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Öğe Beyond expectations: disease duration and psychological burden in psoriatic arthritis(Springer Heidelberg, 2023) Kilic, Gamze; Kilic, Erkan; Tekeoglu, Ibrahim; Sargin, Betul; Cengiz, Gizem; Balta, Nihan Cuzdan; Alkan, HakanThis study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classification criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (< 5 years), middle stage (& GE; 5, < 10 years), and late stage (& GE; 10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR = 1.52), PsAQoL (OR = 1.13), HAQ (OR = 1.99), FiRST score (OR = 1.14), unemployment/retired (OR = 1.48) and PASI head score (OR = 1.41) were factors that influenced the risk of depression, whereas the current or past enthesitis (OR = 1.45), PsAQoL (OR = 1.19), and FiRST score (OR = 1.26) were factors that influenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.Öğe Diagnostic delay in psoriatic arthritis: insights from a nationwide multicenter study(Springer Heidelberg, 2024) Kilic, Gamze; Kilic, Erkan; Tekeoglu, Ibrahim; Sargin, Betul; Cengiz, Gizem; Balta, Nihan Cuzdan; Alkan, HakanThis study aimed to investigate the duration of diagnostic delay in patients with psoriatic arthritis (PsA) and identify potential contributing factors using a comprehensive, population-based approach. Data were obtained from the Turkish League Against Rheumatism (TLAR)-Network, involving patients who met the CASPAR criteria. Diagnostic delay was defined as time interval from symptom onset to PsA diagnosis, categorized as <= 2 years and > 2 years. Temporal trends were assessed by grouping patients based on the year of diagnosis. Various factors including demographics, clinical characteristics, disease activity, quality of life, physical function, disability, fatigue, and well-being were examined. Logistic regression models were used to identify factors associated with diagnostic delay. Among 1,134 PsA patients, mean diagnostic delay was 35.1 months (median: 12). Approximately 39.15% were diagnosed within 3 months, and 67.02% were diagnosed within 24 months. Patients experiencing longer delays had higher scores in Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), patient's global assessment (PtGA) and physician's global assessment (PhGA). Diagnostic delay has decreased over time, with median delay falling from 60 to 24 months throughout pre-2010 and 2015-2019 terms. Several factors were identified as significant contributors to delayed diagnosis, including lower levels of education (OR = 2.63), arthritis symptoms preceding skin manifestations (OR = 1.72), low back pain at first visit (OR = 1.60), symptom onset age (OR = 0.96), and psoriasis subtype (OR = 0.25). Timely diagnosis of PsA is crucial for effective management and improved outcomes. Despite recent improvements, about one-third of PsA patients still experience delays exceeding 2 years. By identifying influential factors such as education level, arthritis symptoms preceding skin manifestations, initial visit symptoms, age of symptom onset, and psoriasis subtype, healthcare practitioners may create specific techniques to help in early detection and intervention.Öğe EFFECTIVENESS OF VARIOUS ATTRACTANTS FOR MEDITERRANEAN FRUIT FLY, CERATITIS CAPITATA (WIEDEMANN) (DIPTERA: TEPHRITIDAE) ON POMEGRANATE FRUITS IN TURKEY(Parlar Scientific Publications (P S P), 2018) Demirel, Nihat; Yildirim, Ahmet Emin; Kilic, GamzeThe Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), is a serious pest on pomegranate fruits in Turkey. The objective of this study was to determine effectiveness of various attractants to Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) on pomegranate fruits in Hatay province of Turkey. The Decis traps baited with various attractants impregnated in paper handkerchief dispensers were used. After two years of the study, effectiveness of various attractants to C. capitata varied in each of the pomegranate variety and sampling year. In the first year, the highest mean of catches on Ilicaz' pomegranate were observed on the combination of ammonium acetate + ammonium bicarbonate attractant traps. In addition, the highest mean of catches on 'Katirbasi' pomegranate were observed on the combination of ammonium acetate + ammonium bicarbonate + putrescine attractant traps. However, the lowest mean of catches on 'Hicaz' and 'Katirbase pomegranate were observed on the combination of ammonium bicarbonate + trimethylamine + putrescine attractant traps in both studies. In the second year, the highest mean of catches on 'Hicaz' I, II pomegranate were observed on the combination of ammonium acetate + ammonium carbonate attractant traps in both studies. On the other hand, the lowest mean of catches on 'Hicaz' I, II pomegranate were observed on the combination of ammonium acetate + trimethylamine + putrescine and a single ammonium acetate attractant traps. The highest mean of catches on Katirbasi pomegranate were observed on the combination of ammonium acetate + trimethylamine + cadaverine attractant traps, whereas the lowest mean of catches were observed on the combination of ammonium acetate + trimethylamine + putrescine and a single ammonium acetate attractant traps. The highest percentages of damage ratios were observed on 'Hicaz' (18%) in 2015 and (14%) in 2016.Öğe A POPULATION FLUCTUATION AND DAMAGE RATES OF CERATITIS CAPITATA (DIPTERA: TEPHRITIDAE) ON PERSIMMON FRUITS IN TURKEY(Parlar Scientific Publications (P S P), 2018) Kilic, Gamze; Demirel, NihatThe Mediterranean fruit fly (Medfly), Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), is a serious pest on persimmon fruits in Turkey. The study was conducted in 2013-2014 to evaluate population fluctuation and damage rates of C. capitata on persimmon fruits in Hatay province of Turkey. The eostrap (R) invaginada traps baited with % 95 trimedlure impregnated in a polymeric plug-type dispenser were used. After two years of the study, the mean of catches, percentages of male and female and damage ratio of C. capitata varied in the sampling period and orchard. In 2013, the largest mean of catches per trap were recorded on 4 August in Belen and 25 August in Harbiye districts. The percentages of male per trap with 78.69 in Belen and 91.35 in Harbiye districts were higher than females with 21.31 in Belen and 8.65 in Harbiye districts. In 2014, the largest mean of catches per trap were recorded on 10 August in Belen and 17 August in Harbiye districts. The percentages of male per trap with 84.62 in Belen and 67.47 in Harbiye districts were higher than females with 15.38 in Belen and 32.53 in Harbiye districts. The percentages of damage ratio of C. capitata varied in each of the sampled orchard in both years. In 2013, the highest damage ratio of this pest was observed at the Belen IX orchard with 10.08 percent. In 2014, the highest damage ratio of C. capitata was observed at the Harbiye III orchard with 7.01 percent. In conclusion, the largest mean catches and percentages of male and female per trap were significantly high in August in both years and the percentages of damage ratio of this pest increased ripening and harvesting time of persimmon fruits in Hatay province of Turkey.
