Effects of a Single Application of Extractum Cepae on the Peritendinous Adhesion An Experimental Study in Rabbits

Basit Öğe Kaydı
dc.contributor.authorDogramaci, Yunus
dc.contributor.authorKalacı, Aydıner
dc.contributor.authorAtik, Esin
dc.contributor.authorEsen, Erdinc
dc.contributor.authorAltug, Muhammet Enes
dc.contributor.authorOnel, Ercument
dc.contributor.authorKoc, Ahmet
dc.date.accessioned2024-09-18T20:19:58Z
dc.date.available2024-09-18T20:19:58Z
dc.date.issued2010
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPeritendinous adhesion is an important cause of poor functional outcome after flexor tendon repair. The objective of this study was to investigate the effect of a single intraoperative application of extractum cepae, an extract of dietary onion, on the peritendinous adhesion, using a rabbit model of flexor tendon injury. The first, second, and third digits of the right hind paw of 18 rabbits were used for tendon operations. A standard partial division of the synovial sheath and flexor tendon was done at zone II to stimulate the adhesion formation. In the treatment group (n = 9 rabbits, 27 tendons), the flexor tendon sheath was treated with 50 mg/mL of extractum cepae which was applied locally and allowed to infiltrate for 5 minutes, the skin was sutured without suturing the sheath and the tendons. The same operation was done for the control group (n = 9 rabbits, 27 tendons) and 1 mL of normal saline solution was applied locally. Biomechanical and histologic evaluations of the specimens were done after 3 weeks. Tendons from the first toes were used for biomechanical studies. The second and third toe tendons were used for histopathologic evaluation. We have compared the peritendinous adhesions and the ultimate forces in the control and treated tendons. There were no statistically significant differences between the 2 groups with respect to the ultimate loads. Adhesion formation was absent in 1 tendon (5.5%), slight in 8 (44.4%), moderate in 6 (33.3), and severe in 3 tendons (16.7%) in the extractum cepae treated group (n = 18); while in the control group (n = 18), it was absent in 1 tendon (5.5%), slight in 1 tendon (5.5%), moderate in 3 (16.6%), and severe in 13 (72.4%) tendons. There was a significant reduction (P = 0.01) in the peritendinous adhesion in the treated group comparing to the control group. The problem of adhesion formation may be minimized using a single intraoperative application of extractum cepae.en_US
dc.identifier.doi10.1097/SAP.0b013e3181afa428
dc.identifier.endpage341en_US
dc.identifier.issn0148-7043
dc.identifier.issue3en_US
dc.identifier.pmid20179487en_US
dc.identifier.scopus2-s2.0-77649242495en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage338en_US
dc.identifier.urihttps://doi.org/10.1097/SAP.0b013e3181afa428
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9978
dc.identifier.volume64en_US
dc.identifier.wosWOS:000275061800019en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnnals of Plastic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectextractum cepaeen_US
dc.subjecttendon injuryen_US
dc.subjectpreventionen_US
dc.subjectperitendinous adhesionen_US
dc.titleEffects of a Single Application of Extractum Cepae on the Peritendinous Adhesion An Experimental Study in Rabbitsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
467.85 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu