Low bilirubin levels are associated with coronary slow flow phenomenon

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dc.contributor.authorOz, Fahrettin
dc.contributor.authorCizgici, Ahmet Yasar
dc.contributor.authorKaya, Mehmet Gungor
dc.contributor.authorKurt, Mustafa
dc.contributor.authorBasibuyuk, Murat
dc.contributor.authorTufan, Fatih
dc.contributor.authorOflaz, Huseyin
dc.date.accessioned2024-09-18T20:04:25Z
dc.date.available2024-09-18T20:04:25Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground and aim: Increasing evidence suggests an inverse relationship between bilirubin levels and cardiovascular disease. The present study evaluated the effect of bilirubin level on the slow coronary flow (SCF) phenomenon. Methods: This study was cross-sectional and observational. We enrolled 222 consecutive patients who underwent coronary angiography for suspected ischaemic heart disease and were found to have normal or near-normal coronary arteries. Then, bilirubin levels were measured and coronary flow rate was assessed using the thrombolysis in myocardial infarction (TIMI) frame count. SCF was defined as a TIMI frame count > 27 frames. Results: SCF was observed in at least one coronary vessel in 22 of the 222 subjects, indicating a prevalence of 10%. Serum bilirubin levels were significantly decreased in the SCF group. In multivariate logistic regression analysis, total bilirubin and diabetes mellitus were independent risk factors for SCF. Furthermore, after adjusting for age, sex, and cardiovascular disease risk factors, serum bilirubin level (B = -0.34, p < 0.001) was independently associated with TIMI frame count. Conclusions: These findings suggest that serum total bilirubin levels may be a useful marker for patients with the SCF phenomenon. We believe that further studies are needed to clarify the role of bilirubin in patients with SCF.en_US
dc.identifier.doi10.5603/KP.a2014.0117
dc.identifier.endpage45en_US
dc.identifier.issn0022-9032
dc.identifier.issn1897-4279
dc.identifier.issue1en_US
dc.identifier.pmid25765055en_US
dc.identifier.scopus2-s2.0-84921698050en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage40en_US
dc.identifier.urihttps://doi.org/10.5603/KP.a2014.0117
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8155
dc.identifier.volume73en_US
dc.identifier.wosWOS:000348808200006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPolskie Towarzystowo Kardiologiczneen_US
dc.relation.ispartofKardiologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectbilirubinen_US
dc.subjectendothelial dysfunctionen_US
dc.subjectslow coronary flowen_US
dc.subjectTIMI frame counten_US
dc.subjectatherosclerosisen_US
dc.titleLow bilirubin levels are associated with coronary slow flow phenomenonen_US
dc.typeArticleen_US

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