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    A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening
    (Springer Heidelberg, 2011) Silfeler, Dilek B.; Tandogan, Bulent; Ayvaci, Habibe; Silfeler, Ibrahim; Yenidede, Ilter; Dayicioglu, Vedat
    We compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming. A total of 218 patients were enrolled to receive between one and three treatments according to physicians' options. The end points were: (1) vaginal delivery or Bishop score a parts per thousand yen8 at the end of 12 h, (2) vaginal delivery by 12 h or difference a parts per thousand yen4 between the initial and 12th hour Bishop scores. Statistical analyses were performed with ANOVA, Krustal Wallis, Scheffe, chi A(2), Fisher, Advanced chi A(2), and Kolmogorov-Smirnov tests. Tukey's HSD was used as a post hoc test. Misoprostol showed statistical significance for the rate of vaginal delivery < 12 h, a parts per thousand yen8 Bishop score at the end of 12 h, and cervical change of a parts per thousand yen4 Bishop scores within 12 h (p = 0.013). Comparison between cases Bishop score < 4 showed that misoprostol is more effective than dinoprostone and oxytocin. Considering Bishop score = 0 cases we calculated no statistical significance.
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    Menopausal cardiomyopathy: Does it really exist? A case-control deformation imaging study
    (Wiley, 2014) Kurt, Raziye Keskin; Nacar, Alper B.; Guler, Ayse; Silfeler, Dilek B.; Buyukkaya, Eyup; Karateke, Atilla; Kurt, Mustafa
    Aim We aimed to evaluate and compare the left ventricular (LV) functions of pre- and postmenopausal women at similar ages with none of the known cardiovascular risk factors, by both conventional and advanced echocardiographic methods such as 2-D strain imaging via speckle tracking echocardiography. Methods The study population consisted of 40 healthy postmenopausal women aged 45-50 years and 40 healthy premenopausal women of the same age group. None of the subjects had any cardiovascular risk factors and were on hormone replacement therapy. LV strain and strain rate parameters were measured by 2-D strain imaging. The main outcome measure was effect of menopause on LV function. Results There were no significant differences between the pre- and postmenopausal groups with regard to conventional echocardiographic parameters. LV longitudinal strain and LV early diastolic strain rate values were significantly lower in the postmenopausal group when compared to the premenopausal group. Also, there was a significant negative correlation between LV global strain and serum follicle-stimulating hormone (r=-0.349, P=0.002). Conclusion Our study results demonstrated that healthy postmenopausal women had lower LV longitudinal strain values when compared to the healthy premenopausal women of the same age group by speckle tracking echocardiography.
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    Reference Values of Serum Cystatin-C for Full-Term and Preterm Neonates in Istanbul
    (All India Inst Medical Sciences, 2012) Dorum, Sevil; Silfeler, Ibrahim; Dorum, Bayram Ali; Silfeler, Dilek B.; Canbak, Yekta; Say, Aysu
    To determine the level and distribution of Cystatin C values in full-term and preterm healthy neonates for the purpose of diagnosis and follow-up of renal diseases of the neonates. Eighty-eight newborn infants, including 55 preterm and 33 term born in the authors' hospital having no urinary tract pathology, symptoms or signs during prenatal and postnatal follow-up, were studied . There were 25 neonates born between gestational wk of 28 and 32 (Group 1), 30 neonates born between gestational wk of 33-36 (Group 2) and 33 neonates born after gestational wk of 37 (Group 3). Average cystatin C values were determined to be 1.41 mg/l, 1.22 mg/l and 1.21 mg/l for Group 1, Group 2 and Group 3, respectively. Evalution of cystatin C can be effective for follow-up of renal pathologies, because it is not affected by gender, body weight and muscle mass and has a constant production rate.