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Öğe Abdominal Aortic Aneurysm as a Long Time Cause of Low Back Pain and Vertebral Scalloping(Oxford Univ Press, 2016) Yildizgoren, Mustafa Turgut; Ogut, Halil; Kayali, Alperen; Turhanoglu, Ayse Dicle[Abstract Not Available]Öğe Diffuse Idiopathic Skeletal Hyperostosis with Cervical Vertebra Involvement: A Case Report(Galenos Yayincilik, 2021) Arslan, Mehmet; Ogut, Halil; Guler, Hayal; Turhanoglu, Ayse DicleDiffuse idiopathic skeletal hyperostosis is a non-inflammatory disease characterized by ossification and calcification in soft tissues, such as enthesis and joint capsules. The thoracic vertebra is often affected; however, cervical vertebra involvement can also be seen. Diagnosis is made by observing ossifications in the anterior surface of the four vertebrae and excluding spinal degenerative and inflammatory diseases. Pain and movement limitation is frequently observed in cervical vertebra involvement, but symptoms, such as dysphagia, hoarseness, and snoring, may also occur. This study aimed to present a 69-year-old male patient with pain in the neck and back, movement limitations, and swallowing difficulties, mostly with solid foods. The cervical imaging of the patient revealed anterior ossifications that compress the esophagus and posterior ossifications without myelomalacia. Surgery was recommended to the patient for his progressive dysphagia but was refused. Partial improvement was achieved in the patient's complaints with exercise and swallowing training in pain, movement limitation, and swallowing difficulties.Öğe The effect of oral baclofen and botulinum toxin treatments in hemiplegic spasticity on the nociceptive flexor reflex: A randomized clinical trial(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2022) Gunturk, Erturk; Ogut, Halil; Guler, Hayal; Turhanoglu, Ayse DicleObjectives: This study aimed to analyze the effect of oral baclofen treatment and botulinum toxin type A (BT-A) injection treatment in hemiplegic patients with spasticity on the electromyographic nociceptive flexor reflex (NFR) threshold. Patients and methods: A total of 29 spastic hemiplegic patients (20 males, 9 females; mean age: 52.9 +/- 10.1; range, 27 to 64) with Modified Ashworth Scale (MAS) grades 2-4 were included in the prospective, randomized study between May 2018 and March 2019. The patients were divided into two groups: the BT-A group consisted of 15 patients that underwent a BT-A injection and the baclofen group consisted of 14 patients treated with baclofen. Modified Ashworth Scale, Visual Analog Scale (VAS), Barthel daily life activity index, and NFR threshold values were used in the evaluation of the patients before and after the treatment at the sixth week. The motor evaluation of the patients was performed using Brunnstrom motor staging. Results: In both groups, MAS and VAS values decreased significantly compared to pretreatment (p<0.05). There was a significant decrease in ankle MAS score (p<0.001) and a significant increase in Brunnstrom hand recovery stages in the BT-A group compared to pretreatment (p=0.020). While the NFR threshold statistically significantly increased in the baclofen group compared to pretreatment (p=0.007), there was no significant change in the BT-A group (p=0.669). Conclusion: These results suggest that BT-A injections do not cause a significant change in the NFR threshold in the treatment of spasticity.Öğe Effects of a rehabilitation program for Parkinson's patients on reaction and movement time: an electromyographic study(Cukurova Univ, Fac Medicine, 2022) Kizil, Nurhan; Ogut, Halil; Okuyucu, Esra; Guler, Hayal; Ozer, Cahit; Turhanoglu, Ayse DiclePurpose: The aim of the study was to investigate the effects of a rehabilitation program consisting of specific exercises for Parkinson's Disease (PD) patients on reaction time (RT), movement time (MT), quality of life and disease activity. Materials and Methods: A total of 26 idiopathic PD patients were included in the study. The exercises specific to Parkinson's were applied to the patients for 16 weeks. The evaluation of the patients were done before and after the treatment. The disease severity was measured with Unified Parkinson's Disease Rating Scale (UPDRS), quality of life was measured with Short Form-36 (SF-36). RT and MT measurements were done electromyographically. Results: There was no statistically significant difference in UPDRS total and sub-section values and SF-36 quality of life evaluation before and after the exercise program. While a significant decrease was observed in the RT values of the patients after the 16 week exercise program compared to prior to the program (Deltoid RT 370.46 +/- 25 to 219.58 +/- 17, biceps RT 370.42 +/- 27 to 216.49 +/- 14 and triceps RT 445.21 +/- 31 to 247.53 +/- 23, respectively). Conclusion: In PD, the rehabilitation program specific to the disease leads to a significant decrease in RT. Although the exercise has no statistically significant effect on disease activity, quality of life and MT values, it was seen that it still led to improvement.Öğe Optical coherence tomography changes in ankylosing spondylitis patients on long-term adalimumab treatment(Assoc Medica Brasileira, 2022) Yavuz, Nurce Cilesizoglu; Ozer, Murat Atabey; Sari, Ilker Fatih; Kulakli, Sevgi; Tatli, Samet; Ogut, HalilOBJECTIVE: Long-term ocular effects of tumor necrosis factor-alpha inhibitors remain to be elucidated. This study aimed to examine the long-term effects of adalimumab use on neural tissue of the anterior visual pathways using optical coherence tomography in patients with ankylosing spondylitis.METHODS: This was a single-center, open-label, cross-sectional study conducted at the Giresun University Faculty of Medicine, Physical Medicine and Rehabilitation Department, between November 2019 and August 2020. This study included 26 ankylosing spondylitis patients receiving adalimumab for at least 1 year and 21 healthy controls. All subjects underwent a full ophthalmological examination and optical coherence tomography examination with the following measurements: peripapillary retinal nerve fiber layer thickness, peripapillary retinal thickness, peripapillary choroidal thickness, ganglion cell complex thickness, and the optic head properties.RESULTS: Peripapillary retinal nerve fiber layer thickness and retinal thickness measurements were lower in the adalimumab group. In addition, ganglion cell complex thickness was significantly lower and the cup-to-disc ratio was significantly higher in the adalimumab group (p<0.05). However, the two groups did not differ in terms of peripapillary choroidal thickness and disc area (p>0.05).CONCLUSION: Although tumor necrosis factor-alpha inhibitors have some favorable effects on the ocular involvement of patients with ankylosing spondylitis, they may also have paradoxical detrimental effects as evidenced by structural changes observed by optical coherence tomography. Future studies with better design, probably including a large number of patients with a range of rheumatological diseases and tumor necrosis factor-alpha inhibitors, are warranted.
