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Öğe THE COMPARISON OF VACUUM ASSISTED CLOSURE AND CONVENTIONAL COTTON GAUZE DRESSING IN THE TREATMENT OF DEFECTIVE LOWER EXTREMITY INJURIES(Carbone Editore, 2014) Ozden, Raif; Duman, Ibrahim Gokhan; Uruc, Vedat; Dogramaci, Yunus; Kalacı, Aydıner; Komurcu, ErkamWe performed a retrospective analysis to compare the efficacy of the vacuum assisted closure (VAC) therapy and conventional cotton gauze dressing of wounds. From July 2011 to August 2013, 40 patients were included in the study. All patients were reconstructed with split thickness skin graft after the granulation tissue was sufficient Two groups of 20 patients Were compared retrospectively. Data were collected for gender, age, time needed for sufficient granulation tissue for split thickness skin grafts, length of stay in hospital and. number of debridement for wound VAC application, and conventional cotton gauze dressing methods. Demographic data were the Same. for two groups. Time needed to have a good granulation tissue that was sufficient for split thickness skin graft, length of stay in hospital, and number of debridement were significantly less in VAC treatment group (P<0,05). No major complication occurred that was directly attributable to treament. VAC therapy appears to be a good adjunct for the treatment of musculoskeletal injuries and found to facilitate the rapid formation of healthy granulation tissue on wounds in the lower limb and shortens the length of stay in hospital.Öğe The comparison of vacuum assisted closure and conventional cotton gauze dressing in the treatment of defective lower extremity injuries(Acta Medica Mediterranea, 2014) Ozden, Raif; Duman, Ibrahim Gokhan; Uruc, Vedat; Dogramaci, Yunus; Kalacı, Aydıner; Komurcu, ErkamWe performed a retrospective analysis to compare the efficacy of the vacuum assisted closure (VAC) therapy and conventional cotton gauze dressing of wounds. From July 2011 to August 2013, 40 patients were included in the study. All patients were reconstructed with split thickness skin graft after the granulation tissue was sufficient. Two groups of 20 patients were compared retrospectively. Data were collected for gender, age, time needed for sufficient granulation tissue for split thickness skin grafts, length of stay in hospital and number of debridement for wound VAC application, and conventional cotton gauze dressing methods. Demographic data were the same for two groups. Time needed to have a good granulation tissue that was sufficient for split thickness skin graft, length of stay in hospital, and number of debridement were significantly less in VAC treatment group (P < 0.05). No major complication occurred that was directly attributable to treatment. VAC therapy appears to be a good adjunct for the treatment of musculoskeletal injuries and found to facilitate the rapid formation of healthy granulation tissue on wounds in the lower limb and shortens the length of stay in hospital.Öğe Effects of a Single Application of Adcon Gel on Peritendinous Adhesion: An Experimental Study in Rabbits(Journal Hard Tissue Biology, 2014) Ozden, Raif; Uruc, Vedat; Duman, Ibrahim Gokhan; Dogramaci, Yunus; Kalacı, Aydıner; Komurcu, Erkam; Ozsoy, Sule YurdagulPeritendinous adhesions are serious complications after surgical repair of tendons and can lead to poor functional outcome. In the present study, the tensile strength of repaired tendons was measured biomechanically in two groups using a rabbit Achilles tendon model, and the effects of Adcon gel on peritendinous adhesions and tendon healing were examined by means of histological and mechanical analyses. In the treatment group, the Achilles tendon was transected, followed by a primary repair using a modified Kessler technique, and Adcon gel was injected between the tendon and skin of the right leg. The same operation was done for the control group, and 1 mL of normal saline solution was applied locally in a similar fashion. The experimental protocols were approved by the local animal ethics committee. Microscopic evidence of the formation of adhesions and of inflammation was less in the treatment group than in the control group. There was no significant difference in the tensile load necessary to rupture the repaired tendons between the two groups. Adcon gel reduced the peritendinous adhesions histologically without impairing tendon healing, as determined with mechanical analyses. The use of Adcon gel may provide a simple means of preventing of postoperative peritendinous adhesions, thereby offering a beneficial effect on tendon repair.Öğe Effects of Local Administration of Boric Acid on Posterolateral Spinal Fusion with Autogenous Bone Grafting in a Rodent Model(Humana Press Inc, 2015) Komurcu, Erkam; Ozyalvacli, Gulzade; Kaymaz, Burak; Golge, Umut Hatay; Goksel, Ferdi; Cevizci, Sibel; Adam, GurhanSpinal fusion is among the most frequently applied spinal surgical procedures. The goal of the present study was to evaluate whether the local administration of boric acid (BA) improves spinal fusion in an experimental spinal fusion model in rats. Currently, there is no published data that evaluates the possible positive effects if the local administration of BA on posterolateral spinal fusion. Thirty-two rats were randomly divided into four independent groups: no material was added at the fusion area for group 1; an autogenous morselized corticocancellous bone graft was used for group 2; an autogenous morselized corticocancellous bone graft with boric acid (8.7 mg/kg) for group 3; and only boric acid was placed into the fusion area for group 4. The L4-L6 spinal segments were collected at week 6, and the assessments included radiography, manual palpation, and histomorphometry. A statistically significant difference was determined between the groups with regard to the mean histopathological scores (p=0.002), and a paired comparison was made with the Mann-Whitney U test to detect the group/groups from which the difference originated. It was determined that only the graft+BA practice increased the histopathological score significantly with regard to the control group (p=0.002). Whereas, there was no statistically significant difference between the groups in terms of the manual assessment of fusion and radiographic analysis (respectively p=0.328 and p=0.196). This preliminary study suggests that BA may clearly be useful as a therapeutic agent in spinal fusion. However, further research is required to show the most effective dosage of BA on spinal fusion, and should indicate whether BA effects spinal fusion in the human body.Öğe Safety and feasibility of lumbar spine for intralaminar screw fixation: a computed tomography-based morphometric study(Turkish Assoc Orthopaedics Traumatology, 2015) Komurcu, Erkam; Kaymaz, Burak; Adam, Gurhan; Golge, Umut Hatay; Goksel, Ferdi; Ozden, RaifObjective: The use of intralaminar screws (ILS) in spinal surgery has experienced a recent increase in popularity. The aim of this study is to define the morphological parameters of the lumbar laminas so that guidance may be defined for ILS placement. Methods: The study involved the evaluation of lumbar computed tomography (CT) images of patients. Two hundred thirty-five patients (127 male, 108 female) were included in the study. The mean patient age was 44.2 years (19-78 years). The measured parameters of the lamina were the transverse inner diameter, transverse outer diameter (lamina width), lamina length, subdural space (safe zone), and spinolaminar angle for each lumbar level (L1-L5). Results: The mean transverse outer diameter (L1-L5) ranged from 7.2-7.8 mm, and mean transverse inner diameter ranged from 2.5-3.0 mm. The lamina of L3 had the largest width and the lamina of L1 and L5 the smallest. The mean lamina length was 26.6 mm, ranging from 21.0-34.0 mm, and the mean spinolaminar angle was 124.7 degrees, ranging from 111-135 degrees. The L1 level had the shortest mean lamina length and L4 the lowest spinolaminar angle. Mean subdural space (safe zone), which was narrowest at the L5 level, was 2.4 mm, ranging from 1.3-3.6 mm. Conclusion: ILS of the appropriate size (3.5-4.5 mm) and length (20 and 25 mm) can be used safely in the lumbar spine. However, further biomechanical studies should be performed to measure strength of the fixation.Öğe Spontaneous atraumatic extensor pollicis longus rupture in healthy individuals due to steroid injection: Two case reports(Medi+World Int, 2014) Ozden, Raif; Uruc, Vedat; Duman, Ibrahim Gokhan; Dogramaci, Yunus; Kalacı, Aydıner; Komurcu, ErkamIntroduction: Local steroid injection is believed to be associated with risk of spontaneous tendon rupture. Spontaneous rupture of the extensor pollicis longus (EPL) tendon at the wrist is infrequent and essentially described after fracture of the distal radius. Rough bone ends, rheumatoid arthritis, lupus erythematosus, synovitis or tenosynovitis both contribute to this process. The aim of this study is to define rupture of the EPL tendon with review of the literature in two cases after receiving local steroid injections. Case presentation: The operative records for two patients undergoing EPL reconstruction by an author were criticized. All 2 patients had exposure to local steroids but this exposure was not into the ruptured tendon. It is administered about 2 cm away from the tendon. We identified 2 patients who presented with spontaneous EPL tendon rupture owing to steroid injection. These patients reported no risk factors or inciting event other than steroid injection. EPL were operatively repaired in two cases. At the 2-year follow-up, patients could completely extend the thumb. The cases were from the Eastern Mediterranean region of Turkey. Conclusion: In patients with unexpected loss of extension of the thumb interphalangeal joint, with a history of steroid injection, rupture of EPL tendon should be considered even if it was administered to remote location.