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    Öğe
    Fragmented QRS complexes are associated with postoperative atrial fibrillation development after coronary artery bypass grafting surgery
    (Lippincott Williams & Wilkins, 2021) Keskin, Hasan Attila; Kurtul, Alparslan
    Objective Postoperative atrial fibrillation (PoAF) is one of the most frequent complications and a major risk factor of morbidity and mortality after coronary artery bypass grafting (CABG). Fragmented QRS complex (fQRS) on a 12-lead surface ECG is recently gained increasing attention as a simplified noninvasive ECG marker with diagnostic and prognostic value in various cardiac conditions. The aim of the present study was to evaluate the association between development of PoAF and presence of fQRS on admission ECG in patients undergoing CABG surgery. Methods A total of 242 patients who underwent CABG between February 2016 and June 2018 were included in this study. The patients were divided into two groups as developing and nondeveloping PoAF groups in the postoperative period. fQRS was defined as the presence of various RSR ' patterns including an additional R wave, notching of the R or S waves, or the presence of more than one fragmentation in two contiguous leads. Results In-hospital mortality was higher in PoAF (+) group compared to PoAF (-) group (20.5 vs. 6.4%, P = 0.004). PoAF rate was higher in fQRS (+) group than fQRS (-) group (25.3 vs. 9.8%, P = 0.001). In multivariate analysis, the presence of fQRS complexes on admission ECG [odds ratio (OR) 2.801, 95% confidence interval (CI) 1.262-6.211, P = 0.011) and hemoglobin (OR 0.794; 95% CI, 0.641-0.985; P = 0.036) were identified as independent predictors of PoAF after CABG surgery. Conclusion The presence of fQRS on admission ECG was found to be an independent predictor of PoAF in patients undergoing isolated CABG.
  • Küçük Resim
    Öğe
    Prognostic nutritional index predicts in-hospital mortality in patients with acute Stanford type A aortic dissection
    (Sage Publications Ltd, 2021) Keskin, Hasan Attila; Kurtul, Alparslan; Esenboga, Kerim; Cicek, Mustafa Cuneyt; Katircioglu, Salih Fehmi
    Background: Acute Stanford type A aortic dissection (ATAAD) is a life-threatening medical emergency. The aim of this study was to investigate the clinical significance of the prognostic nutritional index (PNI) as a novel inflammatory marker for ATAAD patients undergoing surgical repair. Methods: We retrospectively examined the medical records of 151 ATAAD patients who treated surgically. Patients were divided into two groups (survival and death) and these groups were compared with respect to clinical and laboratory parameters. The PNI was calculated as 10 x serum albumin (g/dL) + 0.005 x total lymphocyte count (per mm(3)). Logistic regression analyses were performed to identify the risk factors of in-hospital mortality. Results: The mean age of the study cohort was 61 +/- 12 years, 99 (65.6%) were males, and 35 (23.2%) patients died during the hospital stay. The PNI levels were significantly lower in death group compared with survival group (32.80 +/- 4.90 vs. 37.94 +/- 5.42, p < 0.001). Multivariate analysis showed that the PNI (OR: 0.795, p = 0.005), age (odds ratio [OR]: 1.085, p = 0.034), operating time (OR: 1.660, p = 0.042), and D-dimer (OR: 1.002, p = 0.001) independently predicted in-hospital mortality. The calculated cutoff value of the PNI was 33.01. Conclusion: Lower PNI values are independently associated with in-hospital mortality in ATAAD. The PNI may be a useful tool for predicting the early mortality of ATAAD patients after surgical repair.