Glomerular hyperfiltration in hypogonadotropic hypogonadic patients: Overlooking a cache?

Basit Öğe Kaydı
dc.authoridGORUR, Sadik/0000-0002-3458-5428
dc.contributor.authorGozukara, Kerem Han
dc.contributor.authorArslan, Abdulmuttalip
dc.contributor.authorGorur, Sadik
dc.contributor.authorRifaioglu, Mehmet Murat
dc.contributor.authorCarlioglu, Ayse
dc.date.accessioned2024-09-18T20:25:24Z
dc.date.available2024-09-18T20:25:24Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractTo investigate renal function in idiopathic hypogonadotropic hypogonadic (IHH) patients by measuring glomerular filtration rate (GFR) using modification of diet in renal disease formula, and determine whether there is any relationship between GFR and testosterone levels. Thirty-three patients with IHH and 37 healthy control subjects participated in this study. The IHH group showed statistically significant higher GFR and proteinuria with respect to the control group (163.1 +/- A 46.9 to 117.9 +/- A 30.5 mL/min, p < 0.001; 0.2 +/- A 0.1 to 0.08 +/- A 0.02 mg/dL, p = 0.041, respectively). Uric acid and creatinine levels were statistically lower than in the control group (4.6 +/- A 0.5-3.6 +/- A 0.9 mg/dL, p = 0.02; 0.7 +/- A 0.2 to 0.9 +/- A 0.2 mg/dL, p < 0.001, respectively). Hyperfiltration positively correlated with IHH in multivariate linear regression analyses (beta = 0.591, p < 0.001). In addition, in the IHH group, we found that the GFR increased independently of body mass index and age. Our study confirms that low testosterone in IHH patients is associated with glomerular hyperfiltration. Patients with IHH should be carefully monitored with respect to their GFR.en_US
dc.identifier.doi10.1007/s11255-015-0995-z
dc.identifier.endpage1103en_US
dc.identifier.issn0301-1623
dc.identifier.issn1573-2584
dc.identifier.issue7en_US
dc.identifier.pmid25947333en_US
dc.identifier.scopus2-s2.0-84933181253en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1099en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-015-0995-z
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10289
dc.identifier.volume47en_US
dc.identifier.wosWOS:000356902100009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology and Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlomerular hyperfiltrationen_US
dc.subjectHypogonadotropic hypogonadismen_US
dc.subjectTestosteroneen_US
dc.subjectRenal dysfunctionen_US
dc.titleGlomerular hyperfiltration in hypogonadotropic hypogonadic patients: Overlooking a cache?en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
418.61 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu