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  • Küçük Resim
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    Acrodysostosis associated with hypercalcemia
    (Hellenic Endocrine Soc, 2013) Kirnap, Mehmet; Calis, Mustafa; Gokce, Cumali; Kurtoglu, Selim; Ozturk, Mustafa; Kelestimur, Fahrettin
    An 18-year-old man was admitted to the clinic complaining of deterioration in the function of his hands and feet. The clinical examination revealed that his movements were clumsy and that he had disproportionally short limbs. In addition, he also had facial abnormalities of frontal bossing, hypertelorism, maxillary hypoplasia, broad low nasal bridge, short upturned nose with anteverted nostrils and triangular mouth. All extremities appeared short with stubby fingers and toes and with broad hands and wrinkling of the dorsal skin. Chromosomal analysis showed a normal (46, XY) karyotype. X-ray studies revealed broad, short metacarpals and phalanges with cone-shaped epiphyses and brachycdactyly and a diagnosis of peripheral dysostosis was confirmed by the characteristic radiographic appearance of the hands. Serum calcium and alkaline phosphatase levels were high, parathormone (PTH) was low, but 25 (OH) Vitamin D, albumin, and 24 hour urine calcium levels were in the normal range. Based on these findings, a diagnosis of acrodysostosis associated with hypercalcemia was made. To the best of our knowledge, this represents the first description of this syndrome.
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    Öğe
    Assessment of nutritional status: Triceps and subscapular skin-fold thickness in Turkish children and adolescent
    (Professional Medical Publications, 2011) Yuca, Sevil Ari; Cesur, Yasar; Yilmaz, Cahide; Mazicioglu, Mumtaz; Kurtoglu, Selim
    Objectives: To determine the mean and percentile values and constitute the percentile curves of the triceps and subscapular skin-fold thickness (SFT) for obtaining a measure to be used in evaluating nutritional status of children and adolescents for age and gender to determine the threat of adiposity in Turkish children. Methodology: This cross-sectional study was carried out between October 2006 and May 2007 with 6917 students selected among those with pre-defined socio-economic criteria and attending primary schools in Van city center. Based on these data, the subjects were distributed to age groups in 6-month intervals, beginning from the age of 7 up to the age of 17. Results: Analysis of mean values of the thickness of triceps and subscapular SFT according to age in boy subjects demonstrated that these values generally increased with age up to thirteen years of age where peak values were observed, and the thickness decreased between 14 and 15 years of age, increasing again thereafter. A comparison of our data with the data reported from other countries revealed lower than median values of triceps and subscapular SFT in our study for both girls and boys regardless of the age group. Conclusions: Subcutaneous fat accumulation is lower in Turkish children compared to those in other countries and no risk of obesity is imminent, at least in the region where this study was carried out.
  • Küçük Resim
    Öğe
    Iodine, copper, zinc, selenium and molybdenum levels in children aged between 6 and 12 years in the rural area with iodine deficiency and in the city center without iodine deficiency in Hatay
    (Aves, 2014) Celik, Tanju; Savas, Nazan; Kurtoglu, Selim; Sangun, Ozlem; Aydin, Zeki; Mustafa, Didin; Ozturk, Oktay Hasan
    Aim: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiencies which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). Material and Methods: This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanisma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. Results: Iodine deficiency was found with a severe (5%), moderate (18.4%) and mild degree (43%), respectively in the village of Tanisma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p < 0.001). A significant correlation was found between the levels of iodine, selenium, zinc and molybdenum (p < 0.05). A moderately positive correlation was found between iodine and selenium (p < 0.001). A moderately positive correlation was found between iodine and zinc levels (p < 0.001) and a weak correlation was found between iodine and molybdenum (p < 0.01). No significant correlation was found between iodine level and copper level (p > 0.05). Conclusions: Selenium and zinc deficiency may accompany iodine deficiency. Selenium and zinc deficiency should be considered in individuals who are found to have iodine deficiency especially in endemic goitre regions.