Markers of inflammation as determinants of mortality in intensive care unit patients

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Date

2007

Journal Title

Journal ISSN

Volume Title

Publisher

Springer

Access Rights

info:eu-repo/semantics/closedAccess

Abstract

In this study, the investigators explored the relationship between mortality rate and serum levels of C-reactive protein (CRP), erythrocyte sedimentation ratio (ESR), albumin, and hemoglobin, leukocyte, and platelet counts of patients at the time of first admission to the intensive care unit (ICU). A total of 123 patients were admitted to 2 different ICUs. In the emergency departments, serum levels of CRP, ESR, and albumin and hematologic parameters of 81 patients who died and were 42 patients who survived were compared. Student t test and the chi(2) test were used for statistical analyses. Mean CRP and ESR levels and leukocyte counts were higher in nonsurvivor than in survivor groups (P<.001 for all). Additionally, serum CRP and ESR elevations and leukocyte counts were determined to be individually related to mortality (P<.001, P<.05, and P<.05, respectively). The investigators concluded that initial serum levels of CRP and ESR and leukocyte counts can be used as determinants of mortality in ICU patients.

Description

Keywords

intensive care, mortality rate, C-reactive protein, erythrocyte sedimentation rate, hemoglobin, leukocyte count, platelet count

Journal or Series

Advances in Therapy

WoS Q Value

Q4

Scopus Q Value

Q1

Volume

24

Issue

5

Citation