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    Effects of surgical and percutaneous tracheotomy on thyroid hormones
    (Edizioni Luigi Pozzi, 2019) Yetim, Tulin Durgun; Ozer, Gul Soylu; Karaaslan, Kerem; Yetim, Brahim; Kilic, Erol
    Aim: To evaluate the effects of surgical and percutaneous tracheotomy on thyroid hormones. MATERIAL AND METHOD: Sixty patients with respiratory problems who underwent surgical tracheotomy and percutaneous tracheotomy between December 2012 and December 2016 were divided into 2 groups. FT3, FT4, thyroglobulin and TSH levels of the groups were statistically evaluated preoperatively and postoperatively. RESULTS: The effects of surgical and percutaneous tracheotomy on free thyroxin (FT4), serum thyroglobulin (TG) and thyroid stimulating hormone (TSH) levels were found to be statistically significant. Although free triiodothyronine (FT3) slightly elevated in both groups, it was not statistically significant. DISCUSSION: Today, percutaneous tracheotomy (PCT) and conventional surgical tracheotomy (CT) have been widely used in intensive care units on patients who are expected to be connected to mechanical ventilation for a long time. Because of the anatomy of the surgical site, tracheotomy may cause damage to the adjacent thyroid gland and tracheal rings CONCLUSION: Surgeons should keep in mind that serum thyroid hormone levels may increase postoperatively. Particularly the patients with cardiac rhythm problems should be followed after surgical and percutaneous tracheotomy due to the systemic effects of thyroid hormones.
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    The role of combination pre- and postoperative albendazole therapy in the surgical management of liver hydatidosis
    (Edizioni Luigi Pozzi, 2018) Yetim, Brahim; Kilic, Erol
    AIMS: ALB is the most commonly used drug for the treatment of echinococcosis. The aim of the present study was to evaluate the effect of ALB using the intraoperative and perioperative periods as dual therapy. MATERIALS AND METHODS: Material of this retrospective study were the consecutive series of 98 patients operated for hepatic hydatidosis (HC) over a period of 7 years, at a single centre. Clinical examination, ultrasonography (US) and computed tomography (CT) were used for establishing diagnosis. Ninety-eight cases of hepatic hydatidosis were treated by albendazole intraoperatively and postoperatively together with surgery. Perioperative ALB treatment was given in a dose of 12-15 mg/ kg per day in four divided doses. The treatment started 2-28 days before the surgery when the diagnosis was established and continued for 2-24 months postoperatively in a cyclic monthly form. A total of 1.7 mg/mL ALB solution was used intraoperatively. Dual albendazole treatment (DALB) includes preoperative and postoperative oral ALB treatment and intraoperative irrigation of cystic cavity with ALB. RESULTS: In the follow-up period one patient died and there was one recurrence of hepatic hydatidosis.Morbidity rates were 10.89% . CONCLUSION: Results of this study suggest that ALB treatment with HC surgery is effective in the prevention of recurrences and/or secondary hydatidosis.