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    Nebulized salbutamol for asthma: Effects on serum potassium and phosphate levels at the 60 min
    (Elsevier Doyma Sl, 2013) Sahan, M.; Yilmaz, M.; Gokel, Y.; Erden, E. S.; Karakus, A.
    Objective: We conducted this prospective study to expand available information in relation to serum phosphate levels in treatment of acute asthma. A beta-adrenergic agonist, salbutamol, was used for this purpose. Material and methods: Twenty-six patients who met the inclusion criteria as; age over 16 years, asthma history, and an acute exacerbation were included. Serum blood urea nitrogen, creatinine, glucose were within normal limits in all the patients. None of the patients were on chronic theophylline therapy. Baseline serum phosphate and potassium levels were measured. Nebulized salbutamol (2.5 mg) was used three times at every hour. After 60 min, serum phosphate and potassium levels were measured. Results: Serum phosphate levels decreased from 3.7 +/- 0.9 mg/dL (baseline) to 3.6 +/- 0.9 mg/dL at 60 min. This decrease was not statistically significant (p=0.373). Serum potassium levels decreased significantly (p < 0.001) from 4.6 +/- 0.7 mmol/L (baseline) to 4.3 +/- 0.7 mmol/L (60 min). Conclusion: Administration of nebulized salbutamol during the emergency treatment of acute exacerbation of asthma is not associated with a statistical decrease in serum phosphate. There was significant hypokalemia. This study indicates that a further study is needed to elucidate the clinical significance of nebulized salbutamol on serum phosphate. (c) 2012 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L. All rights reserved.
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    Triggers for attacks in familial mediterranean fever: Are there any regional or ethnic differences?
    (Acta Medica Mediterranea, 2014) Huseyin, Cebicci; Aykac Cebicci, M.; Sahan, M.; Gurbuz, S.; Karaca, B.; Karakus, A.; Tomruk Sutbeyaz, S.
    Introduction: Familial Mediterranean Fever (FMF) is an autosomal recessive disorder which is characterized by recurrent episodes of fever and inflammation including peritonitis, synovitis and pleuritis accompanied by pain.The present study was conducted with the aim to determine the triggering factors of FMF and investigate whether there are any differences between two regions with different geographical characteristics with respect to triggers of attacks in FMF patients admitting to the emergency room with an episode of abdominal pain. Materials and methods: The study was planned as a prospective, two-site study to be conducted in Kayseri and Hatay. Triggers of attacks were investigated for patients previously diagnosed with FMF who admitted to the emergency room with an episode of abdominal pain. Results: A total of 75 patients were enrolled in the study including 40 in Kayseri group and 35 in Hatay group. Kayseri group had a predominance of female patients and Hatay a predominance of male patients. Emotional stress, excessive physical activity, menstruation and exposure to cold were found to trigger FMF-associated abdominal pain episodes in Kayseri group, whereas emotional stress and excessive physical activity were predominant triggers of attacks in Hatay group. Conclusion: FMF attacks were found to be associated with emotional stress and excessive physical activity in both study groups. Excessive physical activity, menstruation and exposure to cold were significantly more likely to trigger attacks in Kayseri group compared to Hatay group.
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    Öğe
    TRIGGERS FOR ATTACKS IN FAMILIAL MEDITERRANEAN FEVER: ARE THERE ANY REGIONAL OR ETHNIC DIFFERENCES?
    (Carbone Editore, 2014) Huseyin, Cebicci; Cebicci, Aykac M.; Sahan, M.; Gurbuz, S.; Karaca, B.; Karakus, A.; Sutbeyaz, Tomruk S.
    Introduction