A novel electrospun nano-fabric graft allows early cannulation access and reduces exposure to central venous catheters

Simple item page
dc.contributor.authorKaratepe, Celalettin
dc.contributor.authorAltinay, Levent
dc.contributor.authorYetim, Tulin Durgun
dc.contributor.authorDagli, Celaleftin
dc.contributor.authorDursun, Suat
dc.date.accessioned2024-09-18T20:02:39Z
dc.date.available2024-09-18T20:02:39Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: The use of tunneled central venous catheters (CVC) as vascular access for hemodialysis treatment is increasing worldwide. We present a novel polycarbonate urethane nano-fabric graft, produced by electrospinning technology, which has self-sealing features that avoid seroma formation and allow puncturing within 48 hours. The aim of this study was to assess its advantages in a setting where late referral is common. Methods: A retrospective single center study assessed 24 implanted grafts in 24 patients with maximal follow-up of 18 months; patency rates, time to first cannulation and post-operative complications were assessed. Results: Successful access was achieved in all 24 patients within 48 hours. In 50% of the patients cannulation was performed within 24 hours without increasing the complication rate. Twelve month primary and secondary patencies were 50% and 70.8%, respectively. Excluding early failures (within 30 days) because of surgical problems, 12 month primary and secondary patencies were 75% and 81.2% respectively. Complication and infection rates were 10.94 and 0.49/1000 dialysis procedures, respectively. No pseudoaneurysms or seromas were documented at 18 months. Conclusions: Early cannulation was successful in all patients with good 12-month primary and secondary patency rates, compared to data reported by others on polytetrafluoroethylene (PTFE) grafts. The infection rate was substantially lower than in tunneled CVCs. Therefore, the AVflo graft may improve the clinical status of dialysis patients by decreasing the exposure to CVCs.en_US
dc.identifier.doi10.5301/jva.5000145
dc.identifier.endpage280en_US
dc.identifier.issn1129-7298
dc.identifier.issn1724-6032
dc.identifier.issue3en_US
dc.identifier.pmid23599141en_US
dc.identifier.scopus2-s2.0-84885804556en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage273en_US
dc.identifier.urihttps://doi.org/10.5301/jva.5000145
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7937
dc.identifier.volume14en_US
dc.identifier.wosWOS:000328803700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of Vascular Accessen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArterio-Venous-Accessen_US
dc.subjectClinical studyen_US
dc.subjectEarly accessen_US
dc.subjectElectrospinningen_US
dc.subjectHemodialysis graften_US
dc.subjectNano-fabricen_US
dc.subjectPolycarbonate urethaneen_US
dc.titleA novel electrospun nano-fabric graft allows early cannulation access and reduces exposure to central venous cathetersen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
[ N/A ]
Name:
Tam Metin / Full text
Size:
178.61 KB
Format:
Adobe Portable Document Format
Download

Collections

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu