Effect of Ankaferd Blood Stopper on muscle healing

Basit Öğe Kaydı
dc.authoridYAVUZ, OSMAN/0000-0003-4141-2944
dc.contributor.authorUygun, Murat
dc.contributor.authorYavuz, Osman Y.
dc.contributor.authorUras, Ismail
dc.contributor.authorDuman, Ibrahim G.
dc.contributor.authorHaltas, Hacer
dc.contributor.authorKomurcu, Mahmut
dc.date.accessioned2024-09-18T21:06:49Z
dc.date.available2024-09-18T21:06:49Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: Ankaferd Blood Stopper (ABS), which is a standardized mixture of herbal extracts obtained from five plants, has been proven as an efficient hemostatic agent and is still used in emergency situations. It is not known exactly if decreased bleeding has positive or negative effects on muscle healing and fibrosis, so the purpose of this study was to test the effect of ABS on muscle healing and morphology. Methods: A total of 66 outbred Wistar rats were divided into three control and three experimental subgroups. In the experimental groups, ABS was sprayed on the cut surface of the soleus. In the control groups, a saline solution was sprayed on the cut surface of the soleus. Subgroups were euthanized after 2 weeks, 3 weeks and 4 weeks, respectively. In each subgroup, eight rats were used for the biomechanical study to determine muscle healing and three rats were used for the histopathological investigation. Results: Although muscle strength in the control groups was lower than that of the experimental groups in early weeks, no differences were found between the control and the experimental groups at 4 weeks. Conclusions: ABS has no negative effect on muscle healing. We also observed that ABS accelerated muscle healing compared to the control group. ABS could be used in hemostasis of open fractures and elective orthopedic surgeries.en_US
dc.identifier.endpageS191en_US
dc.identifier.issn0147-958X
dc.identifier.issn1488-2353
dc.identifier.issue6en_US
dc.identifier.pmid27917816en_US
dc.identifier.scopus2-s2.0-85010006031en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageS187en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13827
dc.identifier.volume39en_US
dc.identifier.wosWOS:000389725000036en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCanadian Soc Clinical Investigationen_US
dc.relation.ispartofClinical and Investigative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEfficacyen_US
dc.titleEffect of Ankaferd Blood Stopper on muscle healingen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu