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Öğe Assessment of elongated styloid process with cone-beam computed tomography in western part of the Black Sea region(2019) Serindere, Gözde; Bayrak, SevalObjective: This study aimed to evaluate the prevalence and morphology of elongated styloid process and its relation to gender, age and location in Turkish population. Materials and Methods: Cone beam computed tomography (CBCT) images of 170 patients were evaluated. Age and gender of the patients who were included in this study were recorded. Morphology of elongated styloid process was analyzed and prevalence was determined. Mean lengths of elongated styloid processes were measured. Results: Elongated styloid process was observed in 68 (40%) of 170 patients (340 styloid processes). Mean lengths of elongated SP were 35.25 mm. Elongation was observed in right side in 4 (2.4%) of 170 patients while was observed in left side in 28 (16.5%) patients and it was seen bilaterally in 36 (21.2%) patients. In our study, the most frequent morphology was observed as Type 1. The most common calcification pattern was Type D. Conclusion: In this study, CBCT was presented as an alternative method to panoramic radiographs for the measurement and the assessment of the styloid process.Öğe COMPARISON OF MANUAL AND SEMIAUTOMATIC SEGMENTATION METHODS FOR CALCULATING FRONTAL AND SPHENOID SINUS AREA AND VOLUME USING OF COMPUTED TOMOGRAPHY(2021) Belgin, Ceren Aktuna; Serindere, GözdeObjective: To compare the effectiveness of the manual and semi-automatic segmentation modules of the third-generation software used in computedtomography (CT) images in calculating frontal sinus (FS) and sphenoid sinus (SS) areas and volumes.Methods: CT images of 200 patients (96 female, 104 male) between the ages of 19 and 73 years (mean 37.38 ± 16.32 years) were randomly selected.Volume and area of FS and SS were segmented manually and semi-automatically using InVesalius 3.1.1 software (CTI, Campinas, São Paulo,Brazil).Results: There was a statistically significant difference was found the main SS area in manual mode and semi-automatic mode as 4.80 ± 1.86 $cm^2$ and 4.84 ± 1.83 $cm^2$, respectively. The main SS volumes were in manual mode and semi-automatic mode as 8.44 ± 3.55 $cm^3$and 9.62 ± 3.21 $cm^3$, respectively. The main FS volumes were in manual mode and semi-automatic mode as 5.32 ± 2.04 $cm^3$ and 6.65 ± 2.70 $cm^3$, respectively. There was a statistically significant difference was found between manual mode and semi-automatic mode in volume calculation (p<0.05).Conclusion: It was seen that the values measured in both segmentations are close to those presented in the mean literature data, however, whenusing the semi-automatic segmentation module, it should be ensured that the formations other than the structure to be evaluated are not included inthe measurement.Öğe Evaluation of changes in nasopalatine canal morphology according to dentition status by computed tomography(Kocaeli Üniversitesi, 2020) Aktuna Belgin, Ceren; Serindere, GözdeObjective: The nasopalatine canal (NPC) is one of the important anatomic structures in anterior maxilla. The aim of this study was to evaluate thechanges in NPC morphology according to dentition status in the maxillary anterior region by computed tomography (CT).Methods: Computed tomography images of 100 patients were screened retrospectively. Images were divided into two groups by dental status: anedentulous group (EG) of 50 patients who have edentulous premaxilla and a control group (CG) of 50 patients who have all incisor teeth in thepremaxillary region. After recording the age, sex, and dentition status of the patients, the NPC diameter, NPC length, incisive foramen (IF) diameter,and angle between the NPC and palatine bone were measured in sagittal sections, and the number of NPCs was determined in axial sections.Results: There was no significant difference between NPC angle and dentition status (p=0.151). The NPC diameter was significantly higher in theEG (p=0.002), as was the IF diameter (p=0.041). In addition, NPC length was significantly higher in the CG (p<0.001). A statistically significant andnegative correlation was found between age and NPC length (p<0.001), and a positive correlation was found between age and NPC diameter(p=0.004). In addition, no statistically significant difference was found between sex and other parameters (p>0.05).Conclusion: The NPC length and diameter vary according to the age and dentition status of the patient. Changes in this anatomic structure should beevaluated pre-operatively in elderly patients by three-dimensional radiographic evaluation.