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Öğe The Consistency Between Clinical and Electrophysiological Diagnoses(Turkish Neurological Soc, 2009) Okuyucu, Esra E.; Turhanoglu, Ayse D.; Duman, Taskin; Savas, Nazan; Mengulluoglu, Necdet; Melek, Ismet M.Objective: The aim of this study was to provide information concerning the impact of electrophysiological tests in the clinical management and diagnosis of patients, and to evaluate the consistency between referring clinical diagnoses and electrophysiological diagnoses. Patients and Methods: The study included 957 patients referred to the electroneuromyography (ENMG) laboratory from different clinics with different clinical diagnoses in 2008. Demographic data, referring clinical diagnoses, the clinics where the requests wanted, and diagnoses after ENMG testing were recorded and statistically evaluated. Results: In all, 957 patients [ 644 (67.3%) female and 313 (32.7%) male] were included in the study. Mean age of the patients was 45.40 +/- 14.54 years. ENMG requests were made by different specialists; 578 (60.4%) patients were referred by neurologists, 122 (12.8%) by orthopedics, 140 (14.6%) by neurosurgeons, and 117 (12.2%) by physical treatment and rehabilitation departments. According to the results of ENMG testing, 513 (53.6%) patients' referrals were related to their referral diagnosis, whereas 397 (41.5%) patients had normal ENMG test results, and 47 (4.9%) patients had a diagnosis that differed from the referring diagnosis. Among the relation between the referral diagnosis and electrophysiological diagnosis according to the clinics where the requests were made, there was no statistical difference (p= 0.794), but there were statistically significant differences between the support of different clinical diagnoses, such as carpal tunnel syndrome, polyneuropathy, radiculopathy-plexopathy, entrapment neuropathy, and myopathy based on ENMG test results (p< 0.001). Conclusion: ENMG is a frequently used neurological examination. As such, referrals for ENMG can be made to either support the referring diagnosis or to exclude other diagnoses. This may explain the inconsistency between clinical referring diagnoses and diagnoses following ENMG.Öğe Correlation of sleep disorder and Parkinson's disease severity in Turkish patients(Riyadh Armed Forces Hospital, 2009) Okuyucu, Esra E.; Duman, Taskin; Melek, Ismet M.; Seydaoglu, Gulsah[Abstract Not Available]Öğe EEG abnormalities during treatment with tadalafil, a phosphodiesterase type 5 inhibitor(Taylor & Francis Ltd, 2009) Okuyucu, Esra E.; Guven, Oguz; Duman, Taskin; Gorur, Sadik; Melek, Ismet M.; Akcin, Soner; Yilmazer, SerkanObjective: Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. Method: EEG recordings from 35 erectile dysfunction patients taking tadalafil (20 mg) were graded for severity of EEG abnormalities (at admission, 2 and 48 hours after tadalafil administration). Results: At admission, there were no EEG abnormalities. At second EEG, abnormalities occurred in 12 (34.3%) of the 35 patients. Eight (22.9%) patients had mild and four (11.4%) patients had moderate EEG abnormalities. At third EEG, one (2.9%) patient had mild and one (2.9%) patient had moderate EEG abnormalities. Conclusion: PDE-5 inhibitors may produce EEG abnormalities. Although the exact role of PDE in altering susceptibility to seizure remains unclear, epileptic seizures may occur during treatment with PDE inhibitors. [Neurol Res 2009; 31: 313-315]Öğe Evaluation of Respiratory Function in Patients with Epileptic Seizures(Kare Publ, 2021) Gokcek, Ozden; Huzmeli, Irem; Hallaceli, Hasan; Melek, Ismet; Okuyucu, Esra E.Objectives: Respiratory problems increase the number of epileptic seizures in individuals with epileptic seizures. This study aimed to determine the relationship between the number of seizures, sleep quality, and respiratory problems by evaluating the changes in respiratory parameters of epileptic patients. Methods: Thirty individuals aged 18-40 years with generalized epilepsy were included in the study. Demographic data, number of seizures per week, pulse and blood pressure measurements, age of seizures, and body mass index were recorded. Dyspnea with