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Öğe Calcified chronic subdural hematoma(2012) Aras, Mustafa; Altaş, Murat; Yilmaz, Atilla; Serarslan, Yurdal; Urfali, Boran; Yilmaz, NebiCalcified subdural hematoma is a rarely seen event. It may develop secondary to previous trauma or inappropriate surgical procedures. Due to the not well understood etiology, there are variations in the treatment choices. We present a 27-year old male patient with calcified chronic subdural hematoma. He was operated on following an motorcycle accident in another hospital 5 years ago. He was admitted to our hospital complaining about seizure, headache and dizziness. Neuroradiological examination revealed a calcified chronic subdural hematoma was detected on the right hemisphere. The patient was hospitalized and put on anti-epileptic and analgesic drugs. Any surgical treatment was not applied. In cases with calcified chronic subdural hematoma, the decision of surgical operation should be decided after a carefully and meticulously investigation. It should be avoided any profitless and likely harmful surgical procedures. The clinical observation may be appropriate in the determination of treatment approaches. © 2012 OMU.Öğe Cavernous Hemangioma Presenting as a Giant Cervical Mass: A Case Report(Turkish Neurosurgical Soc, 2010) Kiymaz, Nejmi; Yilmaz, Nebi; Ozen, Suleyman; Demir, Ismail; Gudu, Burhan Oral; Kozan, AbdulbakiIntramuscular hemangiomas of the head and, neck are rare congenital vascular tumors and are sparsely reported. Hemangiomas account for approximately 7% of benign tumors and usually present as a mass that suddenly enlarges. Hemangiomas are mostly seen on the trunk and extremities, but can also appear on the head and neck region. A 10-year-old boy was referred to our clinic for puffiness and swelling on the right side of his neck. Neurological examination was normal, but we observed an advanced degree of restriction in neck movement. An MRI study showed a soft tissue mass 9x8x5 in size. The mass was totally extracted by surgical intervention and pathological analysis revealed that it was a cavernous hemangioma. The patient's neck movement returned to normal after surgery. No relapse occurred during 1-year follow-up.Öğe Does pregnancy induce or enhances low back pain?(2006) Kiymaz, Nejmi; Yilmaz, Nebi; Zetero?lu, Şahin; Yazici, TanerForty-eight pregnant women out of 166 referred to our obstetrics and gynecology outpatient clinic due to back pain between February and March 2003 were included in the present study. A questionnaire booklet was prepared for age, weight gain during pregnancy, number of parities, existence of any back pain in their former pregnancies, the start of back pain during pregnancy, physical work conditions and route of previous labour information. These patients were followed for a period of 1.5 years after labour. The factors that influenced back pain in the pregnant patients were: multiparity, former back pain during pregnancy, and weight gain during pregnancy. We determined lumbar discopathy at a ratio of 79.1% using MRI (Magnetic Resonance Imaging) study of the lumbar vertebrae in patients with back pain lasting more than a one year. © 2006 VSP.Öğe The Dowling-Orlando technique in a giant primary cerebral hydatid cyst: a case report(Via Medica, 2010) Altas, Murat; Serarslan, Yurdal; Davran, Ramazan; Evirgen, Omer; Aras, Mustafa; Yilmaz, NebiHydatid cyst disease is a parasitic illness that is rarely located in the brain. We present a case of a 26-year-old female who complained of headache, nausea, and vomiting. The diagnosis was intracranial hydatid cyst disease and was confirmed with radiological and serological tests. Neurological examination revealed papilloedema and left-sided pyramidal signs. She was operated on using the Dowling-Orlando technique. The cyst was removed without rupture, and therapy was completed with albendazole for a period of four weeks. In this article, we discuss the application of the Dowling-Orlando technique, microsurgery, the Valsalva manoeuvre and the positioning of the patient such that gravity could facilitate surgical removal of a giant cerebral hydatid cyst.Öğe Electrophysiological and Clinical Assessment of Response to Surgery in Carpal Tunnel(Informa Healthcare, 2010) Yilmaz, Nebi; Akdemir, Gokhan; Gezici, Ali Riza; Basmaci, Mehmet; Ergungor, Mehmet Fikret; Asalanturk, Yusuf; Beskonakli, EthemThe objective of this study was to assess the clinical and electrophysiological changes before and after surgery in 44 patients who underwent surgical intervention due to the diagnosis of carpal tunnel syndrome (CTS). Patients who were diagnosed with a slight, moderate, and severe idiopathic CTS were assessed clinically and by electrophysiological tests before (mean 2-4 weeks) and after surgery (at sixth month). Improvement in clinical parameters was achieved more significantly than electrophysiological recovery.