Öğe Evaluation of error types and quality on panoramic radiography(International Association for Dental Research, 2019) Aktuna Belgin, Ceren; Serindere, GözdeAim: The aim of this study was to investigate the prevalence of panoramic radiographic errors and to evaluate the correlation between age and panoramic radiographic error types. Methodology: A total of 500 panoramic radiographs (259 male, 241 female) which had been taken for various reasons were randomly selected from the archive of our dentomaxillofacial radiology department. Patients were divided into six age groups and by sex. The assessed errors included the tongue not in contact with the palate, slumped position, patients not biting on bite block, patient movement, the chin tipped high, the chin tipped low, the patient positioned forward, the patient positioned backward, patient’s head turned to one side, foreign bodies in the image, exposure errors, positioning error of the lips and missing image. The quality of each radiograph was rated as excellent, diagnostically acceptable or unacceptable. Results: One or more errors were detected in 317 (63.4%) of the 500 panoramic radiographs, while no error was found in 183 (36.6%) of the images. It was observed that the most common error type was the slumped position (13.2%). All of the panoramic radiographs were evaluated according to the quality criteria: only 15% of the images were classified as “excellent”, 48.2% were rated “inadequate for diagnosis” and 36.8% were graded “adequate for diagnosis”. It was recorded that “slumped position” and “patient movement” errors were statistically significant in >56 years (p<0.05). Conclusions: Patients can be protected from unnecessary radiation exposure by investigating the causes of panoramic radiographic errors and by providing appropriate training to technicians.Öğe Evaluation of third molar agenesis associated with hypodontia and oligodontia in Turkish pediatric patients(İstanbul Üniversitesi, 2020) Tekbaş Atay, Meltem; Özveren, Neslihan; Serindere, GözdePurposeTo evaluate the association between third molar (M3) agenesis and hypodontia andoligodontia in pediatric patients by using panoramic radiography.Materials and MethodsPanoramic radiographs of 1,471 patients (899 females; 572 males) and 5,884 teethwere retrospectively evaluated. The age and gender of the patients were recorded.Patients ages 9-15 years old were included in the study. The mean age was 12.76.The agenesis of M3 teeth and the relationship between M3 agenesis and hypodontiaand oligodontia were recorded according to findings from the upper and lower jaw,in both the right and left locations, along with the number of M3 with agenesis. Datawere analyzed using chi-square and McNemar tests (p<0.05).ResultsA total of 1,319 (89.7%) patients had all M3 teeth present in the mouth, while theother 152 (10.3%) had congenital agenesis in one or more teeth. The number ofteeth in which M3 agenesis was seen, in order of the number of missing M3 teeth,the percentages were 2.6% for one, 2.4% for two, 1.0% for three and 4.3% forfour missing teeth.Hypodontia was detected in 37 patients and oligodontia wasdetected in 3 patients.ConclusionThe prevalence of M3 agenesis varies from one population to another. Two of thedental anomalies associated with M3 agenesis are hypodontia and oligodontia. Inthis study, M3 agenesis varied in terms of region and gender; hypodontia was alsosignificantly higher in patients with missing mandibular M3.