Addition of Ketamine to Propofol-Alfentanil Anesthesia May Reduce Postoperative Pain in Laparoscopic Cholecystectomy

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dc.contributor.authorKarcioglu, Murat
dc.contributor.authorDavarci, Isil
dc.contributor.authorTuzcu, Kasim
dc.contributor.authorBozdogan, Yusuf B.
dc.contributor.authorTurhanoglu, Selim
dc.contributor.authorAydogan, Akin
dc.contributor.authorTemiz, Muhyittin
dc.date.accessioned2024-09-18T20:28:15Z
dc.date.available2024-09-18T20:28:15Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to assess whether intravenous anesthesia supplemented with ketamine reduces postoperative pain after elective laparoscopic cholecystectomy. Materials and Methods: Forty patients were enrolled and randomized 1: 1 into one of 2 groups: the propofol group (received propofol and alfentanil supplemented with saline) and the ketamine group (received propofol and alfentanil with ketamine). The study was double-blind. The number and amount of the intraoperative additional alfentanil doses were recorded. Pain assessments and cumulative analgesic consumption at postanesthesia care unit (PACU) admission, PACU discharge, postoperative 24th hour, and hospital discharge were recorded. Results: The visual analog scale scores at PACU admission, PACU discharge, postoperative 24th hour, and hospital discharge were significantly lower in the ketamine group than the propofol group. The pain visual analog scale >= 75 at the postoperative 24th hour for the propofol group was also significantly lower (P < 0.035) than that of the ketamine group. The difference in analgesic consumption between groups was statistically significant (P < 0.001). Conclusions: Our study showed that ketamine supplemented with propofol and alfentanil produced better analgesia intraoperatively and postoperatively and decreased analgesic consumption compared with the propofol group after laparoscopic cholecystectomy.en_US
dc.identifier.doi10.1097/SLE.0b013e3182827f09
dc.identifier.endpage202en_US
dc.identifier.issn1530-4515
dc.identifier.issue2en_US
dc.identifier.pmid23579518en_US
dc.identifier.scopus2-s2.0-84876448723en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://doi.org/10.1097/SLE.0b013e3182827f09
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10813
dc.identifier.volume23en_US
dc.identifier.wosWOS:000317583900030en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofSurgical Laparoscopy Endoscopy & Percutaneous Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectketamineen_US
dc.subjectpropofolen_US
dc.subjectpostoperative painen_US
dc.subjectlaparoscopic cholecystectomyen_US
dc.titleAddition of Ketamine to Propofol-Alfentanil Anesthesia May Reduce Postoperative Pain in Laparoscopic Cholecystectomyen_US
dc.typeArticleen_US

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