Öğe Evaluation of Lymphocyte Subgroups in Children With Down Syndrome(Sage Publications Inc, 2015) Yilmaz, Cahide; Dogan, Murat; Basarslan, Fatmagul; Yilmaz, Nebi; Yuca, Sevil; Bulan, Keziban; Kaya, AvniIn this study, lymphocyte subgroups including blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were analyzed in children with Down syndrome (DS). The study includes 85 children with DS, followed at Department of Pediatrics, Faculty of Medicine, Yuzuncu Yil University and 64 healthy age-matched control participants. Blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were examined in both the groups. Significantly decreased blood CD3, CD4, and CD19 values were found in the study group (P < .05) when compared with the control group. In conclusion, we would like to emphasize that blood CD3, CD4, and CD19 levels were found to be decreased in children with DS. Based on these finding, we think that these decreased lymphocyte subgroups might be responsible for increased susceptibility to infections in children with DS.Öğe Giant calvarial meningioma which obliterated superior sagittal sinus: Case report(2012) Altaş, Murat; Aras, Mustafa; Bayaro?ullari, Hanifi; Karcio?lu, Murat; Serarslan, Yurdal; Yilmaz, NebiInterosseous meningioma, defined as meningiomas confined to the skull with no epidural or subcutaneous component, is a rarely encountered example of the primary meningiomas. It is usually a benign tumour and takes origin from arachnoids cap cells. Several etiological hypotheses have been asserted for interosseous meningiomas up to the present. The literature pointed out that the symptoms of the patients with meningiomas might vary. The findings of osteolysis and hyperostosis might also be seen by X-Ray radiograph imaging. Our case was a male and 21 years old. He admitted the polyclinics of neurosurgery with the complaint of convulsion. Intracranial component of the meningioma was measured as 90 × 42 mm in MRI. Imaging indicated that this was a giant calvarium meningioma which diffusely skirted along to suture lines and obliterated superior sagittal sinus in a wide area. Clinical and radiological properties of the tumour were evaluated, and the responsible mechanisms from its pathogenesis are discussed in the light of the literature. © 2012 OMU.Öğe Intracranial meningiomas: Two-years experience of Mustafa Kemal University(Ondokuz Mayis Universitesi, 2013) Özgür, Tümay; Altas, Murat; Aras, Mustafa; Atik, Esin; Yaldiz, Mehmet; Yilmaz, NebiMeningiomas are the most common type of brain tumors. We have analyzed clinical, radiological and pathological characteristics of meningiomas that were diagnosed and operated in our centre. Twenty three meningioma cases operated in our hospital between 2010-2012 were reviewed retrospectively. Sixteen (69.1%) of cases were female and 7 (30.9%) of cases were male. The age range was 22-75. The most common symptoms of patients were headache, seizure, nausea and vomitting. Localizations of tumors were falx, cortex, sphenoid wing, posterior fossa-tentorium, olphactor, and sulcus. The surgical sizes were graded according to Simpson classification and 16 (69.1%) of cases were Grade 2 and 7 (30.9%) of cases were Grade I. At the histopathological examination; meningotheliomatous type was the most common type followed by fibrous, angiomatous, transitional, psammomatous and atypical types. Meningiomas are usually benign tumors with good prognosis which are often encountered in daily pathology and neurosurgery practice. © 2013 OMU.Öğe Metastatic Myxoid Liposarcoma of the Scalp: Case Report(Ortadogu Ad Pres & Publ Co, 2012) Kiymaz, Nejmi; Yilmaz, Nebi; Gudu, Burhan Oral; Demir, Ismail; Gokalp, AbdulsematLiposarcomas are the second most frequent soft tissue sarcomas occurring in adults after malignant fibrous histiocytomas; however, liposarcomas rarely occur on the scalp. A mass was detected on the hairy skin of a 38-year-old male patient who had undergone surgery for a mass on the posterior aspect of the right thigh and had been diagnosed with a myxoid liposarcoma 3 years earlier. The patient had undergone total bulk excision and the histopathologic examination of the mass lesion revealed liposarcoma metastasis. Chemotherapy was initiated. Relapse or metastasis did not develop during 3 years of follow-up. Here we present a patient with a myxoid liposarcoma, which metastasized from the posterior side of the right thigh to the scalp.