Zinc deficiency in patients with recurrent aphthous stomatitis: a pilot study

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dc.contributor.authorOzler, G. S.
dc.date.accessioned2024-09-18T20:02:33Z
dc.date.available2024-09-18T20:02:33Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: Recurrent aphthous stomatitis is a common disease of the oral mucosa, affecting 20 per cent of the general population.(1) However, the aetiology of this disease is unknown. This is the first controlled study to compare zinc levels in recurrent aphthous stomatitis patients with those of a well-matched, healthy, control population. Methods: Twenty-five patients with a history of recurrent aphthous stomatitis and 25 healthy people (control group) took part in the study. Patients aged between 20 and 40 years with recurrent oral aphthous ulcers less than 1 cm in diameter were included. Exclusion criteria were pregnancy and lactation, systemic disease (ulcerative colitis, Crohn's disease, Behcet's disease), any current medication (topical or systemic), dental surgery during the previous month and deficiencies in iron, folic acid or vitamin B1, B2, B6 or B12. Serum zinc levels were compared between patient and control groups. Results: Zinc deficiency was detected in 28 per cent of recurrent aphthous stomatitis patients and in 4 per cent of controls. The mean serum zinc level in the patient group was significantly lower than in the control group. Conclusion: These results suggest an association between zinc deficiency and recurrent aphthous stomatitis.en_US
dc.identifier.doi10.1017/S0022215114001078
dc.identifier.endpage533en_US
dc.identifier.issn0022-2151
dc.identifier.issn1748-5460
dc.identifier.issue6en_US
dc.identifier.pmid24849699en_US
dc.identifier.scopus2-s2.0-84903273275en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage531en_US
dc.identifier.urihttps://doi.org/10.1017/S0022215114001078
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7855
dc.identifier.volume128en_US
dc.identifier.wosWOS:000337966600010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofJournal of Laryngology and Otologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAphthous Stomatitisen_US
dc.subjectRecurrenten_US
dc.subjectZincen_US
dc.titleZinc deficiency in patients with recurrent aphthous stomatitis: a pilot studyen_US
dc.typeArticleen_US

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