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Öğe Cutaneous manifestations in brucellosis: A prospective study(Springer, 2007) Akcali, Cenk; Savas, Lutfu; Baba, Mete; Turunc, Tuba; Seckin, DenizBrucellosis remains an important public health problem in Turkey, just as it is in other regions of the world. This study was conducted to determine the types and rates of cutaneous lesions that occur in patients with brucellosis. Brucellosis was diagnosed by standard tube agglutination testing for Brucella antibodies at a titer of 1/160 or higher in the presence of compatible clinical findings. A total of 140 patients who had been given a diagnosis of brucellosis were prospectively observed in the dermatology clinic. Of these patients, 102 (72.9%) were female, with a mean age of 44.11 +/- 18.22 y, and 38 (27.1 %) were male, with a mean age of 46.44 +/- 14.58 y. The duration of symptoms was less than 2 mo (acute) in 75 patients (53.5%), from 2 to 12 mo (subacute) in 30 patients (21.4%), and longer than 12 mo (chronic) in 35 patients (25.0%). Cutaneous findings related to brucellosis were observed in 8 (5.71%) of the 140 cases. Maculopapular eruptions were observed in 2 patients (25%), erythema nodosum-like lesions in 2 (25%), psoriasiform lesions in 1 (12.5%), palmar erythema in 1 (12.5%), malar eruption in 1 (12.5%), and palmar eczema in 1 (12.5%). The investigators concluded that although cutaneous findings encountered in brucellosis are generally not specific to this disease, the presence of these findings may be useful in diagnosing brucellosis in persons who live in, or used to live in, endemic regions.Öğe Epiderniologic, clinical, and imaging findings in brucellosis patients with osteoarticular involvement(Amer Roentgen Ray Soc, 2006) Pourbagher, Aysin; Pourbagher, Mir Ali; Savas, Lutfu; Turunc, Tuba; Demiroglu, Yusuf Ziya; Erol, Ilknur; Yalcintas, DefneOBJECTIVE. The aim of this study was to assess the epidemiologic and clinical features, complications, imaging findings, and outcomes for brucellosis patients with osteoarticular involvement. SUBJECTS AND METHODS. This prospective study was performed over 4 years (December 2000-December 2004). The subjects were 251 Turkish patients (age range, 2-77 years) who were diagnosed with brucellosis during that period. Joint sonography, radiography, radionuclide bone scintigraphy, and MRI were performed in all patients with osteoarticular and spinal manifestations. RESULTS. The disease was acute in 92 patients (36.7%), subacute in 48 patients (19.1%), and chronic in 111 patients (44.2%). Sonography of the joints showed bursitis in 13 patients (5.2%). Radiography, MRI, and scintigraphy revealed 71 patients (28.3%) with sacroiliitis, 26 (10.4%) with spondylodiskitis, three (1.2%) with acute osteomyelitis, and one (0.4%) with avascular necrosis of the femoral head. All patients received combinations of either two or three antibiotics. Surgery was performed in three patients with spinal instability or radiculopathy. CONCLUSION. Brucellosis is endemic to some regions. MRI is the method of choice for diagnosing osteoarticular and spinal complications of human brucellosis, especially during the early phase. It is important to differentiate tuberculous spondylodiskitis from brucellar spondylodiskitis because proper treatment for each of these diseases can prevent complications. The radiologic findings for these two forms of spondylodiskitis are similar, so serologic testing for brucellosis is necessary in such cases.Öğe Fever of Unknown Origin Due to Left Atrial Myxoma(Lippincott Williams & Wilkins, 2006) Savas, Lutfu; Onlen, Yusuf; Kiziltan, Tarik; Pourbagher, Ali; Seyfeli, Ergun; Turunc, Tuba; Yalcin, FatihFever of unknown origin may present diagnostic and/or curative difficulties. Myxomas are one of the rare causes of fever of unknown origin. A 67-year-old man with a 4-month history of fever of unknown origin was admitted to our department. Physical examination revealed 38.4 degrees C axillary temperature and accentuated second heart sound in cardiac auscultation. Blood, urinary, and throat cultures were negative. Transesophageal echocardiography showed a left atrial mass partially prolapsing into the left ventricle during diastole. Left atrial mass was excised, and histological examination showed atrial myxoma. Fever resolved within 48 hours after the operation, and the patient was discharged from hospital with complete improvement.Öğe INCIDENCE AND RISK FACTORS FOR LOW LEVEL VIREMIA IN CHRONIC HEPATITIS B PATIENTS RECEIVING ANTIVIRAL TREATMENT(Lippincott Williams & Wilkins, 2023) Hasanoglu, Imran; Guner, Hatice Rahmet; Zerdali, Esra Yerlikaya; Tosun, Selma; Onlen, Yusuf; Yildirim, Figen; Turunc, Tuba[Abstract Not Available]
