Yazar "Zorba, Orhan U." seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Association Between Prostate Volume and Red Cell Distribution Width
    (Wiley, 2014) Zorba, Orhan U.; Uzun, Hakki; Onem, Kadir; Cetinkaya, Mehmet; Rifaioglu, Murat; Akca, Nezih
    ObjectivesTo evaluate relation between red cell distribution width (RDW) and benign prostatic hyperplasia (BPH). MethodsThe overall study population consisted of 942 men with lower urinary tract symptoms (LUTS), ranging in age from 60 to 85years old. Patients with disorder or medication that can influence lower urinary tract or erythrocytes were excluded from the study. The relationship between RDW, white blood cell (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and prostate volume, International Prostate Symptom Score (IPSS) were assessed with multivariate linear regression model. Patients were analyzed in four groups stratified according to the quartiles of prostate volume. The one-way analysis of variance (anova) was used to compare RDW, WBC CRP, and ESR between different quartiles of prostate volume. ResultsA graded and independent association of RDW with the prostate volume was identified (P=0.001). RDW was significantly associated with prostate volume in multivariate linear regression model that was adjusted for age and hemoglobin. IPSS was significantly correlated with RDW, CRP and ESR. However significance was lost after adjustment for age and prostate volume. The RDW was significantly associated with the surgical treatment in the multivariate linear regression model that was adjusted for age and prostate volume. ConclusionsA correlation between an increased RDW and prostate volume was suggested by the new data from this study. This relation may be a consequence of inflammatory stress arising from BPH. The significant association between the easy, inexpensive RDW may provide a rational basis to include the RDW in algorithms for surgery risk prediction.
  • Küçük Resim
    Öğe
    Is There a Relation between Reticular Formation and Storage Symptoms in Men
    (Wiley, 2014) Zorba, Orhan U.; Kirbas, Serkan; Uzun, Hakki; Onem, Kadir; Cetinkaya, Mehmet; Rifaioglu, Mehmet M.
    ObjectiveTo reveal brainstem originated pathology in men with different types of lower urinary tract symptoms blink reflex latency times were assessed. MethodsA total of 32 men, 16 with storage and 16 with voiding symptoms, were enrolled in the study. Blink reflex latency times were analyzed through electrical stimulation of the supraorbital nerve. Two responses in the orbicularis oculi muscle were recorded: the latency times for the early ipsilateral response, R1, and the late bilateral responses, R2. ResultsThe mean ages of the patients with storage and voiding symptoms were 57.316.87 and 58.06 +/- 6.29years, respectively. The R2 latency times were significantly longer in men with storage symptoms. However, the R1 latency times were similar for the two groups. ConclusionLate blink latency times were long only in patients who had storage symptoms. An oligosynaptic path through the trigeminal nuclei, which includes one or two interneurons, is responsible for early response; however, late response is relayed through a polysynaptic path, including neurons in the reticular formation. It has also been shown that stimulation of the pontine reticular formation inhibits the micturition contraction. In some patients, storage symptoms may result from pathology that originates with the reticular formation and this pathology may lead to increases in late blink latency times. Additional studies are needed on other reflexes that are mediated through reticular formation, in order to show the possible dysfunction of the reticular formation in men with storage symptoms.