Chia seed (Salvia hispanica L.) supplementation may contribute to raising the levels of vitamin B12: An option for the vegan diet

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dc.authoridBilgic, Yasemin/0000-0002-4909-7777
dc.authoridDemir, Enver/0000-0002-2620-6192
dc.contributor.authorDemir, Enver Ahmet
dc.contributor.authorBilgic, Yasemin
dc.date.accessioned2024-09-18T19:54:15Z
dc.date.available2024-09-18T19:54:15Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective The chia seed, an ancient pseudocereal, is rich in omega-3 fatty acids and polyphenols, and has been suggested to possess several health benefits. Although it has gained popularity among nutritionists, little is known about the systemic effects of chia and their interactions. Hence, hepatorenal indicators and plasma vitamin concentrations in chia-supplemented aluminum-exposed rats were investigated. Methods Wistar albino rats were either fed on a chia-rich- or standard-diet for 21 days and exposed to aluminum. Liver function tests (Alanine Aminotransferase, Aspartate Aminotransferase, Alkaline Phosphatase, Lactate Dehydrogenase), kidney function tests (Urea Nitrogen, Creatinine), and vitamin B-12 and folic acid measurements were performed by using an automated analyzer. Results Aluminum exposure had no influence on renal function, as did chia supplementation. However, liver function was disturbed with the exposure to Aluminum and chia was of no use against it. Surprisingly, it was found that the animals fed on a chia-rich diet displayed higher concentrations of vitamin B-12 which was not the case for folic acid. Conclusion It was deduced that a chia-rich diet has no effect on the renal function and is not able to reverse aluminum-induced hepatotoxicity; however, it may be of benefit against vitamin B-12 insufficiency and thus, it may offer a novel treatment option which is particularly important in the vegan diet.en_US
dc.identifier.doi10.1590/1678-9865201932e180249
dc.identifier.issn1415-5273
dc.identifier.issn1678-9865
dc.identifier.scopus2-s2.0-85084199849en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1590/1678-9865201932e180249
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7593
dc.identifier.volume32en_US
dc.identifier.wosWOS:000473797800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPontificia Universidade Catolica Campinasen_US
dc.relation.ispartofRevista De Nutricao-Brazilian Journal of Nutritionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAluminumen_US
dc.subjectChiaen_US
dc.subjectFolic aciden_US
dc.subjectHepatorenal functionen_US
dc.subjectVitamin B12en_US
dc.titleChia seed (Salvia hispanica L.) supplementation may contribute to raising the levels of vitamin B12: An option for the vegan dieten_US
dc.typeArticleen_US

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