mMRC; pulmonary function test; level of physical activity (PA) with International physical activity assessment survey (IPAQ); mouth pressure measuring device with respiratory muscle strength; and sleep quality with Pittsburgh Sleep Quality Index (PSQI) were evaluated. Results: Thirty patients with epileptic seizures (mean age: 26.56 +/- 6.64 years) were included in the study. The mean; % maximal inspiratory pressure (MIP) 67.44, %Maximal expiratory pressure (MEP) 35.14, MIP 70.47, and MEP 62.24 cmH(2)O were found.The forced expiratory volumes/ forced vital capacity (FEV1/FVC) (41.01%) and FEV1 (62.50%; 2.56 L) was found lower than the standards. The positive correlation between the MEP, MIP, FEV1 (L), and severe PA was found. FVC with sitting, FEV1 (L) with moderate PA, and FEV1/FVC (%) with PSQI, sitting with educational status were positively correlated (p<0.05). There was a negative correlation between the %MIP and a systolic blood pressure; MIP, MEP (% and cmH(2)O) with diastolic blood pressure (p<0.05), and a positive correlation between the %MEP and SpO(2) (p<0.05). Conclusion: As a result, respiratory function, PA, and the sleep quality of individuals with epilepsy were affected. Respiratory muscle training, PA programs, and behavioral changes should be added to the medical treatment programs of these individuals.Öğe Neurologic Soft Signs in Behcet Disease(Lippincott Williams & Wilkins, 2010) Okuyucu, Esra E.; Balci, Didem D.; Balci, Ali; Duman, Taskin; Akcin, EbruBackground: Patients with Behcet disease have an excess of minor neurologic abnormalities (neurologic soft signs). Objective: (a) To investigate the neurologic soft signs (NSS) in Behcet disease (BD) patients who had no neurologic symptoms, by using the neurologic evaluation scale (NES). (b) To evaluate the effect of silent infarction on NES scores in BD patients. Methods: Thirty six BD patients without neurologic symptoms and 36 healthy controls were included M the study. NSS were assessed with the NES. Cranial magnetic resonance imaging was conducted to determine the presence of silent cerebral infarcts. Results: Patients with BD had significantly higher scores overall and on each subscale (except for subscale others) of the NES than the control group's. Tandem walk, adventitious overflow, tremor, graphesthesia, fist edge palm test, Ozeretski test, finger thumb opposition, mirror movements, extinction, synkinesis, convergence, finger nose test, glabellar reflex, grasp reflex, and suck reflex were also significantly higher in patients with BD than in the healthy control group. There were no significant differences in the total NES scores, total subscale scores and each of the NES items between BD patients with silent infarction and those without infarction. Conclusion: Early diagnosis of neurologic involvement in BD is important and the NES is a useful instrument for detecting subchnical neurologic involvement in BD patients.Öğe Probability of stroke in the couples of stroke patients; using Framingham Stroke Risk Profi?le(Turkish Society of Cerebrovascular Diseases, 2012) Duman, Taşkin; Okuyucu, Esra E.; Melek, Ismet M.; Yilmazer, Serkan; Inandi, Tacettin; Mengüllüo?lu, NecdetINTRODUCTION: Environmental and personal factors may be of importance for stroke risk. We determined the stroke risk factors among the stroke patients' couples and controls. MATERIAL AND METHODS: A prospective study was conducted on 221 participants (71 stroke patients, 71 stroke patients' couples, 79 controls) aged more than 54 years. Framingham Stroke Risk Profile was used to measure the stroke risk. RESULTS: In subjects aged 54 years and older, became a couple of stroke patient were not associated with an increased risk of stroke. CONCLUSION: In this study, environmental and personal factors were an independent risk factor for stroke in stroke patients' couples and controls older than 54 years.Öğe Restless legs syndrome in a person with Fahr's disease(Riyadh Armed Forces Hospital, 2009) Okuyucu, Esra E.; Tunc, Tugba; Karazincir, Sinem; Duman, Taskin[Abstract Not Available]Öğe Reversible parkinsonism with oxcarbazepine use(Elsevier Sci Ltd, 2009) Okuyucu, Esra E.; Duman, Taskin; Akcin, Ebru[Abstract Not Available]