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Yazar "Sangun, Ozlem" seçeneğine göre listele

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    Acitretin for Papillon-Lefevre syndrome in a five-year-old girl
    (Wolters Kluwer Medknow Publications, 2008) Bald, Didern Didar; Serarslan, Gamze; Sangun, Ozlem; Homan, Seydo
    [Abstract Not Available]
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    Assessment of biochemical bone markers of osteoporosis in children with thalassemia major
    (Bmc, 2022) Celik, Tanju; Sangun, Ozlem; Unal, Sule; Balci, Ali; Motor, Sedat
    Background Beta thalassemia major (beta-TM) is a common cause of skeletal morbidity and is associated with increased bone fracture risk, particularly in inadequately transfused children. The aim of this study was to investigate some potential biochemical markers as possible early predictors of BMD variations in children with beta-TM. Methods The study included 38 children with beta-TM and 40 sex-age matched controls. All patients were subjected to BMD assessment by dual-energy X-ray absorptiometry (DEXA). Serum beta-crosslaps (beta-CTx), osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B ligand (RANKL), urinary deoxypyridinoline (DPD) and ferritin levels were compared between the groups. Results Serum OPG levels were significantly lower in thalassemic children than in controls. The mean ratio of RANKL/OPG was significantly higher in the thalassemic patients than in the control group. Osteoporosis was detected in 10 (3 female and 7 male) of 38 patients (26.3%) according to the femur Z score and in 6 of them (4 male and 2 female) (15.8%) according to the spine Z score. Conclusions Serum OPG concentrations can be used as a biochemical marker in screening patients with beta-thalassemia major for the development of osteoporosis.
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    Dimensions of internal jugular veins in Turkish children aged between 0 and 6 years in resting state and during Valsalva maneuver
    (Elsevier Ireland Ltd, 2007) Karazincir, Sinem; Akoglu, Ertap; Balcı, Ali; Sangun, Ozlem; Okuyucu, Semsettin; Ozbakis, Cagla; Karazincir, Olgun
    Objective: We aimed to establish the values of the internal jugular vein (IJV) sizes in Turkish children aged between 0 and 6 years. Methods: Ninety-four normal children included in this study. All of the children were imaged by ultrasonography (USG) at the level of the cricoid cartilage. The maximal antero-posterior (AP) and transverse (T) diameters of the IJV were measured during regular breathing and Valsalva maneuver. Results: The mean transverse diameter of the right and left IJV were 8.11 +/- 3.01 and 7.64 +/- 2.68 mm in resting state. These values changed to 12.57 +/- 4.34 and 10.82 +/- 3.80 mm in Valsalva state, respectively. The AP diameters were found to be 5.43 +/- 2.07 for the right and 5.86 +/- 4.53 mm for the left IJV at rest. During VM, these values changed to 8.70 +/- 2.40 and 8.30 +/- 2.90 mm for the right and left IJV, respectively. There was no significant difference on the evaluation of the relationship between the right and left diameters of the IJV. While there were significant differences in sizes between the resting and Valsalva states. Also, the T diameter of the right IJV during Valsalva state was greater than those of the left. There were significant correlations between the diameters of the IJV and the age, weight and height of the children. Conclusion: The results we obtained in this study may be important in an attempt of intravascular intervention to IJV. These values may also be important for the comparison with the IJV sizes of the patients who have phlebectasia. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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    Iodine, copper, zinc, selenium and molybdenum levels in children aged between 6 and 12 years in the rural area with iodine deficiency and in the city center without iodine deficiency in Hatay
    (Aves, 2014) Celik, Tanju; Savas, Nazan; Kurtoglu, Selim; Sangun, Ozlem; Aydin, Zeki; Mustafa, Didin; Ozturk, Oktay Hasan
    Aim: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiencies which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). Material and Methods: This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanisma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. Results: Iodine deficiency was found with a severe (5%), moderate (18.4%) and mild degree (43%), respectively in the village of Tanisma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p < 0.001). A significant correlation was found between the levels of iodine, selenium, zinc and molybdenum (p < 0.05). A moderately positive correlation was found between iodine and selenium (p < 0.001). A moderately positive correlation was found between iodine and zinc levels (p < 0.001) and a weak correlation was found between iodine and molybdenum (p < 0.01). No significant correlation was found between iodine level and copper level (p > 0.05). Conclusions: Selenium and zinc deficiency may accompany iodine deficiency. Selenium and zinc deficiency should be considered in individuals who are found to have iodine deficiency especially in endemic goitre regions.
