Evaluation of the mean platelet volume in children with familial Mediterranean fever

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dc.authoridkarakus, ali/0000-0003-1358-3201
dc.contributor.authorArica, Secil
dc.contributor.authorOzer, Cahit
dc.contributor.authorArica, Vefik
dc.contributor.authorKarakus, Ali
dc.contributor.authorCelik, Tanju
dc.contributor.authorGunesacar, Ramazan
dc.date.accessioned2024-09-18T20:20:00Z
dc.date.available2024-09-18T20:20:00Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractTo evaluate the Mean Platelet Volume (MPV) levels in children diagnosed with familial Mediterranean fever (FMF), during attack and attack-free periods. The records of a total of 117 children with FMF, diagnosed using the Tel-Hashomer criteria, have been scanned. The study consisted of 53 patients during an attack (group 1), 64 patients in attack-free period (group 2), and 57 healthy controls (group 3). Erythrocyte sedimentation rate, C-reactive protein, white blood cell count, platelet count, and MPV levels were retrospectively recorded. The MPV and platelet values in FMF patients during attack (group 1) and FMF patients during attack-free periods (group 2) have been found to be significantly higher than those of the health control group (group 3). Positive correlation has been found between the MPV and platelet values in Group 1 and the disease's severity score (r = 0.224, and r = 0.268, respectively). Positive correlation (r = 0.528, and r = 0.485, respectively) has been also identified between MPV and blood platelet count in patients in Group 1 and 2. No correlation was found between the Colchicine treatment period and MPV (r = -0.005). The MPV values in the complete group of FMF diagnosed children have been found to be much higher compared to those in healthy children. As a consequence, we consider the MPV value as a useful marker that demonstrates the risk of early stage atherosclerosis in children with FMF.en_US
dc.identifier.doi10.1007/s00296-011-2251-x
dc.identifier.endpage3563en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue11en_US
dc.identifier.pmid22086472en_US
dc.identifier.scopus2-s2.0-84872189949en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3559en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-011-2251-x
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10002
dc.identifier.volume32en_US
dc.identifier.wosWOS:000311515300032en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectAtherosclerosisen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlateleten_US
dc.titleEvaluation of the mean platelet volume in children with familial Mediterranean feveren_US
dc.typeArticleen_US

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