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Öğe Accumulation of nonessential potentially toxic trace elements (PTEs) in the some economically important seafood species of Mediterranean(2014) Yarsan, Ender; Yipel, Mustafa; Altınok Yipel , Fulya; Dikmen, BilalBu çalışma Akdeniz Antalya Körfezi’nde avlanan ekonomik öneme sahip bazı deniz ürünleri türlerindeki (Mullus barbatus, Linnaeus, 1758, Mugil cephalus, Linnaeus, 1758, Panaeus semisulcatus, De Haan, 1844) bazı esansiyel olmayan potansiyel toksik iz elementlerin (PTEs) birikim düzeylerinin ICP-OES (İndüktif Eşleşmiş Plazma-Optik Emisyon Spektrometresi) kullanılarak belirlenmesi için yapılmıştır. Örneklere ait belirlenen sonuçların ortalama ve standart sapmaları Barbunya (M. barbatus) için Ag (0.030±0.017 mg/kg), Al (12.163±7.298 mg/kg), As (0.269±0.121 mg/kg), Ni (0.084±0.067 mg/kg), Sn (0.022±0.003 mg/kg) olarak; Kefal (M. cephalus) için Ag (0.038±0.024 mg/kg), Al (11.120±4.019 mg/kg), As (0.140±0.082 mg/kg), Ni (0.060±0.050 mg/kg), Sn (0.022±0.003 mg/kg) olarak ve Yeşil Kaplan Karidesi (P. semisulcatus) için Ag (0.032±0.029 mg/kg), Al (20.924±9.829 mg/kg), As (0.249±0.116 mg/kg), Ni (0.124±0.102 mg/kg), Sn (0.026±0.004 mg/kg) olarak belirlenmiştir. İz elemetlerin belirlenen düzeyleri Al dışındakilerde ulaşılabilen günlük alım limitlerinin altında kalmıştır. Ayrıca Antalya Körfezi’nde yapılmış diğer çalışmalar değerlendirildiğinde Al düzeyleri yüksektir. Bu sonuçlar çevre kirliliği konusundaki yasal yaptırımların artmasına rağmen körfezden avlanan deniz ürünlerinin Al’a yüksek oranda mağruz kaldığını göstermiştir.Öğe Accumulation of Nonessential Potentially Toxic Trace Elements (PTEs) in the Some Economically Important Seafood Species of Mediterranean(Kafkas Univ, Veteriner Fakultesi Dergisi, 2014) Yarsan, Ender; Yipel, Mustafa; Altinok Yipel, Fulya; Dikmen, BilalThis study was conducted to determine the levels of some nonessential potentially toxic trace elements (PTEs) (Ag, Al, As, Ni, Sn) of some economically important seafood species (Mullus barbatus, Linnaeus, 1758, Mugil cephalus, Linnaeus, 1758, Panaeus semisulcatus, De Haan, 1844) caught in the Gulf of Antalya Mediterranean Sea by using ICP-OES (Inductively Coupled Plasma-Optic Emission Spectrophotometer). The averages and the standard deviations of the results of the samples were determined as Ag (0.030 +/- 0.017 mg/kg), Al (12.163 +/- 7.298 mg/kg), As (0.269 +/- 0.121 mg/kg), Ni (0.084 +/- 0.067 mg/kg), Sn (0.022 +/- 0.003 mg/kg) for the Red Mullet (M. barbatus), Ag (0.038 +/- 0.024 mg/kg), Al (11.120 +/- 4.019 mg/kg), As (0.140 +/- 0.082 mg/kg), Ni (0.060 +/- 0.050 mg/kg), Sn (0.022 +/- 0.003 mg/kg) for the Grey Mullet (M. cephalus), Ag (0.032 +/- 0.029 mg/kg), Al (20.924 +/- 9.829 mg/kg), As (0.249 +/- 0.116 mg/kg), Ni (0.124 +/- 0.102 mg/kg), Sn (0.026 +/- 0.004 mg/kg) for the Green Tiger Prawn (P. semisulcatus). The determined levels of trace elements were below the available daily intake limits except Al. Also evaluation of other studies conducted in the Gulf of Antalya, Al levels are higher. These results showed that, although increasing the legal rules about environmental pollution, seafood species which caught from the Gulf are exposed to Al in a higher rate.Öğe Concentrations of Essential and Non-essential Toxic Trace Elements in Wild Boar (Sus Scrofa L., 1758) Tissues from Southern Turkey(Springer, 2014) Yarsan, Ender; Yipel, Mustafa; Dikmen, Bilal; Altintas, Levent; Ekici, Husamettin; Koksal, AliWild animals, including wild boars, are suitable for use as bioindicators. The aim of this study was to evaluate the concentrations of selected essential (Co, Cu, Fe, Se, Zn) and non-essential (As, Cd, Pb) potentially toxic trace elements in various tissues (hair and hoof) of wild boars hunted in the vicinity of Antalya province in Turkey, in relation to hunting seasons. Concentrations in mg/kg on dry weight basis were determined as 0.37 +/- A 0.27 mg/kg for As, 0.05 +/- A 0.04 mg/kg for Cd, 0.24 +/- A 0.33 mg/kg for Co, 4.84 +/- A 2.48 mg/kg for Cu, 289.94 +/- A 165.26 mg/kg for Fe, 8.71 +/- A 15.68 mg/kg for Pb, 0.24 +/- A 0.10 mg/kg for Se, and 28.99 +/- A 21.41 mg/kg for Zn in the hair samples; and as 0.11 +/- A 0.04 mg/kg for As, 0.01 +/- A 0.04 mg/kg for Cd, 0.01 +/- A 0.01 mg/kg for Co, 1.03 +/- A 0.25 mg/kg for Cu, 56.88 +/- A 18.68 mg/kg for Fe, 0.30 +/- A 0.18 mg/kg for Pb, 0.11 +/- A 0.05 mg/kg for Se, and 17.91 +/- A 10.98 mg/kg for Zn in the hoof samples.