In vitro antileishmanial activity of Adana propolis samples on Leishmania tropica

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dc.contributor.authorDuran, G.
dc.contributor.authorDuran, N.
dc.contributor.authorCulha, G.
dc.contributor.authorOzcan, B.
dc.contributor.authorOztas, H.
dc.contributor.authorOzer, B.
dc.date.accessioned2024-09-18T21:02:55Z
dc.date.available2024-09-18T21:02:55Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPropolis (bee glue) is a natural resinous hive product, collected from various plant sources. It has attracted much attention as a useful substance applied in medicine due to its pharmacological activities. It was aimed to investigate the in vitro effects of an ethanolic extract of Adana propolis samples on the growth of Leishmania tropica. Parasite cells were treated with five concentrations (25, 50, 100, 50, 500, and 750 mu g/ml) of the propolis. The number of promastigotes in each concentration was calculated using a hemocytometer slide at 24, 48, and 72 h after being harvested. In the experiments, it was determined that the concentrations up to 100 mu g/ml of the propolis did not exhibit antileishmanial activity against the parasites cells. At these concentrations, there was no changes in terms of morphologically. In addition, there was no statistically significant difference in terms of cell count between control and these three groups (p > 0.05). However, in culture media containing the propolis samples at 250, 500, and 750-mu g/ml concentrations, statistically significant differences in cell counts were observed, as compared to the control group (p < 0.05). Our results demonstrate that ethanolic extracts of Adana propolis samples reduce the proliferation of L. tropica parasites significantly.en_US
dc.identifier.doi10.1007/s00436-008-0896-5
dc.identifier.endpage1225en_US
dc.identifier.issn0932-0113
dc.identifier.issn1432-1955
dc.identifier.issue6en_US
dc.identifier.pmid18264819en_US
dc.identifier.scopus2-s2.0-42049090617en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1217en_US
dc.identifier.urihttps://doi.org/10.1007/s00436-008-0896-5
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13134
dc.identifier.volume102en_US
dc.identifier.wosWOS:000254805400015en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofParasitology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBulgarian Propolisen_US
dc.subjectAntiviral Activityen_US
dc.subjectKeratitisen_US
dc.subjectRabbitsen_US
dc.subjectDrugsen_US
dc.subjectAntibacterialen_US
dc.subjectChemotherapyen_US
dc.subjectFlavonoidsen_US
dc.subjectBacteriaen_US
dc.subjectProgressen_US
dc.titleIn vitro antileishmanial activity of Adana propolis samples on Leishmania tropicaen_US
dc.typeArticleen_US

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