The protective effects of the Lactarius deliciosus and Agrocybe cylindracea mushrooms on histopathology of carbon tetrachloride induced oxidative stress in rats

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dc.authoridKELES, OMER FARUK/0000-0002-7869-5311
dc.authoriddogan, abdulahad/0000-0002-5438-8560
dc.authoridUyar, Ahmet/0000-0003-4345-6756
dc.contributor.authorDogan, Abdulahad
dc.contributor.authorUyar, Ahmet
dc.contributor.authorHasar, Songul
dc.contributor.authorKeles, Omer Faruk
dc.date.accessioned2024-09-18T19:47:58Z
dc.date.available2024-09-18T19:47:58Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWe investigated the protective effects of L. deliciosus and A. cylindracea supplementation against carbon tetrachloride (CCI4) induced oxidative stress by measuring levels of adenosine deaminase (ADA) and myeloperoxidase (MPO), and by observing histopathological changes in liver and kidney tissues of rats. We divided 36 rats into six groups: control, CCl4, L. deliciosus, A. cylindracea, CCl4 + L. deliciosus, and CCl4 + A. cylindracea. We found that administration of CCI4, A. cylindracea, and CCl4 + A. cylindracea increased MPO and ADA levels. We observed severe hepato-renal degenerative and necrotic lesions in the CCI4, A. cylindracea and CCl4 + A. cylindracea groups. Severe lesions of the liver and kidney were not observed with A. cylindracea administration. CCI4 induced hepato-renal lesions were ameliorated by L. deliciosus extract supplementation. L. deliciosus could be an important dietary antioxidant for preventing histologic lesions in liver and kidney due to CCI4 induced oxidative stress in rats.en_US
dc.description.sponsorshipVan Yuzuncu Yil University Scientific Research Project Commission [2015-FBE -YL150]en_US
dc.description.sponsorshipThis work was funded by the Van Yuzuncu Yil University Scientific Research Project Commission [Grant no: 2015-FBE -YL150].en_US
dc.identifier.doi10.1080/10520295.2021.1918349
dc.identifier.endpage151en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue2en_US
dc.identifier.pmid33970727en_US
dc.identifier.scopus2-s2.0-85105969388en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.1080/10520295.2021.1918349
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7263
dc.identifier.volume97en_US
dc.identifier.wosWOS:000648850100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAen_US
dc.subjectcylindraceaen_US
dc.subjectcarbon tetrachlorideen_US
dc.subjecthistopathologyen_US
dc.subjectLen_US
dc.subjectdeliciosusen_US
dc.subjectmushroomsen_US
dc.subjectoxidative stressen_US
dc.subjectratsen_US
dc.titleThe protective effects of the Lactarius deliciosus and Agrocybe cylindracea mushrooms on histopathology of carbon tetrachloride induced oxidative stress in ratsen_US
dc.typeArticleen_US

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