The relationship between ghrelin and adiponectin levels in breast milk and infant serum and growth of infants during early postnatal life

Basit Öğe Kaydı
dc.authoridDundar, Bumin N/0000-0002-7506-061X
dc.contributor.authorCesur, Gokhan
dc.contributor.authorOzguner, Fehmi
dc.contributor.authorYilmaz, Nigar
dc.contributor.authorDundar, Bumin
dc.date.accessioned2024-09-18T20:06:12Z
dc.date.available2024-09-18T20:06:12Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractGhrelin and adiponectin have been found in breast milk and are considered to take part in the regulation of growth and energy metabolism of infants. Our aims were to determine ghrelin and adiponectin levels in breast milk and serum samples of mothers and their infants, and to investigate the relationship between their levels and anthropometry of newborn infants during early postnatal life. Total and active ghrelin and adiponectin levels were studied in breast milk, and the serum samples of 25 healthy lactating women and their healthy fullterm infants were taken at the 1st and 4th months of life. Anthropometric measurements of infants were also performed during the study period. Breast milk and infant serum active ghrelin levels were found to be significantly increased at the 4th month of life compared with 1st month levels (p < 0.05). Maternal serum total ghrelin and infant serum adiponectin levels were found to be significantly reduced at the 4th month of life (p < 0.05). Breast milk active ghrelin levels were higher than the infant and maternal serum active ghrelin at the 1st and 4th months (p < 0.05). There was a negative significant correlation between the level of infant serum active ghrelin levels and BMI of infants at the 1st month. A positive significant correlation was found between the level of 1st month infant serum adiponectin levels and weight gain of infants during the study period. Fourth month infant serum adiponectin were also positively correlated with weight and BMI of infants at the 4th month and the weight gain during study period. There was a positive significant correlation between the level of 4th month breast milk active ghrelin and weight gain of infants during the study period. Ghrelin and adiponectin are involved in postnatal growth of infants. Ghrelin in breast milk also seems to be related to the growth of infants during early postnatal life. The sources of these peptides in breast milk are probably both maternal serum and breast tissue itself.en_US
dc.identifier.doi10.1007/s12576-012-0193-z
dc.identifier.endpage190en_US
dc.identifier.issn1880-6546
dc.identifier.issn1880-6562
dc.identifier.issue3en_US
dc.identifier.pmid22311236en_US
dc.identifier.scopus2-s2.0-84860711518en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage185en_US
dc.identifier.urihttps://doi.org/10.1007/s12576-012-0193-z
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8375
dc.identifier.volume62en_US
dc.identifier.wosWOS:000303453400004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Japan Kken_US
dc.relation.ispartofJournal of Physiological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast milken_US
dc.subjectGhrelinen_US
dc.subjectAdiponectinen_US
dc.subjectInfanten_US
dc.subjectGrowthen_US
dc.titleThe relationship between ghrelin and adiponectin levels in breast milk and infant serum and growth of infants during early postnatal lifeen_US
dc.typeArticleen_US

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