trypanosoma sp. infections in Clarias gariepinus in Turkey.Öğe Occurrence of Trypanosoma sp. in wild African sharptooth catfish (Clarias gariepinus Burchell, 1822) in the River Asi (north-eastern Mediterranean), Turkey(2010) Konaş, Egemen; Genç, Ercüment; Kaya, Galip; Erol, CavitFifteen African sharptooth catfish (Clarias gariepinus Burchell, 1822) were collected from the River Asi (River Orontes) in Antakya (Hatay, Turkey) in November 2007, and fish blood samples were examined for the presence of blood parasites. The existence of infection with Trypanosoma (hemoparasite) was identified in 13 out of the 15 fish specimens. Currently there are no records of the presence of any species of Trypanosoma infecting Clarias gariepinus in Anatolia. Thus this study is the first report of Trypanosoma sp. infections in Clarias gariepinus in Turkey.Öğe Seroprevalence of Tick-Borne Lyme Borreliosis in Hatay(Aves, 2012) Ozeren, Gul Sultan; Kaya, Galip; Onlen, YusufObjective: The objective of this study is to determine the presence of Lyme borreliosis transmitted by ticks in Hatay, where cases of tick bites recently increased. Methods: Blood samples collected from 65 persons at least 6 weeks after their tick bite incident who were living in Hatay (Antakya) city and surrounding districts were tested to determine the presence of Borrelia burgdorferi IgG and IgM antibodies by ELISA between April and October, the active tick period. As a control group, 105 persons without a tick bite history were tested as well. Results: Of 65 persons with a history of tick bite, 45 (69.2%) were IgM-positive and 5 (7.7%) were IgM-negative, while only 1 (0.95%) individual was IgM-positive among people without a tick bite history. In addition, 15 (23.1%) people with a history of tick bite, and 70 (66.7%) control individuals were identified in the grey zone. Conclusions: Lyme disease should be taken into consideration for patients who are at risk in Hatay and its surroundings when they apply to health facilities. Each tick bite case should be followed up in order to determine if they develop acute or chronic Lyme disease. Detailed investigations should be performed to determine the prevalence and incidence of Lyme disease in the whole country, including our region.Öğe Serum sialic acids, total antioxidant capacity, and adenosine deaminase activity in cattle with theileriosis and anaplasmosis(Natl Veterinary Research Inst, 2008) Guzel, Murat; Askar, Tunay Kontas; Kaya, Galip; Atakisi, Emine; Avci, Gulcan ErbilIn the present study, we aimed to provide information on the serum content of sialic acids (TSA, LBSA, and PBSA), total antioxidant capacity (TAC), and adenosine deaminase (ADA) activity in cattle affected with naturally acquired theileriosis and anaplasmosis. A total of 55 Holstein cattle, comprising of 15 clinically healthy control animals, 20 cattle with theileriosis, and 20 with anaplasmosis, were used. Diagnosis was based on clinical signs, Giemsa stained blood or lymph node aspirate, and PCR assay. For the PCR assay, Tams I primers were used. The obtained results suggested that the concentration of sialic acids and ADA activity were significantly higher; and TAC were significantly lower in the theileriosis and anaplasmosis groups in contrast to the control group. In conclusion, the increased level of sialic acids and ADA in theileriosis and anaplasmosis may be attributable to the stimulation of the host immune response. In contrast, the reduced level of TAC may reflect a decrease in the antioxidant capacity.