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    Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department
    (Scientific Publishers of India, 2016) Yaman, Fatih Nazmi; Civelek, Birol; Yavuz, Bunyamin; Yilmaz, Mustafa; Atescelik, Metin; Sahan, Mustafa; Goktekin, Mehmet Cagri
    Objective: To evaluate the relationship between CHA2DS2-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA2DS2- VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA2DS2-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA2DS2-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA2DS2-VASc score being ? 2. The mean age of patients was 68 ± 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA2DS2-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA2DS2-VASc and these markers in high-risk patients with CHA2DS2-VASc score ? 2. © 2016, Scientific Publishers of India. All rights reserved.
  • Küçük Resim
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    Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department.
    (Allied Acad, 2016) Yaman, Fatih Nazmi; Civelek, Birol; Yavuz, Bunyamin; Yilmaz, Mustafa; Atescelik, Metin; Sahan, Mustafa; Goktekin, Mehmet Cagri
    Objective: To evaluate the relationship between CHA(2)DS(2)-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA(2)DS(2)-VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA(2)DS(2)-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA(2)DS(2)-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA(2)DS(2)-VASc score being >= 2. The mean age of patients was 68 +/- 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA(2)DS(2)-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA(2)DS(2)-VASc and these markers in high-risk patients with CHA(2)DS(2)-VASc score >= 2.
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    Öğe
    One-Sided Weakness Admitted with Hypokalemic Periodic Paralysis
    (Derman Medical Publ, 2014) Yaman, Fatih Nazmi; Sahan, Mustafa; Yilmaz, Mustafa
    Hypokalemic periodic paralysis (HPP) is a genetic disorder that characterized by recurrent attacks of skeletal muscle weakness with associated hypokalemia which is precipitated by hypotermia, stress, infection, carbonhydrate load, glucose infusion, metabolic alkalosis, general anesthesia, steroids and licorice root. 52-year-old male patient while working in a cold enviroment, began to complain of weakness in the arms and legs. The patient was brought to the emergency department due to the continuation of weakness complaints in the left arm and leg. The neurological examination had 5/5 strength in the upper-right and lowerright extremities, 3/5 strength in the upper-left and lower-left extremities. Serum electrolytes: Potassium: 2.7 mEq/L, 1.9 mEq/L control. There was no evidence of bleeding and infarction in Computerized Brain Tomography and Brain MR. After intravenous infusion of potassium, at the third hour the patient's neurological symptoms resolved completely, patient was mobilized. In this case we present one-sided weakness admitted to the emergency department, the diagnosis of patient with HPP. We aimed to emphasize that this diagnosis should be keeping in mind that among the causes paralysis and delayed diagnose and treatment may be mortal in HPP.