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Öğe The effect of personal, familial, and environmental characteristics on acne vulgaris: a prospective, multicenter, case controlled study(Edizioni Minerva Medica, 2019) Karadag, Ayse S.; Balta, Ilknur; Saricaoglu, Hayriye; Kilic, Selim; Kelekci, Kiymet H.; Yildirim, Mehmet; Arica, Deniz A.BACKGROUND: There are only a few studies about epidemiological features of acne vulgaris in the literature. The aim of this study was to analyze demographic, clinical, familial and environmental characteristics of acne, the role of diet and aggravating factors and association of these factors with acne severity. METHODS: Patients with a diagnosis of mild-moderate to severe acne were consecutively interviewed at the participating centers during the study period. RESULTS: A total of 3826 patients and 759 control patients were involved in this study. Mild acne was the most common type of acne, and most of the lesions were localized on face followed by the trunk. The severity of acne was worse in patients who had a positive family history of acne. The most common triggering factor was psychological stress. We found a positive correlation with chocolate, bread, green tea, milk, white sugar, ripe banana, ice cream, apple, orange, and red meat consumption. As we compare the acne severity according to geographical features we detected mild-moderate acne was more common in Mediterranean region and severe acne was more common in East Anatolian region. Family history positivity was more common in Aegean region and least common in Central Anatolian region. There was statistically significant relationship as we compare acne severity and dietary factors such as chocolate, dairy products such as milk, sunflower seed consumption within the geographical regions. CONCLUSIONS: This study presents the demographic and clinical characteristics of acne patients in Asian and the European parts of Turkey. We believe that this study will provide a useful overview of acne in Turkey.Öğe Evaluation of self-esteem and dermatological quality of life in adolescents with atopic dermatitis(Deri Zuhrevi Hastaliklar Dernegi, 2013) Erturan, Ijlal; Aktepe, Evrim; Balci, Didem Didar; Yildirim, Mehmet; Sonmez, Yonca; Ceyhan, Ali MuratBackground and Design: Atopic dermatitis is a chronic, inflammatory skin disease characterized by itchy skin lesions. Since adolescents are intensely interested in their physical appearance, chronic skin diseases in this period can adversely affect the development of self esteem. Atopic dermatitis is a skin disease that affects the appearance and there is an heightened attention to the body image in adolescence which is an important period of time in the development of self-esteem. Therefore, we aimed to investigate self-esteem and dermatological quality of life in adolescents with atopic dermatitis. Materials and Methods: Thirty-three patients with atopic dermatitis and 33 healthy controls were included in the study. The Piers-Harris Children's Self-Concept Scale and the Children's Dermatology Life Quality Index (CDLQI) were used for determining self-esteem and quality of life. The Scoring of Atopic Dermatitis (SCORAD) Index was used to assess the severity of atopic dermatitis. Results: It was found that patient group had lower self-esteem than healthy controls according to the Piers-Harris Children's Self-Concept Scale. A statistically significant difference was observed in happiness/satisfaction and anxiety subscale scores between the patients and healthy controls while there was no significant difference between the other sub-scale scores. Mean value of dermatological quality of life in patients with atopic dermatitis was significantly lower than in healthy controls. A moderate negative correlation was found between self-esteem and CDLQI scores among adolescents with atopic dermatitis. Discussion: This study results have shown that self-esteem and dermatological quality of life were adversely affected in adolescents with atopic dermatitis irrespective of gender. These patients should be examined psychiatrically besides dermatological examination and treatment. We suggest that improvement will be observed in self-esteem and quaky of life of adolescents with atopic dermatitis by providing the necessary psychosocial support.