Occurrence and characterization of ciprofloxacin-resistant Escherichia coli from bovine and ovine bulk tank milk samples in Turkey

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dc.authoridTekeli, Ibrahim Ozan/0000-0002-6845-2279
dc.contributor.authorKurekci, Cemil
dc.contributor.authorAydin, Muhsin
dc.contributor.authorTekeli, Ibrahim Ozan
dc.contributor.authorAmbarcioglu, Pinar
dc.contributor.authorSengul, Seydi Ahmet
dc.contributor.authorSakin, Fatih
dc.date.accessioned2024-09-18T21:05:25Z
dc.date.available2024-09-18T21:05:25Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe objective of this study was to examine the occurrence and characteristics of ciprofloxacin-resistant (Cip(R)) Escherichia coli isolates on bulk tank milk (BTM) samples (bovine and ovine origins) in Turkey. A total of 91 BTM samples (41.7%, 95% confidence intervals 35.2-48.6%) out of 218 were found to be positive for Cip(R) E. coli isolates (MIC values of >= 4 mu g/ml). Analysis of PFGE fingerprint profile for E. coli isolates resulted in the 55 different pulsotypes based on >85% homology. All isolates were resistant to enrofloxacin and nalidixic acid and the resistance rates in bovine and ovine origin isolates were 94.9 and 78.1% for norfloxacin (p < .05) and 27.1 and 34.4% for levofloxacin, respectively. Additionally, resistance to non-quinolone antibiotics was commonly observed against tetracycline (resistance rates in bovine and ovine = 91.5 and 87.5%, respectively), trimethoprim-sulfamethoxazole (83.1 and 93.8%, respectively), gentamycin (15.3 and 40.6%, respectively, p < .05) and chloramphenicol (23.7 and 65.6%, respectively, p < .05). The qnrS1 gene (3.1 and 6.8%, respectively) was the most prevalent PMQR genes in isolates from ovine and bovine origins, followed by aac (6 ')-Ib-cr (0 and 5.1%, respectively) and qnrB19 (0 and 1.7%, respectively). The other resistance genes including tetA, tetB, strA/B, aPozhA1, aadA, aadB, bla(CTX-M), and bla(TEM) were also identified in various frequencies. The most frequently observed virulence trait was fimH. The low-level presence of PMQR genes and as well as some virulence traits is an important finding, yet the results of this study are worrisome because quinolone antibiotics are still the drugs of choice for severe infections in humans.en_US
dc.description.sponsorshipHatay Mustafa Kemal University [BAP-16489]en_US
dc.description.sponsorshipWe thank cattle breeders' association of Hatay and sheep and goat breeders' association of Hatay for providing the bulk tank milk samples. This work was supported by a grant of the Hatay Mustafa Kemal University (BAP-16489).en_US
dc.identifier.doi10.1111/jfs.12881
dc.identifier.issn0149-6085
dc.identifier.issn1745-4565
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85099385236en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/jfs.12881
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13557
dc.identifier.volume41en_US
dc.identifier.wosWOS:000607407600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Food Safetyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleOccurrence and characterization of ciprofloxacin-resistant Escherichia coli from bovine and ovine bulk tank milk samples in Turkeyen_US
dc.typeArticleen_US

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