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Öğe Effects of habitual knuckle cracking on metacarpal cartilage thickness and grip strength(Elsevier, 2017) Yildizgoren, M. T.; Ekiz, T.; Nizamogullari, S.; Turhanoglu, A. D.; Guler, H.; Ustun, N.; Kara, M.Joint cracking involves a manipulation of the finger joints resulting in an audible crack. This study aimed to determine whether habitual knuckle cracking (KC) leads to an alteration in grip strength and metacarpal head (MH) cartilage thickness. Thirty-five habitual knuckle crackers (cracking their joints >= 5 times/day) (20 M, 15 F, aged 19-27 years) and 35 age-, gender-, and body mass index-matched non-crackers were enrolled in the study. MH cartilage thickness was measured with ultrasound and grip strength was measured with an analog Jamar hand dynamometer. Grip strength was similar between groups (P > 0.05). Habitual knuckle crackers had thicker MH cartilage in the dominant and non-dominant hands than those of the controls (P = 0.038 and P = 0.005, respectively). There was no correlation between MH cartilage thickness and grip strength in both groups (P > 0.05). While habitual KC does not affect handgrip strength, it appears to be associated with increased MH cartilage thickness. (C) 2016 SFCM. Published by Elsevier Masson SAS. All rights reserved.Öğe The Relationship between Serum IL-17 and IL-23 Levels, and Other Disease Activity Parameters in Patients with Behcet's Disease(Univ West Indies Faculty Medical Sciences, 2023) Kucuksahin, O.; Sahin, A.; Yildizgoren, M. T.; Turgay, M.; Kinikli, G.Objective: To investigate the relationship between disease activity and the involvement of Behcet's disease (BD) and serum levels of interleukin (IL)-17 and IL-23. Methods: Sixty patients with BD and 20 healthy control group subjects were included in this study. The patients were divided into four groups according to clinical findings as follows: entero-Behcet, mucocutaneous-Behcet, neuro-Behcet and vascular-Behcet. The serum levels of the IL-17 and IL-23 levels were evaluated using enzyme-linked immunosorbent assay. Results: Of the BD patients, 15 (25%) had active disease and 45 (75%) had inactive disease. The serum levels of IL-23 and IL-17 were statistically significantly higher in the patients with BD than in the control groups (p < 0.05). A significant relationship was also observed between the disease activity, and both the erythrocyte sedimentation rate and the C-reactive protein levels (p < 0.05). The mean serum levels of IL-17 and IL-23 in patients with active disease were 0.07 0.25 pg/ml and 36.0 30.5 pg/ml, respectively. There was no statistically significant relationship between the disease activity and the serum levels of IL-17 and IL-23 (p > 0.05). There were also statistically significant relationships between the disease activity and uveitis, retinal vasculitis or superficial thrombophlebitis. Conclusion: No relationship was found between BD and serum levels of the IL-17 and the IL-23.