INVESTIGATION OF VITAMIN D LEVELS IN PATIENTS WITH INACTIVE HEPATITIS B VIRUS CARRIER

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dc.authoridDokuyucu, Recep/0000-0001-6837-3477
dc.contributor.authorMotor, Sedat
dc.contributor.authorKoksaldi-Motor, Vicdan
dc.contributor.authorDokuyucu, Recep
dc.contributor.authorUstun, Ihsan
dc.contributor.authorEvirgen, Omer
dc.contributor.authorYilmaz, Nigar
dc.contributor.authorOnlen, Yusuf
dc.date.accessioned2024-09-18T20:26:40Z
dc.date.available2024-09-18T20:26:40Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractObjective: The purpose of the present study was to investigate vitamin D levels in inactive hepatitis B virus carriers. Materials and methods: A total of 81 patients with inactive hepatitis B virus carrier state were enrolled at the study. Serum calcium (Ca++), phosphorus (PO4), total protein, albumin, parathormone (PTH) and 25-hydroxy vitamin D (25OHD) were determined. Serum vitamin D concentration was classified as lacking when it was less than 50 nmolll (20 ng/ml), insufficient when it was 52.5-72.5 nmol/l (21-29 ng/ml), and sufficient when it was more than 75 nmol/l (30-100 ng/ml). Results: The mean 25OHD level was found to be 131.7 +/- 50.0 nmol/l. Deficiency and insufficiency was seen in one (1.2 %) and nine (11.1 %) inactive hepatitis B virus carriers, respectively. All the patients have normal serum PTH and albumin levels. Total Ca++ and PO4 were low in ten and eight patients, respectively (p<0.05). Conclusion: Vitamin D may cause the stimulation of antiviral immune response and a preventive effect on necroinflammation and liver fibrosis. Therefore, it may affect course of HBV infection. The new studies with larger sample are needed to research the role of vitamin D in the course of chronic HBV infection, liver failure, cirrhosis, and hepatocellular carcinoma.en_US
dc.identifier.endpage796en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue4en_US
dc.identifier.startpage793en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10473
dc.identifier.volume30en_US
dc.identifier.wosWOS:000344634300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis B virus infectionen_US
dc.subjectImmunityen_US
dc.subjectInactive carrieren_US
dc.subjectVitamin Den_US
dc.titleINVESTIGATION OF VITAMIN D LEVELS IN PATIENTS WITH INACTIVE HEPATITIS B VIRUS CARRIERen_US
dc.typeArticleen_US

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