Citric acid production by yarrowia lipolytica

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dc.authorscopusid57197835538
dc.authorscopusid6603735587
dc.authorscopusid6507014982
dc.authorscopusid57190060795
dc.authorscopusid7003689633
dc.contributor.authorCarsanba, Erdem
dc.contributor.authorPapanikolaou, Seraphim
dc.contributor.authorFickers, Patrick
dc.contributor.authorAgirman, Bilal
dc.contributor.authorErten, Huseyin
dc.date.accessioned2024-09-19T15:45:33Z
dc.date.available2024-09-19T15:45:33Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractRecently, with an increasing annual demand of more than two million tons, citric acid (CA) has become the main additive and functional component in the food, pharmaceutical, and chemical industries. This rising demand has induced research to search for alternative and cheap ways to fulfil CA requirements in industry. Lately, Yarrowia lipolytica has been considered as a promising microorganism in the production of CA since it has many advantages over moulds: mainly high productivity, easier cultivation (convenient for continuous process), and the capability to use a wide range of agricultural or industrial by-products and wastes as cheap carbon sources. CA production by this yeast depends on certain factors such as medium composition (type and concentrations of carbon, nitrogen, and trace elements) and the type of strain used (wild, mutant, or genetically engineered), as well as cultivation conditions (pH, temperature, dissolved oxygen, etc.). This review principally details recent studies concerning CA production by Y. lipolytica with an emphasis on techniques to increase productivity and yield to meet the expanding demand for this organic acid. Suitable substrates and production factors for high and cost-efficient CA production are discussed. Downstream processes and production systems are also reviewed. © Springer Nature Switzerland AG 2019.en_US
dc.identifier.doi10.1007/978-3-030-21110-3_4
dc.identifier.endpage117en_US
dc.identifier.isbn978-303021110-3
dc.identifier.isbn978-303021110-0
dc.identifier.scopus2-s2.0-85085427686en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.1007/978-3-030-21110-3_4
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14759
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer International Publishingen_US
dc.relation.ispartofNon-conventional Yeasts: from Basic Research to Applicationen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCitric aciden_US
dc.subjectCitric acid biosynthesisen_US
dc.subjectFactorsen_US
dc.subjectYarrowia lipolyticaen_US
dc.subjectYeasten_US
dc.titleCitric acid production by yarrowia lipolyticaen_US
dc.typeBook Chapteren_US

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