Determination of dynamic thiol-disulfide levels in dairy cattle with foot disease

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dc.contributor.authorDeveci, Mehmet Zeki Yilmaz
dc.contributor.authorErdal, Huseyin
dc.date.accessioned2024-09-18T20:15:00Z
dc.date.available2024-09-18T20:15:00Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractFoot diseases are among the top three causes of economic loss in dairy cattle. Recent studies show that oxidative stress plays a critical role in the pathogenesis of foot diseases. There is no study determining the dynamic thioldisulfide levels in dairy cattle with foot disease. This study aimed to determine dynamic thiol-disulfide levels in foot diseased and healthy dairy cattle. Demographic information about the animals, and clinical findings of foot diseases and lameness were presented. In the Foot Disease Group, native thiol (P<0.01), total thiol (P<0.05), disulfide (P<0.01), disulfide/native thiol (P<0.01) and disulfide/total thiol (P<0.01) results were found to be significantly higher than in the Control Group. Native thiol/total thiol (P<0.01) was found to be significantly higher in the Control Group than in the Foot Disease Group. As a result, statistically significant increases in thiol-disulfide levels were determined in foot diseased dairy cattle. It was shown that the thiol-disulfide balance was impaired. This study is the first to determine thiol-disulfide levels and thus changes in thiol-disulfide homeostasis in healthy and foot diseased dairy cattle. With further studies, oxidative stress changes that occur as a result of foot diseases can be better understood and the use of antioxidants as a part of treatment evaluated.en_US
dc.description.sponsorshipCoordinatorship of Scientific Research Projects of Hatay Mustafa Kemal University [20, 052]en_US
dc.description.sponsorshipAcknowledgement This study was supported by the Coordinatorship of Scientific Research Projects of Hatay Mustafa Kemal University (Project No: 20.M.052) . The authors would like to thank ?aban G?ven for his help in the fieldwork. The authors have no conflicts of interest to declare.en_US
dc.identifier.doi10.24099/vet.arhiv.1785
dc.identifier.endpage666en_US
dc.identifier.issn0372-5480
dc.identifier.issn1331-8055
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85149637415en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage657en_US
dc.identifier.urihttps://doi.org/10.24099/vet.arhiv.1785
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9365
dc.identifier.volume92en_US
dc.identifier.wosWOS:000934009800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Zagreb Vet Facultyen_US
dc.relation.ispartofVeterinarski Arhiven_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectdairy cattleen_US
dc.subjectfoot diseaseen_US
dc.subjectoxidative stressen_US
dc.subjectthiol-disulfideen_US
dc.titleDetermination of dynamic thiol-disulfide levels in dairy cattle with foot diseaseen_US
dc.typeArticleen_US

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