Methemoglobinemia due to prilocaine administration

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dc.contributor.authorArslan, Mehmet Tayip
dc.contributor.authorArica, Vefik
dc.contributor.authorTutanc, Murat
dc.contributor.authorArica, Secil Gunher
dc.date.accessioned2024-09-18T20:32:49Z
dc.date.available2024-09-18T20:32:49Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPrilocaine is the one of the most utilized agents during dorsal penile block in order to prevent pain during circumcision. It is known that prilocaine may lead to methemoglobinemia in neonates and infants. Here we present a 56 days old male patient with prilocaine induced methemoglobinemia who had been referred to intensive care unit for his frank and instant cyanosis after circumcision. Detailed history taking revealed that he needed 1 mg/kg prilocaine administration twice for adequate anesthesia. Patient had frank cyanosis at administration with no other sign. During admission rate of methemoglobin was 16,2% in the blood of the patient and conservative measures lead to complete resolution of all symptoms. Since infants below six months of age are particularly prone to methemoglobinemia due to their low cytochrome b5 levels and fetal hemoglobine is closer to ferric state than adult hemoglobine, it is emphasized in this paper that other alternative anesthetic agents should be utilized instead of prilocaine for regional anesthesia in infants under six months age. (Turk Arch Ped 2012; 47: 305-6)en_US
dc.identifier.doi10.4274/tpa.308
dc.identifier.endpage306en_US
dc.identifier.issn1306-0015
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84871568237en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://doi.org/10.4274/tpa.308
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11146
dc.identifier.volume47en_US
dc.identifier.wosWOS:000313235200016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurk Pediatri Arsivi-Turkish Archives of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMethemoglobinemiaen_US
dc.subjectprilocainen_US
dc.subjectcircumcisionen_US
dc.titleMethemoglobinemia due to prilocaine administrationen_US
dc.typeArticleen_US

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