Öğe The evaluation of SIRS status with hemato-biochemical indices in bitches affected from pyometra and the Usefulness of these indices as a potential diagnostic tool(Elsevier Science Inc, 2022) Yazlik, Murat Onur; Mutluer, Ipek; Yildirim, Mehmet; Kaya, Ufuk; Colakoglu, Hatice Esra; Vural, Mehmet RifatThe aims of this study were to establish a cut-off point by evaluating the usability of the hemato-biochemical indices to determine the severity of inflammation caused by pyometra, and to determine the practical usage of the indices as a diagnostic biomarker in cases of pyometra. Animals that were admitted to Ankara University Veterinary Faculty Obstetrics and Gynecology Clinic were included in the present study. Dogs suffering from pyometra were allocated to two groups according to their SIRS status (SIRS, n = 12; Non-SIRS (NSIRS, n = 16)). Healthy dogs presented for routine ovariohysterectomy were used as the control (n = 13). Blood samples were collected into two tubes containing EDTA for hema-tological analysis and without anticoagulant for biochemical tests before the beginning of treatment. Hemato-biochemical indices, which are Neutrophil-Lymphocyte Ratio (NLR), Monocyte-Lymphocyte Ratio (MLR), Neutrophil Percentage-Albumin Ratio (NPAR), Platelet-Lymphocyte Ratio and Systemic Immune-Inflammation Index, were calculated. All data were analyzed using the MIXED procedure of the SPSS. Receiver operating characteristics curves were used to determine the dog level threshold for evaluating the SIRS status and used to determine a predicted threshold with hemato-biochemical indices for differentiation between dogs with pyometra (regardless of SIRS status) and the control. Pairwise comparisons were carried out of the area under the curve (AUC) for thresholds of SII, NLR, PLR, MLR, NPAR. White blood cells, lymphocytes, monocyte, neutrophil, ALP, NLR, MLR, and NPAR levels were greater in dogs that suffer from SIRS (P < 0.05). Red blood cells and hematocrit levels were significantly higher in the control group (P < 0.05). Albumin levels were higher in the control group (P < 0.05). Moreover, NLR, MLR and NPAR levels were found to be significantly higher in the SIRS group (P < 0.05). Besides, NLR and MLR were the best predictors for diagnosis of the SIRS with the AUC values of 0.936, and 0.966 respectively. Furthermore, NLR, MLR and SII could be a useful diagnostic tool for pyometra with the AUC values of 0.955, 0.931, 0.716. The blood indices could be used as fast, easily accessible, and inexpensive markers for the evaluation of the SIRS status in dogs with pyometra together with diagnosis.(c) 2022 Elsevier Inc. All rights reserved.Öğe Macronutrient concentration and remobilization in spring wheat organs during grain filling(Tubitak Scientific & Technological Research Council Turkey, 2014) Tiryakioglu, Murat; Yildirim, Mehmet; Karanlik, SemaThis study was conducted with 4 bread wheat genotypes to determine the macronutrient content in different plant organs during the grain filling period. Macronutrient contents such as nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), and magnesium (Mg) were determined in lower stems, peduncles, lower leaves, flag leaves, rachises, florets, and grains. High genotype effects were found for all macronutrients and plant organs. N, P, K, and Mg decreased during grain filling in all plant parts except the grain. The rate of decrease varied depending on plant organs and nutrients. Grain nutrient concentration, except nitrogen content, increased up to physiological maturity. In contrast to the other nutrients, Ca content increased or remained stable depending on the plant organs. The macronutrient remobilization order from plant organs to grain was Mg < P < N < K <= Ca, and all nutrients were accepted as removable at grain development stages. Remobilization models of macronutrients in grains can be valuable for detecting high-capacity plants for nutrient accumulation in stressful environments. Relationships among macronutrients and their relationships with plant organs can be used, by way of indirect selection, in wheat breeding efforts.Öğe Micronutrients (Fe, Mn and Zn) concentration and remobilization in spring wheat organs during grain filling(Gaurav Publications, 2013) Tiryakioglu, Murat; Yildirim, Mehmet; Karanlik, Sema; Ergun, NurayThe trials were conducted during 2008-09 and 2009-10 wheat growing seasons. Four wheat genotypes (Triticum aestivum L.) were grown in field conditions to study Fe, Mn and Zn content in different plant organs during the grain-filling period. Micronutrient contents of plant organs including lower stems, peduncle, lower leaves, flag leaf, rachis, florets and grain were measured at four stages between anthesis and physiological maturity. Analysis of variance showed high genotype and measurement stage effects for all plant organs. Fe contents in stems declined during grain filling, whereas it increased for rachis, florets and grain, and remained constant in leaves. Mn content of plant parts stayed generally constant until grain maturity, except in stems. Zn sharply decreased during grain filling for all plant parts, except grain. The micronutrients remobilization order from plant organs to grain was Zn
