Acute chest syndrome in severity of sickle cell diseases

Basit Öğe Kaydı
dc.contributor.authorHelvaci, Mehmet Rami
dc.contributor.authorAcipayam, Can
dc.contributor.authorAydogan, Akin
dc.contributor.authorAkkucuk, Seckin
dc.contributor.authorOruc, Cem
dc.contributor.authorGokce, Cumali
dc.date.accessioned2024-09-18T19:50:19Z
dc.date.available2024-09-18T19:50:19Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Sickle cell diseases (SCDs) are chronic inflammatory processes on capillary level. We tried to understand whether or not there are some positive correlations between acute chest syndrome (ACS) and severity of SCDs. Methods: All patients with the SCDs were taken into the study. Results: The study included 337 cases (167 females). There were 15 patients (4.4%) with the ACS. The mean ages were similar in both groups (29.4 versus 29.7 years in the ACS group and other, respectively, P > 0.05). The female ratios were similar in both groups, too (60.0% versus 49.0%, respectively, P > 0.05). Additionally, prevalences of associated thalassemia minors were similar in them (66.6% versus 65.5%, respectively, P > 0.05). Smoking was higher in the ACS group (20.0% versus 13.9%), but the difference was nonsignificant (P > 0.05). Although the mean white blood cell count and hematocrit value of peripheric blood were higher in the ACS group, the mean platelet count was lower in them, but the differences were nonsignificant again (P > 0.05 for all). On the other hand, although the painful crises per year, tonsilectomy, priapism, ileus, digital clubbing, pulmonary hypertension, rheumatic heart disease, cirrhosis, stroke, and mortality were higher in the ACS group, the difference was only significant for the stroke (P < 0.05), probably due to the small sample size of the ACS group. Conclusion: SCDs are chronic destructive processes on capillaries iniatiating at birth, and terminate with early organ failures in life. Probably ACS is one of the terminal consequences of the inflammatory processes that may indicate shortened survival in such patients.en_US
dc.identifier.endpage5795en_US
dc.identifier.issn1940-5901
dc.identifier.issue12en_US
dc.identifier.pmid25664108en_US
dc.identifier.startpage5790en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7353
dc.identifier.volume7en_US
dc.identifier.wosWOS:000348303600151en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute chest syndromeen_US
dc.subjectsickle cell diseasesen_US
dc.subjectchronic capillary damageen_US
dc.subjectatherosclerosisen_US
dc.titleAcute chest syndrome in severity of sickle cell diseasesen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
7353.pdf
Boyut:
223.82 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu