Correlation between proteinuria level and renal morphology with special reference to electron microscopy in kidney donors

Basit Öğe Kaydı
dc.authorid, ahmet/0000-0001-6274-5700
dc.authoridOzdemir, B.Handan/0000-0002-7528-3557
dc.authoridUNLUKAL, NEJAT/0000-0002-8107-4882
dc.contributor.authorNacar, Ahmet
dc.contributor.authorKarabay, Guelten
dc.contributor.authorUnlukal, Nejat
dc.contributor.authorYazici, Canan
dc.contributor.authorOzdemir, Handan
dc.date.accessioned2024-09-18T20:28:16Z
dc.date.available2024-09-18T20:28:16Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aims of this study were to evaluate whether there is a correlation between protein level in urine and renal morphology in kidney transplant donors, as well as to detect the role of electron microscopy. For this purpose, kidney biopsies of 10 donors with urine protein levels were evaluated. Seven patients were female and three were male. Two had physiologic proteinuria (< 150 mg/24h), four had non-significant proteinuria (150-300 mg/24h), and three had significant (> 300 mg/24h) proteinuria. Serum creatinine levels were in normal ranges in all patients except for one who had a slight increase (1.76 mg/dL). Seven cases were reported to have normal or nonspecific light microscopic findings. Two of those seven cases had physiologic proteinuria, three had nonsignificant proteinuria, and two had significant proteinuria. One case had IgA nephropathy with significant proteinuria. One donor had early stage focal segmental glomerulosclerosis with non-significant proteinuria, and one donor had focal interstitial fibrosis with normal urine protein level. There was no statistically significant difference between score means of ultrastructural morphology of the six patients with same patients' light microscopic results and score means of light microscopic results with urine protein levels of all patients. However, there was a significant difference between score means of ultrastructural morphology with urine protein levels of those six patients. In conclusion, urine protein levels and light microscopic findings did not always reflect the detailed morphology alone and together. Therefore, combining with electron microscopic examination could be more beneficial in relieving problems occurring in long-term prognoses.en_US
dc.identifier.doi10.1080/08860220802064713
dc.identifier.endpage511en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue5en_US
dc.identifier.pmid18569931en_US
dc.identifier.scopus2-s2.0-45749096646en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage507en_US
dc.identifier.urihttps://doi.org/10.1080/08860220802064713
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10822
dc.identifier.volume30en_US
dc.identifier.wosWOS:000257070000006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectkidney donoren_US
dc.subjectelectron microscopyen_US
dc.subjectcorrelationen_US
dc.subjectlight microscopyen_US
dc.titleCorrelation between proteinuria level and renal morphology with special reference to electron microscopy in kidney donorsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin / Full Text
Boyut:
704.51 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu