Corneal biomechanical parameters in systemic autoimmune diseases

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dc.authoridOzarslan Ozcan, Deniz/0000-0003-2814-1975
dc.authoridozcan, sait coskun/0000-0002-0608-9371
dc.contributor.authorOzarslan Ozcan, Deniz
dc.contributor.authorOzcan, Sait Coskun
dc.contributor.authorKimyon, Gezmis
dc.date.accessioned2024-09-18T19:54:24Z
dc.date.available2024-09-18T19:54:24Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground This study aims to evaluate corneal biomechanical changes in patients with systemic autoimmune diseases using Corvis ST. Methods This prospective study included 36 patients with ankylosing spondylitis (AS), 38 patients with rheumatoid arthritis (RA), and 36 age- and sex-matched healthy subjects. After ophthalmologic examinations Pentacam HR and Corvis ST was performed on all eyes. The mean keratometric and pachymetric data, corneal biomechanical parameters, biomechanical intraocular pressure (bIOP) were analysed. Results There was no statistically significant differences among the groups regarding age, gender, refraction, visual acuity, IOP, pachymetry and keratometry. Compared to healthy controls, the mean velocity values of applanation 1 (A1V) and 2 (A2V), deformation amplitude (DA), and corvis biomechanical index (CBI) were statistically significantly higher and stiffness parameter at first applanation (SPA1) was statistically significantly lower in AS and RA patients (all p < 0.05). In both AS and RA groups, disease duration was found to be negatively correlated with SPA1 (p = 0.043, 0.027, respectively) and positively correlated with CBI (p = 0.022, 0.020, respectively). Conclusion AS and RA patients have a decreased corneal stiffness compared to healthy subjects. Disease duration seems to be correlated with these changes.en_US
dc.identifier.doi10.1080/08164622.2021.1896335
dc.identifier.endpage64en_US
dc.identifier.issn0816-4622
dc.identifier.issn1444-0938
dc.identifier.issue1en_US
dc.identifier.pmid33719873en_US
dc.identifier.scopus2-s2.0-85102683481en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage61en_US
dc.identifier.urihttps://doi.org/10.1080/08164622.2021.1896335
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7712
dc.identifier.volume105en_US
dc.identifier.wosWOS:000629066100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofClinical and Experimental Optometryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing spondylitisen_US
dc.subjectcorneal biomechanicsen_US
dc.subjectCORVIS STen_US
dc.subjectrheumatoid arthritisen_US
dc.titleCorneal biomechanical parameters in systemic autoimmune diseasesen_US
dc.typeArticleen_US

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