Öğe The evaluation of visibility of mandibular anatomic landmarks using panoramic radiography(International Association for Dental Research, 2019) Serindere, Gözde; Aktuna Belgin, CerenAim: The mandibular canal, mandibular foramen, mental foramen, and incisive canal are important anatomical structures for dental surgery. The aim of this study was to evaluate the visibility of these important landmarks in different age groups and to compare the visibility in the dentulous group with the edentulous group on panoramic radiographs. Methodology: Panoramic radiographs of 500 patients (237 males and 263 females; mean age:39.2) were evaluated for this study; the visibility of their anatomical landmarks was analyzed, and scores were noted.The data obtained were analyzed using the SPSS 21 package program.The value of p<0.05 was considered statistically significant. Results: The mandibular canal, mandibular foramen, mental foramen, and incisive canal were visible in 89.8%, 88%, 80.6%, and 12.8%of all radiographs, respectively.Twenty-three(4.6%) patients had total tooth loss.The visibility of the anatomical landmarks were most clearly observed in groups below 25 years old. Conclusions: Panoramic radiographs provide useful information on the visibility of anatomical landmarks. However, using 3D imaging methods before surgical procedures will provide more accurate results.Öğe Hatay ilinde oral premalign lezyonların prevalansı: retrospektif bir çalışma(2020) Serindere, Gözde; Aktuna Belgin, Ceren; Gürsoy, Didar; Orhan, KaanBu çalışmanın amacı, 2017 ve 2019 yılları arasında Patoloji Anabilim Dalı'na başvuran hastalarda oral premalign lezyonların(OPL) prevalansını değerlendirmektir. Patoloji rapor arşivinde histopatolojik olarak OPL olduğu doğrulanmış toplam 194 hastageriye dönük olarak incelendi. Bunlardan 82'si (% 42,3) erkek, 112'si (% 57,7) kadındı. Cinsiyet ve yaş bilgisi tıbbi kayıtlardan eldeedildi. Patolojik sonuçlara göre OPL'ler sınıflandırıldı. 194 hastada OPL bulundu. 112 (% 57,7) kadın, 82'si (% 42,3) erkekti. Yaşdağılımına göre 10-20, 21-30, 31-40, 41-50- 51-60, 61-70, 71-80 ve 80 yaş üstü hasta sayıları 1 (% 0,5), 13 (% 6,7), 25 (% 12,9), 36(% 18,5), 50 (% 25,8), 35 (% 18,1), 20 (% 10,3) ve 14 (% 7,2) idi. En sık görülen premalign lezyon liken planus (% 50,6) olarakbulundu. Ağız boşluğunda malignite olasılığını ekarte etmek için biyopsi yapılmalıdır. OPL'lerin erken teşhisi tedavi için önemlidir.Öğe Investigation of bifid mandibular canal frequency with cone beam computed tomography in a Turkish population(2017) Serindere, Gözde; Gündüz, Kaan; Bulut, ElifObjectives:It is important to know anatomic location and variations of the mandibular canal (MC) for surgical treatment onmandible such as implant operations, impacted molar tooth extraction and sagittal split ramus osteotomy. The purpose of our studyis to determine the configuration and incidence of bifid mandibular canal (BMC) using cone beam computed tomography (CBCT). Methods: CBCT scans of 2000 patients were retrospectively analysed. Age and gender of the patients who were includedin this study were recorded. BMC was subdivided, frequency was determined. Measurements of mean lengths, superior andinferior angles were performed. The all measurements were performed by one observer in 3 times at intervals of one weekto confirm intra-observer reliability. SPSS 21 (Statistical Package for Social Science 21) was used for statistical analysis. It wasbenefited from Chi-square test to investigate qualitative observation and from T test and one-way analysis of variance forinvestigation of quantative observation. Differences were considered significant at pÖğe Investigation of the Effect of Linoleic Acid on Vascularization in Experimentally Induce Zoledronic Acid-Related Osteonecrosis in Rats(2021) Yurtal, Ziya; Serindere, Gözde; Belgin, Ceren Aktuna; Takcı, LutfiBisphosphonate-related osteonecrosis of the jaw (BRONJ) is an increasingly common pathological condition whose pathophysiology is not fully understood and can be difficult to manage. The unique biological effects of conjugated linoleic acid (CLA) include angiogenic, anticarcinogenic, antiatherosclerotic, antioxidative, immunomodulative and antibacterial effects. The aim of this study is to compare the osteonecrosis areas created by tooth extraction with the control group using scanning electron microscopy (SEM) after the administration of zoledronic acid (ZA), CLA and a combination of both in the rat jaw. A total of 50 Wistar Albino male rats weighing 400-450 grams were used. The groups were randomly divided into 5 groups: the control group, the sham group, the group that received ZA, the groups that received CLA with ZA (100 mg / kg and 200 mg / kg), and the study lasted a total of 10 weeks. Regardless of the use of ZA, it was observed by SEM that vascularization was impaired in all groups with tooth extraction. Neovascularization did not occur in the groups where CLA was applied, regardless of the dose. It was concluded that SEM analysis and corrosion casts technique can be considered as an alternative method in such studies due to its accessibility and low cost in observing dental vascularization. However, no definite conclusion could be reached about the neovascularization efficiency of CLA within the period evaluated after tooth extraction.Öğe An Investigation of the Relationship Between Schneiderian Membrane Thickness and Sinus Floor Cortication through Cone-beam Computed Tomography(2020) Bayrak, Seval; Ustaoğlu, Gülbahar; Serindere, Gözde; Kocasaraç, Hüsniye DemirtürkAim: In this study, we aimed to investigate the relationship between sinus floor cortication (SFC)and Schneiderian membrane thickness (SMT) through cone-beam computed tomography (CBCT)images.Materials and Methods: A total of 292 maxillary sinuses of 146 patients (61 males, 85 females)who underwent a CBCT scan for dental implant treatment were evaluated. SFC was classifiedas follows: type-1: sinus floor exhibiting similar or higher density than the surrounding corticalareas, type-2: sinus floor exhibiting lower density than the surrounding cortical areas, type-3:sinus floor exhibiting no cortical bone, and type-4: sinus floor exhibiting fusion of sinus floor boneand native crestal bone. We also investigated the relationship between the SFC types and SMTsmeasured from the highest border of the membrane to the sinus floor on cross-sectional images.Results: Type-1, type-2, type-3, and type-4 SFC were seen in 114, 102, 48, and 28 cases, respectively. The Schneiderian membrane was found to be thinner in type-1 SFC than in type-2 SFC. Nosignificant difference was found between type-3 and type-4 SFC in terms of SMT.Discussion and Conclusion: Evaluation of SFC and SMT using CBCT can provide informationabout implant stability and survival in treatment after sinus grafting. Although type-1 SFC is favorable for implant placement, it may also be associated with an increased risk of membraneperforation.Öğe Kronik böbrek yetmezlikli hastalarda oral bulgular: 2 olgu sunumu(2018) Serindere, GözdeKronik böbrek yetmezliği (KBY) çeşitli nedenlere bağlı olarak böbrek fonksiyonlarının tam olarak yerine getirilemediği bir hastalıktır. Günümüzde böbrek hastalıklarının sıklığı oldukça artmış olup, bu hastalar dişhekimleri açısından önemli bir hasta grubunu oluşturmaktadır. Kullanılan ilaçlar, diyaliz tedavisi intraoral dokuları etkileyebilir. Bu olgu sunumunda amaç kronik böbrek yetmezliğinin intraoral dokular üzerindeki etkisini ve dişhekimleri açısından önemini vurgulamaktır.Öğe Prevalence and characteristics of pneumatized articular eminence on panoramic radiographs: a retrospective study and literature review(Kırıkkale Üniversitesi, 2019) Serindere, Gözde; Aktuna Belgin, CerenObjective: Pneumatized articular eminence (PAE) is an air filled cavity in temporal bone. The aim of this research was to evaluate the prevalence and characteristics of PAE using panoramic radiograhy. Material and Methods: The panoramic radiographs of 1000 patients were analyzed to describe prevalence and characteristics of PAE. Patients with PAE had a mean age of 35 years with a range of 19–85 years. Gender, age, localization and locularity of pneumatization were noted. Results: PAE was found in 19 (1.9%) patients with a mean age of 34.4. Twelve patients were female and seven patients were male. There was no statistically significant difference between gender and the presence of PAE (p>0.05). 12 unilateral and 7 bilateral cases were observed. Nine patients (47.4%) had PAE on the left side while three patients (15.8%) had PAE on the right side. Unilocular appearances were found in 7 patients (36.8%) while multilocular appearances were found in 11 patients (57.9%). One patient (5.3%) had both unilocular and multilocular types. Conclusion: Awareness for this anatomical variation is important for differential diagnosis from other lesions and also for planning temporomandibular joint surgery. Because of fragile structure of bone with PAE, the surgeons should be careful during temporomandibular joint operations.