The co-occurrence of Chiari type 1 malformation with syringomyelia and total situs inversus
[ N/A ]
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Int Scientific Literature, Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Total situs inversus (TSI) is a rare congenital anomaly that often occurs concomitantly with other disorders. TSI is the complete left-to-right inversion of the thoracic and abdominal organs. It develops due to an abnormal rotation of the cardiac tube during embryogenesis, the mechanism of which is of unknown mechanism. Syringomyelia (SM) is an uncommon disease of the spinal cord and is known as the occurrence of a cystic space in the middle of the spinal cord. SM occurs due to spinal cord injury, a primary tumor of the spinal cord, or an extramedullary lesion at the foramen magnum such as a Chiari type I malformation (CMI). In the literature there has been reported association of CMI and SM (CMI/SM) with known genetic syndromes. Case Report: We report a 33-year-old female with CMI/SM coexisting with TSI. Our patient presented with pain in the neck, arm, and upper back. She had no trsuma history. There was dysesthesia in the cervical-2 dermatomes. Radiological tools revealed that CMI/SM with TSI accompanied by no other abnormality. Conclusions: It can be suggested that the existence of this case indicates that genetic factors rnay influence the pathogenesis of some CMI/SM cases.
Açıklama
Anahtar Kelimeler
syringomyelia, total situs inversus, Chiari type 1 malformation
Kaynak
Medical Science Monitor
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
13
Sayı
9