Öğe Distribution and Ecotoxicological Risk Assessment of Heavy Metals in Streams of Amanos Mountains from Southern Turkey(Springer, 2021) Yipel, Mustafa; Tekeli, Ibrahim Ozan; Dikmen, Bilal; Yarsan, EnderAssessing the potential ecological risks of chemical pollutants like heavy metals is a key tool of a sustainable environment. With this goal, ecotoxicological significant metal (Al, As, Cd, Cr, Cu, Fe, Hg, Ni, Pb, and Zn) levels of the water (n = 32) and sediment (n = 32) samples of streams [rural (8 points) and urban (8 points) sides] on Amanos Mountains were determined by inductively coupled plasma-optical emission spectrometry (ICP-OES) and ecotoxicological risk assessment was performed through the potential ecological risk index (RI). The study region with intense urban activities has also ecological importance with regards to wildlife. It is located on the migration route of birds, hosts loggerhead and green sea turtles, Mediterranean seals, and some terrestrial species like mountain gazelle and striped hyena. All calculated RI values were below the potential risk limits and the ecotoxicological risk was observed to be very low. Metal levels should be monitored periodically, and necessary measures should be taken before the reflection of the increase to be determined by the risk assessment on the ecosystem.Öğe Effect of induction agents on the antioxidative activity of desflurane in dogs(2008) Altuğ, Muhammed Enes; Gönenci, Ramazan; Yarsan, Ender; Öztürk, AtakanThe objective of this study was to determine the effects of different induction agents on the antioxidative activity of desflurane in dogs. Sixteen healthy male crossbreed dogs, aged between 1 and 2 years and weighing between 16 and 22 kg were equally divided into two groups. Anaesthetic protocols were designed as midazolam + thiopental + desflurane (Thio-Des group) or midazolam + ketamine + desflurane (Ket-Des group). Anaesthesia was induced with 0.3 mg kg-1 midazolam + 10 mg kg-1 thiopental or 0.3 mg kg-1 midazolam + 10 mg kg-1 ketamine hydrochloride combinations intraveneously. Anaesthesia maintenance was continued for 70 min(s) with 7-8% desflurane. Blood catalase, superoxide dismutase and hemoglobin activities were measured at control, anaesthesia induction, during the desflurane anaesthesia, one hour after anaesthesia and 24 hours after anaesthesia. In conclusion, thiopental administration in the anaesthesia induction increased superoxide dismutase activity (p<0.05), whereas ketamine administration increased the catalase (p<0.05) and hemoglobin (p<0.01) activities during desflurane anaesthesia. But, these enzymes simultaneously decreased in both groups one day after anaesthesia (p>0.05). Therefore, it is possible that induction agents play a significant rol on the antioxidative effects of desflurane anaesthesia.Öğe A Risk Assessment of Heavy Metal Concentrations in Fish and an Invertebrate from the Gulf of Antalya(Springer, 2014) Yipel, Mustafa; Yarsan, EnderThis study was conducted to determine the levels of Cd, Cu, Zn and Pb in the Red mullet (Mullus barbatus), Grey mullet (Mugil cephalus) and Green tiger prawn (Panaeus semisulcatus) species caught in the Gulf of Antalya and to assess the health risks associated with their consumption. The average values (mg/kg d.w.) were calculated to be Pb (0.29 +/- A 0.14), Cd (0.02 +/- A 0.03), Zn (5.64 +/- A 1.58) and Cu (1.64 +/- A 1.02) in M. barbatus; Pb (0.22 +/- A 0.12), Cd (0.02 +/- A 0.01), Zn (7.66 +/- A 2.29) and Cu (1.33 +/- A 0.82) in M. cephalus; Pb (0.25 +/- A 0.16), Cd (0.04 +/- A 0.05), Zn (13.33 +/- A 3.34) and Cu (5.15 +/- A 2.09) in P. semisulcatus. The detected levels of the studied metals were below the legal and daily intake limits according to national and international standards, although the mean Pb level in M. barbatus was close to the legal limit (0.30 mg/kg). Target hazard quotient values were also all below 1, meaning that there is no health risk.Öğe Spectrophotometric determination and stability studies of sulfamethoxazole and trimethoprim in oral suspension by classical least square calibration method(Hacettepe University, Faculty of Pharmacy, 2009) Hişmio?ullari, Şahver Ege; Yarsan, EnderQuantitative determination and stability test of sulfamethoxazole and trimethoprim in oral suspension were carried out by spectrophometric classical least square calibration method. Stability test of the related veterinary drugs was performed by using the following conditions: Room temperature, refrigerator and etuve (37 0C) for each 3 month during 12 months. For the spectrophotometric analysis, the standard series of sulfamethoxazole and trimethoprim was prepared in the concentration range of 2.0-11.0 ?g/mL and 3.0-18.0 ?g/mL respectively. The absorbances of standard series were measured at three-wavelength set (237, 257 and 288 nm). A classical least square calibration was obtained by using the absorptivities at three-wavelength set. The validity of the spectral method was done by analyzing the synthetic binary mixtures. Afterwards the method was successfully applied to simultaneous analysis and stability test of the commercial veterinary formulation containing sulfamethoxazole and trimethoprim.