Öğe Prognostic Factors in Patients with Occipital Encephalocele(Karger, 2010) Kiymaz, Nejmi; Yilmaz, Nebi; Demir, Ismail; Keskin, SiddikBackground: An encephalocele is a herniation of the brain and the meninges through a skull defect protruding towards the exterior. The condition is not rare when compared to spinal dysraphisms, but the worldwide incidence is not precisely known. The cases involving occipital encephaloceles which we have diagnosed in our clinic and the surgical approaches for this rare condition are presented herein. Methods: Thirty patients who were diagnosed with occipital encephaloceles and referred to our Neurosurgery Clinic at the Yuzuncu Yil University, Faculty of Medicine Research Hospital between 2000 and 2009 were enrolled in this study. The age of the patient, size of the sac, pathologies that accompanied the condition, and treatments applied were assessed. Results: In the present study, 30 patients (22 girls and 8 boys), whose ages varied between newborn and 14 months, were evaluated. The encephalocele sac was located in the occipital region in 27 patients (90%) and in the occipitocervical region in 3 patients (3%). Nine (30%) of the 30 patients died; 2 in the preoperative period, 2 in the postoperative early period (0-7 days) and 5 in the late postoperative period first week to 3 months). With the exception of the 2 patients who died preoperatively, surgery was performed on all of the patients. The mortality rate in our study was 29%. Conclusions: Our study demonstrated that factors which determine the prognosis of patients diagnosed with occipital encephaloceles include the size of the sac, the contents of the neural tissue, hydrocephaly, infections, and pathologies that accompany the condition. An occipital encephalocele is a congenital neurologic condition with an extremely high morbidity and mortality in spite of the treatments rendered pre- and postoperatively. Copyright (C) 2010 S. Karger AG, BaselÖğe Protective effects of tadalafil on experimental spinal cord injury in rats(Elsevier Sci Ltd, 2010) Serarslan, Yurdal; Yonden, Zafer; Ozgiray, Erkin; Oktar, Sueleyman; Guven, Esref Oguz; Sogut, Sadik; Yilmaz, NebiTadalafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Nitric oxide (NO) functions as a retrograde neurotransmitter in the spinal cord, and postsynaptic structures respond to NO by producing cGMP. The concentrations of cGMP in the spinal cord are controlled by the actions of PDE. The aim of the study was to evaluate and compare the effects of the use of both methylprednisolone and tadalafil on serum and tissue concentrations of NO, malondialdehyde (MDA) levels, superoxide dismutase (SOD) activity, and tissue glutathione peroxidase (GSH-Px) activity in rats with spinal cord injury (SCI). SCI was induced in Wistar albino rats by dropping a 10 g rod from a 5.0 cm height at T8-10. The 28 rats were randomly divided into four equal groups: tadalafil, methylprednisolone, non-treatment and sham groups. Rats were neurologically tested at 24 hours after trauma. At the end of the experiment, blood samples were collected and spinal cord tissue samples were harvested for biochemical evaluation. The tissue level of NO was increased in the tadalafil group compared with the non-treatment and methylprednisolone groups (p < 0.05). The tissue levels of SOD and GSH-Px did not differ between the groups. Serum levels of NO were higher in the tadalafil group than in the non-treatment group (p < 0.05). The increase in serum SOD levels was greater in the tadalafil group than the methylprednisolone group. Serum MDA levels in the tadalafll and methylprednisolone groups tended to be lower than in the non-treatment group (p > 0.05). Tissue MDA levels in the taclalafil and methylprednisolone groups tended to be lower than in the non-treatment group and sham groups (p > 0.05). Although there was no difference in neurological outcome scores between the taclalafil, methylprednisolone and non-treatment groups (p > 0.05), the animals in the taclalafil and methylprednisolone groups tended to have better Scores than the non-treatment group. Thus, tadalafil appears to be beneficial in reducing the effects of injury to the spinal cord by increasing tissue levels of NO and serum activity of SOD. (C) 2009 Elsevier Ltd. All rights reserved.
