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    Effect of phosphodiesterase-5 inhibitor on hearing
    (Cambridge Univ Press, 2009) Okuyucu, S.; Guven, O. E.; Akoglu, E.; Ucar, E.; Dagli, S.
    Objective: Following a report of sudden hearing loss in a patient taking phosphodiesterase type 5 inhibitor, and a Food and Drug Administration announcement concerning this class of drugs, a study was planned to investigate if ototoxicity occurs in patients using phosphodiesterase 5 inhibitor for erectile dysfunction. Methods: Eighteen patients with erectile dysfunction who had been using phosphodiesterase 5 inhibitor were included in the study. Audiometric tests were performed on all patients, between the frequencies 250 and 16 000 Hz, before and 1, 5 and 72 hours after drug ingestion. Results: Four patients showed a unilateral threshold decrease compatible with ototoxicity criteria; this change was reversible. A statistically significant difference in pre- versus post-drug hearing thresholds was observed in the right ear at 10 000 Hz (p = 0.008). There were no statistically significant hearing threshold differences at any other frequencies (p > 0.05). Conclusion: Although temporary ototoxicity was noted in four patients, we could not find any permanent, deleterious effect of phosphodiesterase type 5 inhibitor on hearing thresholds.
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    Inverted papilloma with squamous cell carcinoma
    (Springer, 2012) Ozgur, T.; Toprak, S.; Atik, E.; Gokce, H.; Okuyucu, S.
    [Abstract Not Available]
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    Öğe
    Otoplasty: results with anterior scoring of the helical cartilage and conchal resection
    (Galenos Yayincilik, 2009) Okuyucu, S.; Mutlu, O.; Akoglu, E.; Daglu, A. S.
    Objectives: The aim of this study is to evaluate results of anterior surface incision of antihelix, suturation and conchal cartilage resection for prominent ear. Methods: Seven ears of four patients were included into the study who were operated between 2004 and 2006. The formation of antihelix was obtained with incision techniques whereas suturation is used for stabilization. Conchal hypertrophia was corrected with cartilage resection. The evaluation of the results was achieved with preoperative and postoperative photographs. Results: Antihelix development failure was seen in three ears whereas conchal wideness or deep conchal bowl causes additional problem in four ears. Postoperative hematom was the only complication which was observed in two patients. A pleasant cosmesis was obtained in all patients except one patient in whom the correction of the ears were asymmetric. Conclusion: Anterior cartilage incisions to maintain antihelix and conchal cartilage resection to reduce hypertrophy gives pleasant cosmetic results with reduced complication risks.