A novel enema method can prevent infectious complications of transrectal ultrasound-guided prostate biopsy: A single-centre experience

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dc.authoridKulak, Bilal/0000-0002-8630-0797
dc.authoriducurmak, Ferhat/0000-0002-0513-8944
dc.authoridGokalp, Fatih/0000-0003-3099-3317
dc.authoridKoras, omer/0000-0001-9749-5254
dc.authoridTamkac, Nezih/0000-0001-6903-7010
dc.authoridGORUR, Sadik/0000-0002-3458-5428
dc.contributor.authorGokalp, Fatih
dc.contributor.authorKoras, Omer
dc.contributor.authorGursoy, Didar
dc.contributor.authorSigva, Hakan
dc.contributor.authorPorgali, Sefa Burak
dc.contributor.authorTamkac, Nezih
dc.contributor.authorKulak, Bilal
dc.date.accessioned2024-09-18T21:05:14Z
dc.date.available2024-09-18T21:05:14Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground TRUS biopsy is the preferred method for diagnosing prostate cancer, but it can cause infectious complications that arise with the contribution of fluoroquinolone resistance. We aimed to explore the potential protective effect of a second rectal enema before biopsy. Methods From January 2015 to December 2020, 419 patients were assessed retrospectively. Patients with a history of anticoagulant use, uncontrolled diabetes, urological surgery, prostate biopsy or recent hospitalisation or overseas travel, as well as those with the previous prostatitis, were excluded from the study. The patients were subsequently divided into two groups: Group 1 (n = 223) had received one enema, on the morning of the biopsy and Group 2 (n = 196) had received two, with the additional enema administered half an hour before the procedure. Results There was no significant difference between the groups in terms of age(P = .076), BMI (P = .489), diabetes (P = .265), prostate-specific antigen (PSA) level (P = .193), free/total PSA (f/t PSA) ratio (P = .518) and prostate size (P = .661) or in relation to cancer detection (P = .428). The median hospitalisation date was significantly higher in Group 1 (P = .003) as was urinary tract infection (UTI) development (P = .004). However, there was no significant difference in terms of fever and sepsis (P = .524 and P = .548, respectively). Additionally, subgroup analysis demonstrated that UTI was significantly lower in patients with diabetes mellitus who had received a second enema (P = .004), though there was no significant difference in UTI between the groups in those without diabetes mellitus (P = .215). Multivariable analysis showed that age and diabetes were significant risk factors for the development of UTI (OR: 1.074, 95% CI: 1.027-1.130, P = .002 and OR: 1.220, 95% CI: 0.131-0.665, P = .003, respectively). Furthermore, the second enema was a significant protective factor for preventing UTI (OR: -1.794, 95% CI: 2.208-16.389, P < .001). Conclusion Older age and the presence of diabetes mellitus are independent risk factors for UTI after prostate biopsy. A second enema procedure before biopsy may protect patients from related infectious complications and could therefore be used as an alternative preventative method.en_US
dc.identifier.doi10.1111/ijcp.14923
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue12en_US
dc.identifier.pmid34580970en_US
dc.identifier.scopus2-s2.0-85116292457en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14923
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13466
dc.identifier.volume75en_US
dc.identifier.wosWOS:000703526000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRectal Swab Culturesen_US
dc.subjectPovidone-Iodineen_US
dc.subjectReduced Incidenceen_US
dc.subjectRisken_US
dc.subjectMenen_US
dc.subjectStrategiesen_US
dc.subjectBacteremiaen_US
dc.subjectCanceren_US
dc.titleA novel enema method can prevent infectious complications of transrectal ultrasound-guided prostate biopsy: A single-centre experienceen_US
dc.typeArticleen_US

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