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Öğe Addition of avilamycin, mannanoligosaccharide and organic acids mixture to corn-soybean meal based broiler diets(2005) Sarica, S.; Erdogan, S.; Koc, A.; Erdogan, Z.This study was conducted to compare the effects of mannanoligosaccharide (MOS) and organic acids mixture (OAM) alone or in combination as alternative feed additives to an antibiotic growth promoter (avilamycin) on the growth performance, some plasma parameters and histological parameters of the small intestine of male broiler chickens. The chicks were randomly assigned to 5 dietary treatments: control, avilamycin, MOS, OAM and MOS plus OAM supplemented diets. The dietary treatments did not significantly influence the body weight gain, feed intake and feed efficiency from 7 to 42 day. No significant effect on some plasma parameters was observed by the dietary treatments. Crypt depths in the duodenum were not influenced by the dietary treatments. However, the depths of the crypts in the jejenum of the treatment groups decreased significantly (P<0.05) compared with control. The depths of the crypts in the ileum were significantly reduced by supplementation of dietary avilamycin, MOS and MOS plus OAM in comparison to the control and diet supplemented with OAM only (P<0.05). It is possible that the level of mannanoligosaccharide and organic acids mixture used in the study was not sufficient to elicit a significant response.Öğe BENEFICIAL EFFECT OF ERDOSTEINE ON METHOTREXATE-INDUCED TESTICULAR TOXICITY IN MICE(Elsevier Science Bv, 2010) Oktar, S.; Gokce, A.; Aydin, M.; Davarci, M.; Meydan, S.; Ozturk, O. H.; Koc, A.[Abstract Not Available]Öğe Inhibitory effects of acetylsalicylic acid on exocrine pancreatic carcinogenesis(Taylor & Francis Ltd, 2013) Yildiz, H.; Oztas, H.; Yildiz, D.; Koc, A.; Kalipci, E.We investigated short (6 months) and long (12 months) term inhibitory effects of low (200 ppm) and high (400 ppm) dosages of acetylsalicylic acid (aspirin) on exocrine pancreatic carcinogenesis. It is known that exocrine pancreatic carcinogenesis can be detected by the presence of atypical acinar cell foci (AACF) in pancreas. We investigated possible inhibitory effects of acetylsalicylic acid in an azaserine-treated rat model. AACF were produced in rats by injection with azaserine according to previous studies. Our findings showed that the number, volume and diameter of pancreatic AACF were reduced after acetylsalicylic acid application. These observations suggest that acetylsalicylic acid may exert a protective effect against neoplastic development of pancreatic acinar cells in azaserine injected rats. Our findings corroborate reports in the literature concerning the effects of aspirin in reducing neoplastic development.Öğe PROTECTIVE EFFECT OF THYMOQUINONE IN EXPERIMENTAL TESTICULAR TORSION(Elsevier Science Bv, 2010) Gokce, A.; Oktar, S.; Koc, A.; Gonenci, R.; Yalcinkaya, F.; Yonden, Z.; Duru, M.[Abstract Not Available]Öğe The protective role of N-acetylcysteine on cyclosporine A-induced nephrotoxicity in rats(Blackwell Publishing, 2006) Oksuz, H.; Sogut, S.; Koc, A.; Uz, E.; Tamer, C.; Yilmaz, H.; Duru, M.[Abstract Not Available]