Investigating the effect of STN-DBS stimulation and different frequency settings on the acoustic-articulatory features of vowels

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dc.authoridYILMAZ, Atilla/0000-0002-1081-3545
dc.contributor.authorYilmaz, Atilla
dc.contributor.authorSarac, Elif Tugba
dc.contributor.authorAydinli, Fatma Esen
dc.contributor.authorYildizgoren, Mustafa Turgut
dc.contributor.authorOkuyucu, Emine Esra
dc.contributor.authorSerarslan, Yurdal
dc.date.accessioned2024-09-18T20:15:02Z
dc.date.available2024-09-18T20:15:02Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction Parkinson's disease (PD) is the second most frequent progressive neuro-degenerative disorder. In addition to motor symptoms, nonmotor symptoms and voice and speech disorders can also develop in 90% of PD patients. The aim of our study was to investigate the effects of DBS and different DBS frequencies on speech acoustics of vowels in PD patients. Methods The study included 16 patients who underwent STN-DBS surgery due to PD. The voice recordings for the vowels including [a], [e], [i], and [o] were performed at frequencies including 230, 130, 90, and 60 Hz and off-stimulation. The voice recordings were gathered and evaluated by the Praat software, and the effects on the first (F1), second (F2), and third formant (F3) frequencies were analyzed. Results A significant difference was found for the F1 value of the vowel [a] at 130 Hz compared to off-stimulation. However, no significant difference was found between the three formant frequencies with regard to the stimulation frequencies and off-stimulation. In addition, though not statistically significant, stimulation at 60 and 230 Hz led to several differences in the formant frequencies of other three vowels. Conclusion Our results indicated that STN-DBS stimulation at 130 Hz had a significant positive effect on articulation of [a] compared to off-stimulation. Although there is not any statistical significant stimulation at 60 and 230 Hz may also have an effect on the articulation of [e], [i], and [o] but this effect needs to be investigated in future studies with higher numbers of participants.en_US
dc.identifier.doi10.1007/s10072-018-3479-y
dc.identifier.endpage1689en_US
dc.identifier.issn1590-1874
dc.identifier.issn1590-3478
dc.identifier.issue10en_US
dc.identifier.pmid29938340en_US
dc.identifier.scopus2-s2.0-85049041161en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1683en_US
dc.identifier.urihttps://doi.org/10.1007/s10072-018-3479-y
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9404
dc.identifier.volume39en_US
dc.identifier.wosWOS:000445425200003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer-Verlag Italia Srlen_US
dc.relation.ispartofNeurological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDeep brain stimulationen_US
dc.subjectSubthalamic nucleusen_US
dc.subjectSpeechen_US
dc.subjectAcoustic-articulatory featuresen_US
dc.subjectParkinson's diseaseen_US
dc.subjectDBSen_US
dc.titleInvestigating the effect of STN-DBS stimulation and different frequency settings on the acoustic-articulatory features of vowelsen_US
dc.typeArticleen_US

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