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    Assessment of Gastroesophageal Reflux Disease in Chronic Obstructive Pulmonary Disease: Is Measuring Cardioesophageal Angle on Multidetector Computed Tomography Images Useful?
    (Bentham Science Publ Ltd, 2016) Unlu, Ebru; Ulasli, Sevinc S.; Kacar, Emre; Acay, Mehtap B.; Ozdinc, Serife; Atci, Nesrin; Balcik, Cinar
    We aimed to investigate whether there were any differences between patients with chronic obstructive pulmonary disease (COPD) and controls according to their cardioesophageal angles (COA) by Computed tomography (CT) and also the relationship between the degrees of COA and pulmonary function values in COPD patients. Degrees of COA were measured on curved oblique coronal CT images of 198 COPD patients with gastroesophageal reflux (GER) and 298 control subjects. A comparative analysis of COA values in two groups was performed and possible correlations between degrees of COA and pulmonary function parameters were evaluated. COA values were significantly higher in COPD patients compared to controls (p<0.001). The degrees of COA was negatively correlated with FVC and FEV1 values (% and L) in COPD patients (p< 0.001, r=-0.579; p<0.001, r=-0.64 and p<0.001, r=-0.65; p<0.001, r=-0.615, respectively). A positive correlation between age and COA was found in all the study population (p=0.002; r=0.134). A negative correlation between COA and BMI was found in COPD patients (p=0.037, r=-0.149). In conclusion, COPD patients have significantly increased COA value which is a predisposing factor for GER. Also, the association between obtuse COA and decreased levels of pulmonary function parameters in COPD patients may indicate reflux-induced bronchoconstriction and should be considered in COPD management as a non invasive indicator of reflux.
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    Öğe
    Association of breast arterial calcification and osteoporosis in Turkish women
    (Professional Medical Publications, 2015) Atci, Nesrin; Elverici, Eda; Kurt, Raziye Keskin; Ozen, Derya; Unlu, Ebru; Araz, Levent
    Objective: Breast arterial calcification (BAC), medial calcific sclerosis of small to medium-sized muscular arteries, is a benign finding of mammographic evaluation. Previous studies have shown the relationships between BAC and systemic disorders such as cardiovascular disease, diabetes mellitus and hypertension. The aim of this study was to determine the association between reduced bone mineral density and BAC. Methods: The study population consisted of 567 women who had both mammography and bone mineral density evaluation. BAC (+) and BAC (-) women were compared for age, body mass index, postmenopausal duration, number of deliveries, breastfeeding duration, DM, HT, lipid treatment, osteopenia, and osteoporosis. Results: BAC was seen in mammographic evaluation of 179 women and 388 subjects without BAC accepted as the control group. There was a statistically significant relationship between age, postmenopausal duration, number of deliveries, history of DM, HT, lipid treatment and BAC. While the prevalence of osteopenia was higher in control group (52.8%), the rate of osteoporosis (48.7%) was higher in group with BAC. Conclusion: There was statistically significant relationship between BAC and osteoporosis in postmenopausal women. Determination of BAC in routine screening mammography might be helpful in both identifying women with risk of cardiovascular disease and osteoporosis.