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Öğe Changes in liquid emptying in migraine patients: diagnosed with liquid phase gastric emptying scintigraphy(Wiley, 2012) Yalcin, H.; Okuyucu, E. E.; Ucar, E.; Duman, T.; Yilmazer, S.Gastric stasis is suspected mostly to be encountered during acute migraine attack. The aim of this study is to evaluate the liquid phase gastric emptying and motility in migraine patients in ictal and interictal periods in comparison to normal subjects with gastric emptying scintigraphy. Seven women with migraine and age, sex matched controls who applied to the Neurology Department from May 2009 to May 2010 were compared. Gastric emptying study with a standard liquid was performed one time in the non-migraineur group and two times in the migraineur group. Non-migraineur controls and migraineurs were compared. The mean T1/2 was longer in ictal period in migraineurs. The T1/2 of migraineurs interictally and the control groups were similar. The T1/2 of migraineurs ictally and migraineurs interictally were also compared. We also considered the percentage of the radioactive material remaining in the stomach. There were no significant differences between non-migraineurs and migraineurs interictally. However, increased amount of radioactive material remaining in the stomach was observed in migraineurs ictally. We concluded that the liquid emptying was delayed in spontaneous migraine attacks in migraine without aura, however in the interictal period the emptying of liquids did not differ between migraineurs and non-migraineurs.Öğe Contractility evaluation by 2 dimensional echocardiography and gated SPECT myocardial perfusion scintigraphy in hypertensive patients with clinical presentation of atypical chest pain(Lithographia, 2011) Yalcin, H.; Karayalcin, B.; Boz, A.; Talay, B.; Belgi, A.; Yalcin, F.Background: Hypertension (HT) is a growing health problem in the population and associated with increased cardiovascular event risk and mortality. In hypertensive patients, progressive left ventricular (LV) contractility deterioration is detectable by gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy(9). We planned this study to explore the agreement in ejection fraction (EF) determination between 2 dimensional echocardiography and gated SPECT analysis in selected group of patients with hypertension. Patients and Methods: We studied 26 consecutive patients (mean age 56.5 +/- 8.8 years; 6 men) with hypertension. Quantitative contractility analysis by both echocardiography and SPECT at rest was performed to investigate the agreement between two diagnostic tests. Results: EF at rest was greater than 55 % in all patients. All patients had a clinical presentation of atypical chest pain. Therefore, in addition to quantitative contractility analysis at rest by echocardiography and myocardial SPECT perfusion scintigraphy, we examined ischemia by stress induction and determined that 10 patients had ischemic finding (38.4 %). The mean value of EF calculated by echocardiography was 67.5 +/- 5.7 %, while EF by gated SPECT was 72.8 +/- 8.5 %. We documented an acceptable agreement in EF determination between these 2 diagnostic tests by meaningful correlation (r = 0.556, p = 0.003). There was no regional contractility deterioration despite existence of ischemia in 10 patients of the study group. Conclusions: We observed that both echocardiography and gated SPECT can be used for quantification of EF in the hypertensive patients with an acceptable agreement. Hippokratia 2011; 15 (1): 64-68Öğe AN EVALUATION OF THE OCCUPATIONAL EXTERNAL RADIATION EXPOSURE OF PERSONNEL IN NUCLEAR MEDICINE PRACTICES (2010-2020)(Oxford Univ Press, 2022) Sahmaran, T.; Atilgan, H., I; Nur, S.; Sahutoglu, G.; Yalcin, H.The aim of this study was to examine the radiation doses received by personnel working in the Nuclear Medicine Department between 2010 and 2020. The data obtained were compared with the dosages recommended by international authorities. The UNSCEAR 2008 report stated that the worldwide annual average effective dose to which personnel were exposed when monitored between 2000 and 2002 was 0.70 and 1.40 mSv, respectively. In this report, 0.7 mSv refers to the dose of all monitored personnel, and 1.4 mSv refers to the dose above the detection limit. In this study, the annual average effective dose value for personnel exposed to radiation was calculated as 1.65 mSv. This value represents the dose above the detection limit. Although the individual dose results are below the recommended annual dose limit, it should not be forgotten that more effort should be made to reduce radiation doses using the as low as reasonable achievable principles.Öğe Is there a relation between Helicobacter pylori infection and gastroesophageal reflux in childhood?(Springer, 2011) Gunay, E. Ceylan; Yalcin, H.[Abstract Not Available]Öğe Left ventricular wall function abnormalities in patients with ankylosing spondylitis evaluated by gated myocardial perfusion scintigraphy(Elsevier Science Inc, 2011) Yalcin, H.; Guler, H.; Gunay, E.; Yeral, N.; Turhanoglu, A.; Bolac, E.; Yalcin, F.Background: Ankylosing spondilitis (AS) is a chronic inflammatory disease with prominent inflammation in joints and extraarticular organs. AS patients have approximately two times more risk of mortality than the normal population. One reason for this increase in mortality is increased cardiovascular risk. In this study, we have aimed to evaluate myocardial perfusion and left ventricular function using Tc-99m-MIBI gated myocardial perfusion single photon emission computed tomography (SPECT). Material and methods: The study group consisted of 28 AS patients (19 men, 9 women), and mean age 39.46 +/- 10.98 years. All patients underwent Tc-99m-MIBI gated myocardial perfusion SPECT with the same day protocol. Results: We detected various risk factors including smoking habits in 12, family history of cardiovascular disease in 12, hypertension in 3, hyperlipidemia in 9 patients. We performed a myocardial perfusion SPECT for each patient and found normal perfusion pattern in SPECT images. Out of 28 patients, eight patients had normal perfusion but wall motion abnormalities. Conclusion: We detected that myocardial perfusion is preserved in the patients with AS. However, left ventricular wall motion abnormalities are seen. We concluded that ankylosing spondylitis may be associated with microvascular dysfunction and gated myocardial perfusion scintigraphy could be valuable in AS patients for the evaluation of LV function even if the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score are low and the disease duration shorter. (C) 2010 Elsevier Espana, S.L. and SEMNIM. All rights reserved.Öğe Myocardial perfusion is preserved in patients with psoriasis without clinically evident cardiovascular disease(Wiley, 2009) Yalcin, H.; Balci, D. D.; Ucar, E.; Ozcelik, N.; Tasci, C.; Seyfeli, E.; Akgul, F.Psoriasis is associated with a premature atherosclerosis due to the chronic inflammatory process. To evaluate the effect of disease process on myocardial perfusion, we planned to perform 99mTc-MIBI myocardial perfusion single photon emission computed tomography (SPECT) in patients with psoriasis. The study group consisted of 28 psoriasis patients (17 men, 11 women), aged 18-76 years, and mean age 41.2 +/- 14.1 years. The patients were selected among those who were older than 18 years and longer than 10 years of disease duration with more than two times of systemic treatment. All patients underwent 99mTc-MIBI myocardial perfusion SPECT with the same day protocol. We detected various risk factors including smoking habits in 7, family history of cardiovascular disease in 4, hypertension in 1, hyperlipidemia in 9 patients. We completed myocardial perfusion SPECT for each patient and found normal perfusion pattern in SPECT images. We detected that myocardial perfusion is preserved in the patients with psoriasis. The majority of acute heart attacks are caused by noncritical coronary stenosis and this may be an explanation for increased cardiovascular risk in these patients despite normal coronary perfusion.
