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A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening
(Springer Heidelberg, 2011) Silfeler, Dilek B.; Tandogan, Bulent; Ayvaci, Habibe; Silfeler, Ibrahim; Yenidede, Ilter; Dayicioglu, Vedat
We compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming. A total of 218 patients were enrolled to receive between one and three treatments according to physicians' options. The end points were: (1) vaginal delivery or Bishop score a parts per thousand yen8 at the end of 12 h, (2) vaginal delivery by 12 h or difference a parts per thousand yen4 between the initial and 12th hour Bishop scores. Statistical analyses were performed with ANOVA, Krustal Wallis, Scheffe, chi A(2), Fisher, Advanced chi A(2), and Kolmogorov-Smirnov tests. Tukey's HSD was used as a post hoc test. Misoprostol showed statistical significance for the rate of vaginal delivery < 12 h, a parts per thousand yen8 Bishop score at the end of 12 h, and cervical change of a parts per thousand yen4 Bishop scores within 12 h (p = 0.013). Comparison between cases Bishop score < 4 showed that misoprostol is more effective than dinoprostone and oxytocin. Considering Bishop score = 0 cases we calculated no statistical significance.