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Öğe Cases of incidental papillary carcinoma in thyroidectomy materials in the elderly(Acta Medica Mediterranea, 2014) Yanik, Serdar; Karaca, Turgut; Akkoca, Ayşe Neslin; Özdemir, Zeynep Tuğba; Kaynar, Ayşegül; Çinçin, Tarik Gandi; Yanik, Semra VatanObjective: Papillary microcarcinomas constitute more than half of thyroid cancers and incidentally detected between 2.7% and 36% ratios in all age groups in autopsy studies. Our aim in this study was to evaluate the incidental papillary thyroid carcinoma in surgical materials sent to the pathology department of 60 years and older patients. Materials and methods: In this study, 307 thyroid surgery materials were screened from the archive of the Department of Pathology in Iskenderun State Hospital between January 2012 and November 2013. 27 thyroid specimens of patients over 60 years and older with definite diagnosis were evaluated. Results: Between the ages of 60 to 84 the mean age of the patients was 65.70 ± 5.60. 19 (70.37%) of the patients were females, 8 (29.63%) of the patients were males. Histopathological examination of the subjects revealed nodular goiter in 16 (59.26%) cases, lymphocytic thyroiditis in 3 (11.11%) cases, granulomatous thyroiditis in one (3.70%) case, thyroid tumors in 6 (22.22%) cases. In this age group no benign tumors ( adenomas ) have been detected and all of the six tumors (22.22%) were malignant. Type of cancer were detected as oncocytic carcinoma in one(3.70%) case and papillary carcinoma in 5 (19.52%) cases. Conclusion: In our study we detected that 22.22 % of thyroid pathologies of over 60 years old patients were malignant . In this study, although the number of cases is small, we reached a remarkable conclusion in terms of the frequency of malignant thyroid pathologies in the elderly. Further prospective studies with a greater number of patients will be beneficial.Öğe CASES OF INCIDENTAL PAPILLARY CARCINOMA IN THYROIDECTOMY MATERIALS IN THE ELDERLY(Carbone Editore, 2014) Yanik, Serdar; Karaca, Turgut; Akkoca, Ayse Neslin; Ozdemir, Zeynep Tugba; Kaynar, Aysegul; Cincin, Tarik Gandi; Yanik, Semra VatanObjective: Papillary microcarcinomas constitute more than half of thyroid cancers and incidentally detected between 2.7% and 36% ratios in all age groups in autopsy studies. Our aim in this study was to evaluate the incidental papillary thyroid carcinoma in surgical materials sent to the pathology department of 60 years and older patients. Materials and methods: In this study, 307 thyroid surgery materials were screened from the archive of the Department of Pathology in Iskenderun State Hospital between January 2012 and November 2013. 27 thyroid specimens of patients over 60 years and older with definite diagnosis were evaluated. Results: Between the ages of 60 to 84 the mean age of the patients was 65.70 +/- 5.60. 19 (70.37%) of the patients were females, 8 (29.63%) of the patients were males. Histopathological examination of the subjects revealed nodular goiter in 16 (59.26%) cases, lymphocytic thyroiditis in 3 (11.11%) cases, granulomatous thyroiditis in one (3.70%) case, thyroid tumors in 6 (22.22%) cases. In this age group no benign tumors ( adenomas ) have been detected and all of the six tumors (22.22%) were malignant. Type of cancer were detected as oncocytic carcinoma in one(3.70%) case and papillary carcinoma in 5 (19.52%) cases. Conclusion: In our study we detected that 22.22 % of thyroid pathologies of over 60 years old patients were malignant . In this study, although the number of cases is small, we reached a remarkable conclusion in terms of the frequency of malignant thyroid pathologies in the elderly. Further prospective studies with a greater number of patients will be beneficial.Öğe TNM and Modified Dukes staging along with the demographic characteristics of patients with colorectal carcinoma(E-Century Publishing Corp, 2014) Akkoca, Ayse Neslin; Yanik, Serdar; Ozdemir, Zeynep Tugba; Cihan, Fatma Goksin; Sayar, Suleyman; Cincin, Tarik Gandi; Cam, AkinAim: Colon adenocarcinoma, is the most common cancer in gastrointesinal system (GIS). The whole world is an important cause of morbidity and mortality. TNM and modified Dukes classification which has great importance in the diagnosis and treatment of Colorectal cancer (CRC). TNM and Modified Dukes classification results of histopathological examination and the demographic characteristics of patients and their relation were investigated. Materials and methods: Lower gastrointestinal operation results of 85 patients were examined accepted to clinical Pathology between January 1997-November 2013. Colon cancer had been diagnosed at 85 patients with pathology materials and staging was done according to the TNM and Modified Duke classification. The demographic characteristics of patients, differentiation grade, lymph node involvement, serous involvement were evaluated retrospectively. Results: In this study 37 patients (43.52%) were men and 48 (56.47%) were women. Ages of patients were between 19 and 87 with a mean age of 57.31 +/- 15.31. Lymph node, differentiation, serosa involvement, Modified Dukes and TNM classification was assessed according to sex and age. TNM classification by sex was not statistically significant (p > 0.05). There was no statistically significant relationship between age and differentiation (p = 0.085). Value of differentiation increased towards from 1 to 3 inversely proportional to age. So young patients defined as well-differentiated at the conclusion. Negative relationship was evaluated between age and TNM Class variables. As a result, the relationship between age and TNM was not significant (p > 0.05). However, with increasing age the degree of staging was also found to increase. TNM classification was associated with the differentiation and it was significant (p = 0.043). Conclusion: Colon cancer, when contracted at an early stage, it is suitable for surgery and curative treatment can be done with minimal morbidity and mortality. However, some of the patients have advanced disease at diagnosis and their 5-year survival rate is only 8%. Every year there is prolongation of overall survival of colon cancer. It is so common cancer type so that determination of prognostic factors, disease staging and treatment strategy which affects survival is significant.
