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    Association Between Prostate Volume and Red Cell Distribution Width
    (Wiley, 2014) Zorba, Orhan U.; Uzun, Hakki; Onem, Kadir; Cetinkaya, Mehmet; Rifaioglu, Murat; Akca, Nezih
    ObjectivesTo evaluate relation between red cell distribution width (RDW) and benign prostatic hyperplasia (BPH). MethodsThe overall study population consisted of 942 men with lower urinary tract symptoms (LUTS), ranging in age from 60 to 85years old. Patients with disorder or medication that can influence lower urinary tract or erythrocytes were excluded from the study. The relationship between RDW, white blood cell (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and prostate volume, International Prostate Symptom Score (IPSS) were assessed with multivariate linear regression model. Patients were analyzed in four groups stratified according to the quartiles of prostate volume. The one-way analysis of variance (anova) was used to compare RDW, WBC CRP, and ESR between different quartiles of prostate volume. ResultsA graded and independent association of RDW with the prostate volume was identified (P=0.001). RDW was significantly associated with prostate volume in multivariate linear regression model that was adjusted for age and hemoglobin. IPSS was significantly correlated with RDW, CRP and ESR. However significance was lost after adjustment for age and prostate volume. The RDW was significantly associated with the surgical treatment in the multivariate linear regression model that was adjusted for age and prostate volume. ConclusionsA correlation between an increased RDW and prostate volume was suggested by the new data from this study. This relation may be a consequence of inflammatory stress arising from BPH. The significant association between the easy, inexpensive RDW may provide a rational basis to include the RDW in algorithms for surgery risk prediction.
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    Villous adenoma of the urinary bladder: rare location
    (Termedia Publishing House Ltd, 2012) Atik, Esin; Akansu, Bulent; Davarci, Mursel; Inci, Mehmet; Yalcinkaya, Fatih; Rifaioglu, Murat
    Villous adenomas are common lesions of the gastrointestinal tract but they are rarely located in the urinary tract including the urinary bladder. There are a few case reports and series in the literature. Here we report a 43-year-old male patient who had a polypoid lesion located on the left lateral wall of the urinary bladder. Transurethral resection was performed. The diagnosis was 'villous adenoma of urinary bladder' with clinical and histopathological findings. Villous adenomas are mostly seen in elderly males. The coexistence of villous adenoma with adenocarcinoma, squamous cell carcinoma, and urothelial carcinoma was observed but there is not clear evidence about progression to carcinoma, in spite of its colonic counterpart. Generally complete surgical resection is accepted as curative but there are no exact data about follow-up and recurrence. By presenting this case, we aim to emphasize that it is a rare but important lesion because of coexistence with malignancies and uncertain malignant potential.