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    Macrocephaly and bitemporal arachnoid cysts not associated with glutaric aciduria type I in a child
    (Turkish Neurosurgical Soc, 2008) Serarslan, Yurdal; Melek, Ismet Murat; Sangun, Ozlem; Akcora, Buelent; Akdemir, Goekhan
    A 45-month-old child who had bitemporal arachnoid cysts and macrocephaly unrelated to glutaric aciduria type 1 (GA 1) was reported. The patient was admitted to the emergency unit after head trauma at 11 months of age. CT and MRI showed bitemporal arachnoid cysts (BACs). Acylcarnitine profile was normal in serum using tandem mass spectrometry. Urine and blood screening tests were within normal range for metabolic disorders. There were no unusual organic acids in urine and blood samples. No additional clinical findings of metabolic disorders such as GA I developed during follow-up. The majority of children affected with GA 1 have macrocephaly and BACs on CT or MRI. These signs should alert neurosurgeons to the possibility of GA 1. Neurosurgeons evaluating patients with head trauma or suspected non-accidental head injury should include GA 1 in the differential diagnosis of BACs associated with macrocephaly, and an evaluation should be performed.
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    The prevalence and significance of incidental middle ear and mastoid cavity abnormalities on MRI in a pediatric population
    (Elsevier Ireland Ltd, 2008) Balcı, Ali; Sangun, Ozlem; Okuyucu, Semsettin; Karazincir, Sinem; Akoglu, Ertap; Altintas, Yasemin; Egilmez, Ertugrul
    Objective: The purposes of this study were to determine the prevalence of abnormalities in the middle ear and mastoid cavity on the magnetic resonance imaging (MRI) in children and correlate the results with clinical. data, tympanometric findings and paranasal sinus changes. Materials and methods: A total. of 85 consecutive pediatric patients for suspected non-inflammatory intracranial pathologies were prospectively examined. MRI was conducted for the suspected intracranial pathology. All patients were also examined by an otolaryngologist for otologic pathologies. A tympanometry examination was performed in patients prior to MRI scan. Results: In 23 (27.1%) of 85 (39 mates, 46 females) children, MRI demonstrated middle ear and/or mastoid cavity abnormalities. MRI abnormalities of the middle ear and/or mastoid cavity were correlated with clinical. data and tympanometric findings. Conclusions: Incidental abnormal signal intensities in the middle ear and/or mastoid cavity are frequent in children, especially in first years of life. MRI will demonstrate incidental middle ear and mastoid cavity abnormalities seems to have clinical significance. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
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    Probable montelukast-induced hepatotoxicity in a pediatric patient: case report
    (K Faisal Spec Hosp Res Centre, 2008) Incecik, Faruk; Onlen, Yusuf; Sangun, Ozlem; Akoglu, Sabahat
    [Abstract Not Available]
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    Probable montelukast-induced hepatotoxicity in a pediatric patient: Case report [3]
    (King Faisal Specialist Hospital and Research Centre, 2007) Incecik, Faruk; Onlen, Yusuf; Sangun, Ozlem; Akoglu, Sabahat
    [No abstract available]
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    Violence, Psychological Features, and Substance Use in High School Students in Hatay: a Cross-sectional Study
    (Aves Yayincilik, Ibrahim Kara, 2009) Inandi, Tacettin; Ozer, Cahit; Akdemir, Asena; Akoglu, Sabahat; Babayigit, Cenk; Turhan, Ebru; Sangun, Ozlem
    Objectives: To evaluate the prevalence of substance use among high school students and to examine the relationship between substance use and violence and psychological features. Patients and Methods: A cross-sectional study was carried out in 23 high schools in Hatay in 2006 using a questionnaire consisted of General Perceived Self-Efficacy Scale, Rosenberg Self-Esteem Scale, Multidimensional Scale of Perceived Social Support, and State-Trait Anxiety Inventory. Results: A total of 1629 students were given study questionnaire. Lifetime substance use prevalence was 38.8 for cigarette smoking, 30.5 for alcohol use, 30.1 for being drunk, 13.9 for regular smoking, 7.1 for volatile substance use, 1.1 for marijuana use, 0.8 for drug use such as heroin, ecstasy, and cocaine. Anxiety scores were higher in smokers while self esteem and self efficacy scores were higher in alcohol users. Exposure to physical violence and use of physical violence within the last year were higher in smokers and in all substance users. Conclusion: Cigarette, alcohol and volatile substances were frequently used among adolescents. The results show that high anxiety is related with smoking, high self esteem and self efficacy are related with alcohol use. Substance use is associated with exposure to and use of violence.

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